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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.


  • Lark or owl? PER3 is the answer | Cross-references to CCDS and GeneReviews | UniParc cross-references with protein and gene names | FTP ...
    UniProt release 2014_07

  • Everything you always wanted to know about sperm-egg interaction | Extension of the UniProtKB accession number format | SAAS data remova...
    UniProt release 2014_06

  • A flounder... on the rocks! | Update of ECO mapping for evidences | Cross-references for isoform sequences: RefSeq | Addition of cross-r...
    UniProt release 2014_05

  • An old unwanted guest being shown the door | Cross-references for isoform sequences: Ensembl Genomes
    UniProt release 2014_04

News archive

Getting started

  • Text search
    Our basic text search allows you to search all the resources available

    Find regions of similarity between your sequences

  • Sequence alignments
    Align two or more protein sequences using the Clustal Omega program

  • Upload lists
    This tool merges the "Retrieve" and "ID Mapping" tools

UniProt data

Protein spotlight

it did it its way

Temperatures can get cold. And living organisms have to find ways of keeping themselves warm. Humans use clothes. Polar bears grow fur. Whales are lined with blubber. And many animals avoid the cold by migrating to warmer parts of the planet. But for cold-blooded animals - such as fish - things are sometimes more complicated. Especially when they live in waters which are ice-cold, on a seasonal basis or not…