The molecular heterogeneity of protein kinase C and its implications for cellular regulation.
Protein kinase C is now known to be a large family of proteins, with multiple subspecies that have subtle individual enzymological characteristics. Some members of the family exhibit distinct patterns of tissue expression and intracellular localization; different kinases probably have distinct functions in the processing and modulation of a variety of physiological and pathological responses to external signals.
Nature 334:661-665(1988) [ PubMed | SRS | CiteXplore ]
