Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase.
Braun T., Bober E., Singh S., Agarwal D.P., Goedde H.W.
A full-length cDNA clone coding for human mitochondrial aldehyde dehydrogenase (ALDH I) was isolated from a human fetal muscle cDNA library. Sequence analysis revealed structural similarities between the amino-terminal end of ALDH I and other known targeting sequences responsible for protein uptake into the mitochondria.
