glycosid.txt
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UniProt - Swiss-Prot Protein Knowledgebase
Swiss Institute of Bioinformatics (SIB); Geneva, Switzerland
European Bioinformatics Institute (EBI); Hinxton, United Kingdom
Protein Information Resource (PIR); Washington DC, USA
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Description: Glycosyl hydrolase families: classification and list of
entries
Name: glycosid.txt
Release: 55.5 of 10-Jun-2008
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This document provides both a brief description of the classification of
glycosyl hydrolases into families as developed by Bernard Henrissat as well
as the list, classified by family, of the glycosyl hydrolases entries in
Swiss-Prot.
Comments about the glycosyl hydrolases families classification should be
sent to:
Bernard Henrissat
AFMB-CNRS
31 Chemin Joseph Aiguier
13402 Marseille cedex 20
France
E-mail: bernie@afmb.cnrs-mrs.fr
CAZy, a WWW resource on glycosyl hydrolases is available at:
http://www.cazy.org/
============================
Glycosyl hydrolases families
============================
Introduction
------------
O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes which
hydrolyse the glycosidic bond between two or more carbohydrates or between
a carbohydrate and a non-carbohydrate moiety. The IUB-MB Enzyme nomenclature
of glycosyl hydrolases is based on their substrate specificity and
occasionally on their molecular mechanism; such a classification does not
reflect (and was not intended to) the structural features of these enzymes.
A classification of glycosyl hydrolases in families based on amino acid
sequence similarities has been proposed a few years ago. Because there is a
direct relationship between sequence and folding similarities, such a
classification is expected to: (i) reflect the structural features of these
enzymes better than their sole substrate specificity, (ii) help to reveal
the evolutionary relationships between these enzymes and (iii) provide a
convenient tool to derive mechanistic information [1-2]. This document
provides an updated list of the glycosyl hydrolase families. Because the
fold of proteins is better conserved than their sequences, some of the
families can be grouped in 'clans' (i) when new sequences are found to be
related to more than one family, (ii) when the sensitivity of sequence
comparison methods is increased or (iii) when structural determinations
demonstrate the resemblance between members of different families [3]. The
established 'clans' are also listed in this document.
Catalytic mechanism
-------------------
Enzymatic hydrolysis of the glycosidic bond takes place via general acid
catalysis that requires two critical residues: a proton donor and a
nucleophile/base [4]. This hydrolysis occurs via two major mechanisms giving
rise to either an overall retention, or an inversion, of anomeric
configuration. For each families listed in this document we indicate, when
it is known, the stereochemical outcome of the reaction catalyzed as well as
the type of amino-acid residues acting as a nucleophile/base and as a proton
donor.
Clans
-----
Name Families belonging to the clan
---- --------------------------------
GH-A 1,2,5,10,17,26,30,35,39,42,51,53
GH-B 7,16
GH-C 11,12
GH-D 27,36
GH-E 33,34
GH-F 43,62
GH-G 37,63
GH-H 13,70
Note
----
Some glycosyl hydrolases are multifunctional enzymes that contain catalytic
domains that belong to different GH families. The Swiss-Prot entries for
these proteins are therefore mentionned in each of the relevant list of
family members.
References
----------
[ 1] Henrissat B.
A classification of glycosyl hydrolases based on amino-acid sequence
similarities.
Biochem. J. 280:309-316(1991).
[ 2] Henrissat B., Bairoch A.
New families in the classification of glycosyl hydrolases based on amino-
acid sequence similarities.
Biochem. J. 293:781-788(1993).
[ 3] Henrissat B., Bairoch A.
Updating the sequence-based classification of glycosyl hydrolases.
Biochem. J. 316:695-696(1996).
[ 4] Davies G., Henrissat B.
Structures and mechanisms of glycosyl hydrolases.
Structure 3:853-859(1995).
---------------------------------------------------------------
==========================================
Swiss-Prot entries for glycosyl hydrolases
==========================================
========
Family 1
========
Description: Mainly beta-glucosidases (EC 3.2.1.21); 6-phospho-beta-
galactosidases (EC 3.2.1.85); 6-phospho-beta-glucosidases
(EC 3.2.1.86); lactase-phlorizin hydrolases (EC 3.2.1.108);
and myrosinases (EC 3.2.3.1).
PROSITE: PDOC00495
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental) but absent in myrosinases
Clan: GH-A.
Known taxonomic range: eukaryota, bacteria, archaea.
ABGA_CLOLO (Q46130), ARBB_ERWCH (P26206), ASCB_ECOLI (P24240),
BGAL_PYRWO (O52629), BGAL_SULAC (P14288), BGAL_SULSH (P50388),
BGAL_SULSO (P22498), BGL1_ARATH (Q9SE50), BGL1_BACSU (P40740),
BGL2_BACSU (P42403), BGLA_BACCI (Q03506), BGLA_BACSU (P42973),
BGLA_CLOTH (P26208), BGLA_ECOLI (Q46829), BGLA_ENTAG (Q59437),
BGLA_PAEPO (P22073), BGLA_THEMA (Q08638), BGLA_THENE (O33843),
BGLB_ECOLI (P11988), BGLB_MICBI (P38645), BGLB_PAEPO (P22505),
BGLC_MAIZE (P49235), BGLS_AGRSA (P12614), BGLS_CALSA (P10482),
BGLS_TRIRP (P26204), BGLT_TRIRP (P26205), CASB_KLEOX (Q48409),
GBA3_CAVPO (P97265), GBA3_HUMAN (Q9H227), GBA3_PONAB (Q5RF65),
KLOTB_HUMAN (Q86Z14), KLOTB_MOUSE (Q99N32), KLOT_HUMAN (Q9UEF7),
KLOT_MACFA (Q8WP17), KLOT_MOUSE (O35082), KLOT_RAT (Q9Z2Y9),
LACG1_STRPN (Q97SA9), LACG1_STRR6 (Q8DQZ1), LACG2_STRPN (Q97QL9),
LACG2_STRR6 (Q8DPP6), LACG_CLOAB (Q97EZ2), LACG_LACAC (P50977),
LACG_LACCA (P14696), LACG_LACLA (P11546), LACG_LACRH (Q29ZJ1),
LACG_STAA1 (A7X569), LACG_STAA2 (A6U3R9), LACG_STAA3 (Q2FEU3),
LACG_STAA8 (Q2G2D5), LACG_STAA9 (A5IUX8), LACG_STAAB (Q2YYJ9),
LACG_STAAC (Q5HE16), LACG_STAAE (A6QJ33), LACG_STAAM (P67767),
LACG_STAAN (P67768), LACG_STAAR (Q6GEP0), LACG_STAAS (Q6G7C5),
LACG_STAAT (A8YYF6), LACG_STAAU (P11175), LACG_STAAW (P67769),
LACG_STAEQ (Q5HM41), LACG_STAES (Q8CNF8), LACG_STAHJ (Q4L868),
LACG_STRA3 (Q8E4S2), LACG_STRGC (Q9EV38), LACG_STRMU (P50978),
LACG_STRP1 (Q99Y18), LACG_STRP3 (Q8K5V1), LACG_STRP6 (Q5X9Y7),
LACG_STRP8 (Q8NZE1), LACG_STRPB (Q1J9V2), LACG_STRPC (Q1JK01),
LACG_STRPD (Q1JEZ3), LACG_STRPF (Q1J4Q7), LACG_STRPG (A2RGE8),
LACG_STRPM (Q48RC8), LACG_STRSV (A3CPH0), LCTL_HUMAN (Q6UWM7),
LCTL_MOUSE (Q8K1F9), LPH_HUMAN (P09848), LPH_RABIT (P09849),
LPH_RAT (Q02401), MYR1_SINAL (P29737), MYR2_SINAL (P29738),
MYR3_SINAL (P29092), MYRA_SINAL (P29736), MYRO_ARATH (P37702),
MYRO_BRANA (Q00326), MYRO_BREBR (P83179)
========
Family 2
========
Description: Mainly beta-galactosidases (EC 3.2.1.23), beta-glucuronidases
(EC 3.2.1.31) and beta-mannosidases (EC 3.2.1.25).
PROSITE: PDOC00531
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-A.
Known taxonomic range: eukaryota, bacteria.
BGA2_ECOLI (P06864), BGAL_ACTPL (P70753), BGAL_AGRRD (P30812),
BGAL_ARTSB (Q59140), BGAL_BACHD (Q9K9C6), BGAL_BACME (O52847),
BGAL_CLOAB (P24131), BGAL_ECOLI (P00722), BGAL_ENTCL (Q47077),
BGAL_KLEPN (P06219), BGAL_KLULA (P00723), BGAL_LACAC (O07684),
BGAL_LACDA (Q1G9Z4), BGAL_LACDE (P0C1Y0), BGAL_LACHE (Q7WTB4),
BGAL_LACLA (Q48727), BGAL_LACSK (Q48846), BGAL_LEULA (Q02603),
BGAL_PSEHA (P81650), BGAL_RHIME (Q59750), BGAL_STAXY (O33815),
BGAL_STRTR (P23989), BGAL_THEMA (Q56307), BGAL_THEP3 (P77989),
BGAL_THETU (P26257), BGLR_CANFA (O18835), BGLR_CERAE (O77695),
BGLR_ECOLI (P05804), BGLR_FELCA (O97524), BGLR_HUMAN (P08236),
BGLR_MOUSE (P12265), BGLR_PIG (Q4FAT7), BGLR_PONAB (Q5R5N6),
BGLR_RAT (P06760), EBM_ARATH (Q75W54), EBM_LILLO (Q5H7P5),
GUSL1_HUMAN (Q9NQQ0), GUSL3_HUMAN (Q15487), GUSL4_HUMAN (Q15488),
GUSL5_HUMAN (A6NI90), GUSL6_HUMAN (A8K1Q0), GUSP1_HUMAN (Q15486),
MANBA_ASPNG (Q9UUZ3), MANBA_BOVIN (Q29444), MANBA_CAEEL (Q93324),
MANBA_CAPHI (Q95327), MANBA_HUMAN (O00462), MANBA_MOUSE (Q8K2I4),
MANBA_RAT (Q4FZV0)
========
Family 3
========
Description: Mainly beta-glucosidases (EC 3.2.1.21).
PROSITE: PDOC00621
3D structure status: Not available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: ?
Catalytic proton donor: ?
Clan: None
Known taxonomic range: eukaryota, bacteria.
Note: an Asp is proposed as a catalytic residue, but it is not known if it is
the nucleophile or the proton donor.
BGL1_ASPAC (P48825), BGL1_SACFI (P22506), BGL2_SACFI (P22507),
BGL3_ASPWE (P29090), BGLB_CLOTH (P14002), BGLS_AGRTU (P27034),
BGLS_BUTFI (P16084), BGLS_HANAN (P06835), BGLS_KLUMA (P07337),
BGLS_RUMAL (P15885), BGLS_SCHCO (P29091), BGLX_ECOLI (P33363),
BGLX_ERWCH (Q46684), BGLX_SALTY (Q56078), HEXA_PSEO7 (P48823),
NAG3_CELFI (Q7WUL3), NAGZ_ACTP2 (A3N1B7), NAGZ_ACTSZ (A6VKU4),
NAGZ_ALHEH (Q0A911), NAGZ_AZOSE (Q5P081), NAGZ_BORA1 (Q2KXM7),
NAGZ_BORBR (Q7WH65), NAGZ_BORPA (Q7W9J5), NAGZ_BORPE (Q7VWV8),
NAGZ_CHRVO (Q7NWB7), NAGZ_ECO24 (A7ZKL1), NAGZ_ECO57 (P58067),
NAGZ_ECOHS (A7ZZ65), NAGZ_ECOK1 (A1AA01), NAGZ_ECOL6 (Q8FIN2),
NAGZ_ECOLC (B1IUF8), NAGZ_ECOLI (P75949), NAGZ_ECOUT (Q1RD47),
NAGZ_ENTS8 (A7MFT1), NAGZ_ERWCT (Q6D674), NAGZ_HAEDU (Q7VNI8),
NAGZ_HAEI8 (Q4QLU8), NAGZ_HAEIE (A5UDA9), NAGZ_HAEIN (P44955),
NAGZ_HAES1 (Q0I414), NAGZ_HAES2 (B0UTC6), NAGZ_IDILO (Q5QUZ5),
NAGZ_MANSM (Q65VK7), NAGZ_METCA (Q606N2), NAGZ_METFK (Q1H075),
NAGZ_NEIG1 (Q5FA94), NAGZ_NEIM0 (A9M1Z4), NAGZ_NEIMA (Q9JVT3),
NAGZ_NEIMB (Q9K0Q4), NAGZ_NEIMF (A1KSD9), NAGZ_NITEC (Q0AF74),
NAGZ_NITEU (Q82SJ8), NAGZ_NITMU (Q2Y863), NAGZ_NITOC (Q3J953),
NAGZ_PASMU (Q9CPH0), NAGZ_PHOLL (Q7N397), NAGZ_PHOPR (Q6LJ30),
NAGZ_PSEAB (Q02PG9), NAGZ_PSEAE (Q9HZK0), NAGZ_PSYIN (A1SW90),
NAGZ_SALCH (Q57QE6), NAGZ_SALPA (Q5PGT0), NAGZ_SALPB (A9N5J6),
NAGZ_SALTI (Q8Z7I6), NAGZ_SALTY (Q8ZQ06), NAGZ_SHEFN (Q080R9),
NAGZ_SHEON (Q8EEW2), NAGZ_SHESA (A0KXK3), NAGZ_SHESM (Q0HJG7),
NAGZ_SHESR (Q0HVQ8), NAGZ_SHIBS (Q31ZG4), NAGZ_SHIDS (Q32EW7),
NAGZ_SHIFL (Q7UCW4), NAGZ_SHISS (Q3Z310), NAGZ_THICR (Q31G32),
NAGZ_THIDA (Q3SKU2), NAGZ_VIBC3 (A5F8Y1), NAGZ_VIBCH (Q9KU37),
NAGZ_VIBFU (P96157), NAGZ_XANAC (Q8PMU1), NAGZ_XANC5 (Q3BVU6),
NAGZ_XANC8 (Q4USG7), NAGZ_XANCP (Q8PB42), NAGZ_XANOM (Q2P4L0),
NAGZ_XANOR (Q5H1Q0), NAGZ_XYLFA (Q9PAZ0), NAGZ_XYLFT (Q87BR5),
NAGZ_YERE8 (A1JME4), NAGZ_YERP3 (A7FH41), NAGZ_YERPE (Q8ZFS3),
NAGZ_YERPS (Q669N5), XYNB_PRUPE (P83344), YBBD_BACSU (P40406)
========
Family 4
========
Description: Bacterial alpha-galactosidases (EC 3.2.1.22), 6-phospho-beta-
glucosidases (EC 3.2.1.86) and 6-phospho-alpha-D-glucosidases
(EC 3.2.1.122).
PROSITE: PDOC01027
3D structure status: Not available
Reaction stereochemical outcome: Not known
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: None
Known taxonomic range: bacteria.
AGAL_BACSU (O34645), AGAL_ECOLI (P06720), AGAL_RHIME (Q9X4Y0),
AGAL_SALTY (P30877), AGLA_THEMA (O33830), AGLB_KLEPN (Q9AGA6),
BGLT_THEMA (Q9X108), CHBF_ECOLI (P17411), GLVA_BACSU (P54716),
GLVG_ECOLI (P31450), LICH_BACSU (P46320), LPLD_BACSU (P39130),
MALH_CLOAB (Q97LM4), MALH_FUSMR (O06901), PAGL_CLOAB (Q97DP6)
========
Family 5
========
Description: Mainly endoglucanases (EC 3.2.1.4). Contains also beta-mannanases
(EC 3.2.1.78) and exo-1,3-glycanases (EC 3.2.1.58).
PROSITE: PDOC00565
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-A
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family A.
EXG1_HANAN (O93939), EXG1_SCHPO (Q9URU6), EXG1_YEAST (P23776),
EXG2_HANAN (O93983), EXG2_SCHPO (Q10444), EXG2_YEAST (P52911),
EXG3_SCHPO (O74799), EXG_ASPOR (Q7Z9L3), EXG_BLUGR (Q96V64),
EXG_CANAL (P29717), EXG_CANOL (Q8NKF9), EXG_DEBOC (Q12700),
EXG_KLULA (Q12628), EXG_PICAN (Q12626), EXG_SACBA (Q876J3),
EXG_SACKL (Q875R9), EXG_YARLI (Q12725), GUN1_ACIC1 (P54583),
GUN1_ACRSP (P82288), GUN1_BACS4 (P06566), GUN1_BACSU (P07983),
GUN1_BUTFI (P20847), GUN1_CRYFL (Q04469), GUN1_RALSO (P58599),
GUN1_RUMAL (P16216), GUN2_BACS4 (P06565), GUN2_BACSU (P10475),
GUN2_RALSO (P17974), GUN2_TRIRE (P07982), GUN3_BACS4 (P19570),
GUN3_BACSU (P23549), GUN3_FIBSU (P14250), GUN3_HUMIN (Q12624),
GUN4_RUMAL (Q07940), GUN5_BACAG (O85465), GUN5_THEFU (Q01786),
GUNA_BUTFI (P22541), GUNA_CLOCE (P17901), GUNA_CLOLO (P54937),
GUNA_GLOTR (P84194), GUNA_RUMAL (P23660), GUNA_RUMFL (P16169),
GUNA_STRLI (P27035), GUNA_XANCP (P19487), GUNB_CLOCL (P28621),
GUNB_CLOTH (P04956), GUNB_NEOPA (Q12647), GUNB_PAELA (P23550),
GUNB_RUMAL (P23661), GUNC_CLOSF (P23340), GUNC_CLOTH (A3DJ77),
GUNC_CLOTM (P0C2S3), GUNC_PSEFL (P27033), GUND_CELFI (P50400),
GUND_CLOCE (P25472), GUND_CLOCL (P28623), GUNE_CLOTM (P10477),
GUNG_CLOTH (Q05332), GUNN_ERWCT (Q59394), GUNV_PECCC (Q47096),
GUNW_PECCC (Q59395), GUNZ_DICD3 (P07103), GUN_BACS1 (P06564),
GUN_BACS6 (P19424), GUN_CLOSA (P15704), GUN_PAEPO (P23548),
GUN_ROBSP (P23044), GUN_SCHCO (P81190), MAN1_ARATH (Q9FZ29),
MAN1_ORYSJ (Q0JKM9), MAN1_SOLLC (O48540), MAN2_ARATH (Q7Y223),
MAN2_ORYSJ (Q0JJD4), MAN2_SOLLC (Q9FZ03), MAN3_ARATH (Q9SG94),
MAN3_ORYSJ (Q0DM48), MAN3_SOLLC (Q9FUQ6), MAN4_ARATH (Q9SG95),
MAN4_ORYSJ (Q10B67), MAN4_SOLLC (Q8L5J1), MAN5_ARATH (Q9M0H6),
MAN5_ORYSJ (Q5W6G0), MAN5_SOLLC (Q6YM50), MAN6_ARATH (Q9LZV3),
MAN6_ORYSJ (Q0DCM5), MAN7_ARATH (Q9FJZ3), MAN7_ORYSJ (Q2RBB1),
MAN8_ORYSJ (Q0IQJ7), MAN9_ORYSJ (Q6Z310), MANA_MYTED (Q8WPJ2),
MANA_STRLI (P51529), MANP_ARATH (Q9LW44), SPR1_SACBA (Q876J2),
SPR1_YEAST (P32603), YBQ6_YEAST (P38081), YIS7_YEAST (P40566)
========
Family 6
========
Description: Endoglucanases (EC 3.2.1.4) and cellobiohydrolases (EC 3.2.1.91).
PROSITE: PDOC00563
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: Asp (experimental)
Catalytic proton donor: Asp (experimental)
Clan: None
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family B.
GUN1_STRHA (P33682), GUN1_STRSS (P13933), GUN2_THEFU (P26222),
GUN6_HUMIN (Q7SIG5), GUNA_CELFI (P07984), GUNA_MICBI (P26414),
GUNB_FUSOX (P46236), GUX2_TRIRE (P07987), GUX3_AGABI (P49075),
GUX6_HUMIN (Q9C1S9), GUXA_CELFI (P50401)
========
Family 7
========
Description: Endoglucanases (EC 3.2.1.4) and cellobiohydrolases (EC 3.2.1.91).
PROSITE: None
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-B
Known taxonomic range: eukaryota.
Note: formerly known as cellulase family C.
GUN1_HUMGT (Q12622), GUN1_HUMIN (P56680), GUN1_TRILO (Q12714),
GUN1_TRIRE (P07981), GUNC_FUSOX (P46237), GUX1A_NEUCR (Q7SA23),
GUX1B_NEUCR (P38676), GUX1_ASPAC (O59843), GUX1_COCCA (Q00328),
GUX1_CRYPA (Q00548), GUX1_HUMGT (P15828), GUX1_PENJA (Q06886),
GUX1_PHACH (P13860), GUX1_TRIHA (Q9P8P3), GUX1_TRIKO (P62695),
GUX1_TRIRE (P62694), GUX1_TRIVI (P19355), GUX2_AGABI (Q92400),
GUXC_FUSOX (P46238)
========
Family 8
========
Description: Mostly endoglucanases (EC 3.2.1.4).
PROSITE: PDOC00640
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: Asp (inferred)
Catalytic proton donor: Glu (experimental)
Clan: None
Known taxonomic range: bacteria.
Note: formerly known as cellulase family D.
GUB_BACCI (P19254), GUN2_CLOJO (P37701), GUNA_ACEXY (P37696),
GUNA_CLOTH (A3DC29), GUNA_CLOTM (P0C2S2), GUNC_CLOCE (P37699),
GUNY_DICD3 (P27032), GUN_BACSZ (P29019), GUN_CELUD (P18336),
GUN_ECO57 (Q8X5L9), GUN_ECOLI (P37651), GUN_PSEFL (Q8RSY9),
GUN_SALTI (Q8Z289), GUN_SALTY (Q8ZLB7), GUN_XANAC (P58935)
========
Family 9
========
Description: Mostly endoglucanases (EC 3.2.1.4).
PROSITE: PDOC00511
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: Asp (experimental)
Catalytic proton donor: Glu (experimental)
Clan: None
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family E.
CELK_CLOTH (A3DCH1), CELK_CLOTM (P0C2S1), GUN10_ARATH (Q8LCP6),
GUN10_ORYSJ (Q84R49), GUN11_ARATH (O48766), GUN11_ORYSJ (Q7XTH4),
GUN12_ARATH (O64889), GUN12_ORYSJ (Q7XUK4), GUN13_ARATH (O64890),
GUN13_ORYSI (A2XYW8), GUN13_ORYSJ (Q0J930), GUN14_ARATH (Q8S8Q4),
GUN14_ORYSJ (P0C1U5), GUN15_ARATH (O80497), GUN15_ORYSJ (Q6L4I2),
GUN16_ARATH (Q8VYG3), GUN16_ORYSJ (Q654U4), GUN17_ARATH (O81416),
GUN17_ORYSJ (Q652F9), GUN18_ARATH (Q9SZ90), GUN18_ORYSJ (Q5Z9P8),
GUN19_ARATH (Q8L7I0), GUN19_ORYSJ (Q6YXT7), GUN1_ARATH (Q9SRX3),
GUN1_ORYSJ (Q5NAT8), GUN1_PERAE (P05522), GUN1_STRRE (Q05156),
GUN20_ARATH (Q9SUS0), GUN20_ORYSJ (Q6ZA06), GUN21_ARATH (Q9STW8),
GUN21_ORYSJ (Q84Q51), GUN22_ARATH (Q9SVJ4), GUN22_ORYSJ (Q6H3Z9),
GUN23_ARATH (Q8GY58), GUN23_ORYSJ (Q69NF5), GUN24_ARATH (Q93YQ7),
GUN24_ORYSJ (Q69SG5), GUN25_ARATH (Q38890), GUN2_ARATH (Q9FXI9),
GUN2_ORYSJ (Q5NAT0), GUN2_PERAE (P23666), GUN3_ARATH (Q2V4L8),
GUN3_ORYSJ (Q8LQ92), GUN4_ARATH (O49296), GUN4_BACS5 (P28622),
GUN4_ORYSJ (Q6Z715), GUN4_THEFU (P26221), GUN5_ARATH (Q9M995),
GUN5_ORYSJ (Q67UW5), GUN6_ARATH (Q42059), GUN6_DICDI (P22699),
GUN6_ORYSJ (Q6Z2J3), GUN7_ARATH (O04478), GUN7_ORYSJ (Q6Z5P2),
GUN8_ARATH (Q9CAC1), GUN8_ORYSJ (Q6K7G9), GUN9_ARATH (Q9C9H5),
GUN9_ORYSJ (P0C1U4), GUNA_BACPU (Q5YLG1), GUNA_FIBSU (P23665),
GUNA_PSEFL (P10476), GUNB_CELFI (P26225), GUNC_BUTFI (P23658),
GUNC_CELFI (P14090), GUND_CLOTH (A3DDN1), GUND_CLOTM (P0C2S4),
GUNF_CLOTH (P26224), GUNG_CLOCE (P37700), GUNI_CLOTH (Q02934),
GUNX_PRUPE (P38534), GUNZ_CLOSR (P23659), GUN_PHAVU (P22503)
=========
Family 10
=========
Description: Mostly xylanases (EC 3.2.1.8).
PROSITE: PDOC00510
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-A
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family F.
CEXY_CLOSR (P40942), GUNF_FUSOX (P46239), GUX_CELFI (P07986),
XLNA_AGABI (O60206), XYN1_BACST (P40943), XYN2_BACST (P45703),
XYN4_CALSA (P23557), XYNA_ASPAC (O59859), XYNA_ASPKA (P33559),
XYNA_BACHD (P07528), XYNA_BACOV (P49942), XYNA_BUTFI (P23551),
XYNA_CALSA (P23556), XYNA_CALSR (P40944), XYNA_CRYAL (P07529),
XYNA_DICB4 (P80718), XYNA_DICTH (Q12603), XYNA_GLOTR (P84195),
XYNA_PENCH (P29417), XYNA_PENSI (P56588), XYNA_PRERU (P48789),
XYNA_PSEFL (P14768), XYNA_STRLI (P26514), XYNA_THEAU (P23360),
XYNA_THEMA (Q60037), XYNA_THENE (Q60042), XYNA_THESA (P36917),
XYNB_BUTFI (P26223), XYNB_DICB4 (P80717), XYNB_PSEFL (P23030),
XYNB_THENE (Q60041), XYNC_EMENI (Q00177), XYNX_CLOTM (P38535),
XYNY_CLOTM (P51584), XYNZ_CLOTH (P10478)
=========
Family 11
=========
Description: Mostly xylanases (EC 3.2.1.8).
PROSITE: PDOC00622
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-C
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family G.
XY11A_PSEXY (P83513), XYN1_ASPAW (P55328), XYN1_ASPNG (P55329),
XYN1_ASPTU (P55331), XYN1_COCCA (Q06562), XYN1_HUMIN (P55334),
XYN1_TRIRE (P36218), XYN2_ASPNG (P55330), XYN2_MAGGR (P55335),
XYN2_TRIRE (P36217), XYN3_ASPKA (P33557), XYNA1_CLOSR (Q8GJ44),
XYNA2_CLOSR (P33558), XYNA_BACCI (P09850), XYNA_BACPU (P00694),
XYNA_BACST (P45705), XYNA_BACSU (P18429), XYNA_CLOSA (P17137),
XYNA_EMENI (P55332), XYNA_NEOPA (P29127), XYNA_PAEVA (P81536),
XYNA_PIRSP (Q12667), XYNA_SCHCO (P35809), XYNA_THELA (O43097),
XYNB_ASPKA (P48824), XYNB_EMENI (P55333), XYNB_STRLI (P26515),
XYNC_FIBSU (P35811), XYNC_STRCO (Q9RI72), XYNC_STRLI (P26220),
XYND_CELFI (P54865), XYN_PHACE (O97402), XYN_TRIHA (P48793)
=========
Family 12
=========
Description: Endoglucanases (EC 3.2.1.4).
PROSITE: None
3D structure status: Not available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (inferred)
Catalytic proton donor: Glu (inferred)
Clan: GH-C
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family H.
GUNA_ASPKA (Q12679), GUNB_GLOTR (P84196), GUNS_PECCC (P16630),
GUN_ASPAC (P22669)
=========
Family 13
=========
Description: Mostly alpha-amylases (EC 3.2.1.1); pullulanases (EC 3.2.1.41);
cyclomaltodextrin glucanotransferase (EC 2.4.1.19);
cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate
hydrolase (EC 3.2.1.93); malto-oligosyltrehalose
trehalohydrolase (EC 3.2.1.141).
PROSITE: None
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Asp (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-H
Known taxonomic range: eukaryota, bacteria.
AAM1_RHOSH (Q9JN46), AGLA_RHIME (Q9Z3R8), AGL_PEDPE (P43473),
AM4N_DROAN (Q23834), AMT4_PSESA (P22963), AMT4_PSEST (P13507),
AMT6_BACS7 (P19571), AMY1_AEDAE (P53354), AMY1_AERHY (P22630),
AMY1_DEBOC (P19269), AMY1_DROAN (Q23835), AMY1_ECOLI (P25718),
AMY1_HORVU (P00693), AMY1_HUMAN (P04745), AMY1_LIPKO (Q01117),
AMY1_MOUSE (P00687), AMY1_ORYSJ (P17654), AMY1_SACFI (P21567),
AMY1_SCHPO (O14154), AMY2A_ORYSI (A2YGY2), AMY2A_ORYSJ (Q0D9J1),
AMY2B_HUMAN (P19961), AMY2_DEBOC (Q08806), AMY2_DICTH (P14898),
AMY2_DROAN (O18345), AMY2_ECOLI (P26612), AMY2_HORVU (P04063),
AMY2_SALTY (P26613), AMY2_SCHPO (Q09840), AMY3A_ORYSJ (P27932),
AMY3B_ORYSJ (P27937), AMY3C_ORYSJ (P27939), AMY3D_ORYSJ (P27933),
AMY3E_ORYSJ (P27934), AMY3_DICTH (P14899), AMY3_HORVU (P04747),
AMY3_SCHPO (Q9Y7S9), AMY3_WHEAT (P08117), AMY4_HORVU (P04748),
AMY4_SCHPO (O42918), AMY5_HORVU (P04749), AMY6_HORVU (P04750),
AMYA1_ASPOR (P0C1B3), AMYA3_ASPOR (P0C1B4), AMYA_AERHY (P41131),
AMYA_ASPAW (Q02905), AMYA_ASPNG (P56271), AMYA_DROMA (P54215),
AMYA_DROME (P08144), AMYA_DROYA (P83833), AMYA_VIGMU (P17859),
AMYB_ASPAW (Q02906), AMYB_DROME (P81641), AMYB_DROYA (Q9BN01),
AMYC1_ORYSI (A2WPU3), AMYC1_ORYSJ (Q0JMV4), AMYM_BACAD (P32818),
AMYM_BACLI (Q04977), AMYM_BACST (P19531), AMYP_HUMAN (P04746),
AMYP_MOUSE (P00688), AMYP_PIG (P00690), AMYP_RAT (P00689),
AMYP_STRCA (P83053), AMYR_DROAN (O18344), AMYR_DROAP (O77011),
AMYR_DROAV (O77020), AMYR_DROBA (O77019), AMYR_DROBC (O76284),
AMYR_DROBP (Q9NJN8), AMYR_DRODO (O77021), AMYR_DROEC (O77012),
AMYR_DROEL (Q9NJP0), AMYR_DROER (O76265), AMYR_DROJA (Q9GQV3),
AMYR_DROKI (O77013), AMYR_DROLN (O76262), AMYR_DROMA (O77014),
AMYR_DROME (O18408), AMYR_DROOR (O77015), AMYR_DROPN (O77022),
AMYR_DROPS (O18552), AMYR_DROSE (O76261), AMYR_DROSI (O77016),
AMYR_DROSR (O76459), AMYR_DROSU (O18420), AMYR_DROTE (O76260),
AMYR_DROTK (O77018), AMYR_DROVA (Q9NJN7), AMYR_DROWI (O76263),
AMYR_DROYA (O76264), AMYS_NEIME (Q84HD6), AMYS_NEIPO (Q9ZEU2),
AMY_ASPSH (P30292), AMY_BACAM (P00692), AMY_BACCI (P08137),
AMY_BACLI (P06278), AMY_BACME (P20845), AMY_BACST (P06279),
AMY_BACSU (P00691), AMY_BUTFI (P30269), AMY_CLOAB (P23671),
AMY_DERPT (P49274), AMY_PECMA (P91778), AMY_PHACE (O97396),
AMY_PSEHA (P29957), AMY_STRGR (P30270), AMY_STRHY (P08486),
AMY_STRLI (Q05884), AMY_STRLM (P09794), AMY_STRTL (P27350),
AMY_STRVL (P22998), AMY_TENMO (P56634), AMY_THECU (P29750),
AMY_TRICA (P09107), APU_THEP3 (P38939), APU_THESA (P36905),
APU_THETU (P38536), APU_THETY (P16950), CDAS_BACSH (Q08341),
CDAS_THEP3 (P29964), CDGT1_BACCI (P30920), CDGT1_PAEMA (P04830),
CDGT2_BACCI (P43379), CDGT2_PAEMA (P31835), CDGT_BAC11 (P30921),
CDGT_BACLI (P14014), CDGT_BACOH (P27036), CDGT_BACS0 (P05618),
CDGT_BACS2 (P31746), CDGT_BACS3 (P09121), CDGT_BACS8 (P17692),
CDGT_BACSS (P31747), CDGT_BACST (P31797), CDGT_BREBE (O30565),
CDGT_KLEOX (P08704), CDGT_THETU (P26827), DEXB_STREQ (Q59905),
DEXB_STRMU (Q99040), DEXB_STRPN (Q54796), GLGB1_CLOPE (Q8XPA2),
GLGB1_CLOPS (Q0SWZ1), GLGB1_RHIEC (Q2K487), GLGB1_RHIL3 (Q1MBS9),
GLGB1_STRAW (Q82JF0), GLGB1_STRCO (Q59833), GLGB1_XANAC (Q8PR13),
GLGB1_XANC5 (Q3BZE1), GLGB1_XANC8 (Q4V0E2), GLGB1_XANCP (Q8PE48),
GLGB1_XANOM (Q2P9F7), GLGB1_XANOR (Q5H6H2), GLGB2_CLOPE (Q8XK15),
GLGB2_CLOPS (Q0SSN2), GLGB2_RHIEC (Q2JZ21), GLGB2_RHIL3 (Q1M3A7),
GLGB2_STRAW (Q825Q8), GLGB2_STRCO (Q59832), GLGB2_XANAC (Q8PQA2),
GLGB2_XANC5 (Q3BYI0), GLGB2_XANC8 (Q4UZL7), GLGB2_XANCP (Q8PDD1),
GLGB2_XANOM (Q2P949), GLGB2_XANOR (Q5H6Q3), GLGB_ACTSZ (A6VP15),
GLGB_AGRT5 (Q8U8L4), GLGB_AGRTU (P52979), GLGB_ALHEH (Q0AA26),
GLGB_ANASP (Q8YYX9), GLGB_ANAVT (Q3M473), GLGB_AQUAE (O66936),
GLGB_ASHGO (Q757Q6), GLGB_ASPOR (Q96VA4), GLGB_AZOSE (Q5NXV7),
GLGB_BACAN (Q81K82), GLGB_BACC1 (Q72YJ3), GLGB_BACCL (P30537),
GLGB_BACCN (A7GUA1), GLGB_BACCR (Q816G6), GLGB_BACCZ (Q632H1),
GLGB_BACHK (Q6HC15), GLGB_BACLD (Q65FS4), GLGB_BACST (P30538),
GLGB_BACSU (P39118), GLGB_BIFLO (Q8G5L0), GLGB_BORBR (Q7WII7),
GLGB_BORPA (Q7W6L4), GLGB_BORPE (Q7VYK0), GLGB_BRAJA (Q89FD3),
GLGB_BRASB (A5EPZ7), GLGB_BRASO (A4Z005), GLGB_BURCA (Q1BVW7),
GLGB_BURCH (A0KDG4), GLGB_BURCM (Q0B3Y4), GLGB_BURP0 (A3NU16),
GLGB_BURP1 (Q3JTG5), GLGB_BURP6 (A3N8B3), GLGB_BURPS (Q63T91),
GLGB_BURS3 (Q39N89), GLGB_BURTA (Q2T6R3), GLGB_BURVG (A4JR39),
GLGB_BURXL (Q13S07), GLGB_BUTFI (P30539), GLGB_CANGA (Q6FJV0),
GLGB_CHLAB (Q5L6K4), GLGB_CHLCV (Q823Y5), GLGB_CHLFF (Q253M6),
GLGB_CHLMU (Q9PL51), GLGB_CHLPN (Q9Z876), GLGB_CHLTA (Q3KKH0),
GLGB_CHLTR (O84874), GLGB_CITK8 (A8AQY3), GLGB_CLOP1 (Q0TQ16),
GLGB_CORDI (Q6NHR6), GLGB_COREF (Q8FQ12), GLGB_CORGL (Q8NR40),
GLGB_CORJK (Q4JUK5), GLGB_CRYNE (Q5KP87), GLGB_DEBHA (Q6BXN1),
GLGB_DECAR (Q47II8), GLGB_DEIGD (Q1IZQ3), GLGB_DEIRA (Q9RTB7),
GLGB_DESDG (Q30Z14), GLGB_DESHY (Q24VW3), GLGB_DESVH (Q729V5),
GLGB_DESVV (A1VC54), GLGB_DICDI (Q555Q9), GLGB_ECO24 (A7ZSW5),
GLGB_ECO57 (Q8X6X6), GLGB_ECOHS (A8A5P2), GLGB_ECOK1 (A1AGW5),
GLGB_ECOL5 (Q0TC27), GLGB_ECOL6 (Q8FCR7), GLGB_ECOLC (B1IP32),
GLGB_ECOLI (P07762), GLGB_ECOUT (Q1R5J4), GLGB_EMENI (Q9Y8H3),
GLGB_ENT38 (A4WFL5), GLGB_ERWCH (Q8GQC5), GLGB_ERWCT (Q6CZK0),
GLGB_FELCA (Q6T308), GLGB_FRAP2 (B0TZI5), GLGB_FRASC (Q2J6Q9),
GLGB_FRAT1 (Q14J36), GLGB_FRATF (A7NAI2), GLGB_FRATH (Q2A4U7),
GLGB_FRATN (A0Q593), GLGB_FRATO (Q0BN67), GLGB_FRATT (Q5NHN4),
GLGB_FRATW (A4IZK2), GLGB_FUSNN (Q8RF62), GLGB_GLOIN (Q8NKE1),
GLGB_GLOVI (Q7NL20), GLGB_GRABC (Q0BU54), GLGB_HAEI8 (Q4QK67),
GLGB_HAEIG (A5UEJ2), GLGB_HAEIN (P45177), GLGB_HAES1 (Q0I3H7),
GLGB_HAES2 (B0UU89), GLGB_HORSE (Q6EAS5), GLGB_HUMAN (Q04446),
GLGB_JANSC (Q28MN2), GLGB_KLEP7 (A6TF51), GLGB_KLULA (Q6CX53),
GLGB_LACAC (Q5FL68), GLGB_LACPL (Q890J1), GLGB_LACS1 (Q1WSM8),
GLGB_LEIXX (Q6AEU4), GLGB_MAGMM (Q2W2Q6), GLGB_MAIZE (Q08047),
GLGB_MANSM (Q65TI0), GLGB_MESSB (Q11EX1), GLGB_METCA (Q608L5),
GLGB_METFK (Q1H1K2), GLGB_MOUSE (Q9D6Y9), GLGB_MYCBO (P59816),
GLGB_MYCBP (A1KIB6), GLGB_MYCPA (Q73X75), GLGB_MYCSJ (A3Q396),
GLGB_MYCSK (A1UJW9), GLGB_MYCSS (Q1B568), GLGB_MYCTA (A5U226),
GLGB_MYCTU (Q10625), GLGB_MYCUA (A0PUI6), GLGB_MYXXD (Q1D654),
GLGB_NEIDE (Q9RQI5), GLGB_NITEC (Q0AGJ0), GLGB_NITEU (Q81ZU6),
GLGB_NITHX (Q1QNB1), GLGB_NITMU (Q2YB47), GLGB_NITOC (Q3JCN0),
GLGB_NITWN (Q3STC2), GLGB_NOCFA (Q5Z0W8), GLGB_NOVAD (Q2G7S5),
GLGB_OCEIH (Q8CZE8), GLGB_ORYSJ (Q01401), GLGB_PARUW (Q6MAB4),
GLGB_PASMU (Q9CN94), GLGB_PHOPR (Q6LHN1), GLGB_PICTO (Q6L2Z9),
GLGB_PROAC (Q6A8Q7), GLGB_PROM0 (A3PBV8), GLGB_PROM1 (A2C142),
GLGB_PROM2 (A8G3V0), GLGB_PROM3 (A2CAR9), GLGB_PROM5 (A2BVP7),
GLGB_PROM9 (Q31BV0), GLGB_PROMA (Q7VBL4), GLGB_PROMM (Q7V8B5),
GLGB_PROMP (Q7V299), GLGB_PROMS (A2BQ65), GLGB_PROMT (Q46LW6),
GLGB_PSE14 (Q48IE2), GLGB_PSEA6 (Q15VD0), GLGB_PSEA7 (A6V628),
GLGB_PSEAE (Q9I1W2), GLGB_PSEF5 (Q4KCQ3), GLGB_PSEPF (Q3KD78),
GLGB_PSEPK (Q88FN1), GLGB_PSESM (Q881X0), GLGB_PSEU2 (Q4ZTJ2),
GLGB_RALEH (Q0K0X8), GLGB_RALEJ (Q46TF2), GLGB_RALSO (Q8XT76),
GLGB_RHILO (Q985P4), GLGB_RHIME (Q92M14), GLGB_RHOBA (Q7UVH1),
GLGB_RHOFD (Q21WG7), GLGB_RHOMR (Q93HU3), GLGB_RHOP2 (Q2IYX0),
GLGB_RHOP5 (Q07K87), GLGB_RHOPA (Q6N3P9), GLGB_RHOPB (Q210H1),
GLGB_RHOPS (Q133N2), GLGB_RHORT (Q2RR72), GLGB_RHOS1 (A3PIQ5),
GLGB_RHOS4 (Q3J3M6), GLGB_RHOSR (Q0SGR9), GLGB_ROSDO (Q165E2),
GLGB_RUBXD (Q1AZ86), GLGB_SACD2 (Q21M30), GLGB_SALAR (A9MMA0),
GLGB_SALCH (Q57IT8), GLGB_SALPA (Q5PM06), GLGB_SALPB (A9MTV4),
GLGB_SALRD (Q2S4A0), GLGB_SALTI (Q8Z235), GLGB_SALTY (Q8ZLG5),
GLGB_SERP5 (A8GKV0), GLGB_SHEB5 (A3D286), GLGB_SHEB8 (A6WKY2),
GLGB_SHEB9 (A9KTJ1), GLGB_SHEFN (Q081Q4), GLGB_SHEON (Q8EGU7),
GLGB_SHEPC (A4Y4U3), GLGB_SHESM (Q0HGI8), GLGB_SHESR (Q0HST5),
GLGB_SHESW (A1RLX8), GLGB_SHIBS (Q31VJ1), GLGB_SHIDS (Q32AV3),
GLGB_SHIF8 (Q0SZN2), GLGB_SHIFL (Q83PV3), GLGB_SHISS (Q3YW93),
GLGB_SOLTU (P30924), GLGB_STRA1 (Q3K1K5), GLGB_STRA3 (Q8E5V8),
GLGB_STRA5 (Q8E081), GLGB_STRAU (P52980), GLGB_STRGC (A8AYH3),
GLGB_STRMU (Q8DT52), GLGB_STRP2 (Q04KG8), GLGB_STRPN (Q97QS8),
GLGB_STRR6 (Q8DPS6), GLGB_STRSV (A3CM01), GLGB_SYNEL (Q8DLB8),
GLGB_SYNJA (Q2JT08), GLGB_SYNJB (Q2JK68), GLGB_SYNP6 (Q5N4W5),
GLGB_SYNP7 (P16954), GLGB_SYNPW (A5GJR7), GLGB_SYNPX (Q7U646),
GLGB_SYNR3 (A5GSG4), GLGB_SYNS3 (Q0I8Y2), GLGB_SYNS9 (Q3AYE2),
GLGB_SYNSC (Q3AKV6), GLGB_SYNY3 (P52981), GLGB_THEFY (Q47SE7),
GLGB_THICR (Q31IB6), GLGB_THIDA (Q3SH78), GLGB_TRIEI (Q114I1),
GLGB_VIBCH (Q9KNE8), GLGB_VIBF1 (Q5DZB8), GLGB_VIBPA (Q87FR0),
GLGB_VIBVU (Q8D4P0), GLGB_VIBVY (Q7MG90), GLGB_YARLI (Q6CCT1),
GLGB_YEAST (P32775), GLGB_YERE8 (A1JSJ0), GLGB_YERP3 (A7FNX5),
GLGB_YERPA (Q1C1D9), GLGB_YERPE (Q8ZA75), GLGB_YERPN (Q1CDL3),
GLGB_YERPP (A4TQV2), GLGB_YERPS (Q664I2), GLGE_MYCBO (P63532),
GLGE_MYCS2 (Q9RP48), GLGE_MYCTU (P63531), GLGX_CITK8 (A8AQY2),
GLGX_ECO24 (A7ZSW4), GLGX_ECO57 (Q8X6X8), GLGX_ECOHS (A8A5P1),
GLGX_ECOK1 (A1AGW4), GLGX_ECOL5 (Q0TC28), GLGX_ECOL6 (Q8FCR8),
GLGX_ECOLC (B1IP33), GLGX_ECOLI (P15067), GLGX_ECOUT (Q1R5J5),
GLGX_ERWCH (Q8KR69), GLGX_HAEIN (P45178), GLGX_MYCBO (P0A4Y5),
GLGX_MYCTU (P0A4Y4), GLGX_SALCH (Q57IT9), GLGX_SALPA (Q5PM07),
GLGX_SALPB (A9MTV3), GLGX_SALTI (Q8Z234), GLGX_SALTY (Q8ZLG6),
GLGX_SHIBS (Q31VJ2), GLGX_SHIDS (Q32AV4), GLGX_SHIF8 (Q0SZN3),
GLGX_SHIFL (Q83J89), GLGX_SHISS (Q3YW94), GLGX_YERE8 (A1JSI8),
GLGX_YERP3 (A7FNX4), GLGX_YERPA (Q1C1E0), GLGX_YERPE (Q8ZA76),
GLGX_YERPN (Q1CDL4), GLGX_YERPP (A4TQV1), GLGX_YERPS (Q664I3),
ISOA_FLASP (O32611), ISOA_PSEAY (P10342), ISOA_PSEUM (P26501),
MAL12_YEAST (P53341), MAL1_APIME (Q17058), MAL1_DROME (P07191),
MAL1_DROVI (O16098), MAL2_DROME (P07190), MAL2_DROVI (O16099),
MAL32_YEAST (P38158), MAL3_DROME (P07192), MAL62_YEAST (P07265),
MALT_AEDAE (P13080), MALT_BACTQ (P80072), MALT_CANAL (Q02751),
MALT_SCHPO (Q9P6J3), MALX1_YEAST (P40884), MALX2_YEAST (P40439),
MALX3_YEAST (P53051), MALX4_YEAST (Q08295), MALZ_ECOLI (P21517),
MGTA_THEMA (P80099), MGTA_THENE (O86956), NEPU1_THEVU (Q60053),
NEPU2_THEVU (Q08751), NEPU_BACST (P38940), O16G_BACCE (P21332),
O16G_BACCO (Q45101), O16G_BACF5 (P29093), O16G_BACHD (Q9K8U9),
O16G_BACSU (O06994), O16G_BACTR (P29094), PEP1A_STRCO (Q9L1K2),
PEP1B_STRCO (Q9KY04), PULA_KLEAE (P07811), PULA_KLEPN (P07206),
PULA_THEMA (O33840), TREC_BACSU (P39795), TREC_ECOLI (P28904),
TRES_PIMSR (P72235), TRES_THETH (O06458), TREY_ARTSQ (Q44315),
TREY_MYCTU (Q10768), TREZ_ARTRM (Q9AJN6), TREZ_ARTSQ (Q44316),
TREZ_BREHE (O52520), TREZ_MYCTU (Q10769), TREZ_RHIS1 (Q53238),
YEI1_SCHPO (O13996), YQ29_SCHPO (Q10427)
=========
Family 14
=========
Description: Beta-amylases (EC 3.2.1.2)
PROSITE: PDOC00414
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: ?
Catalytic proton donor: ?
Known taxonomic range: eukaryota, bacteria.
Note: a Glu is proposed as a catalytic residue, but it is not known if it is
the nucleophile or the proton donor.
AMYB_ARATH (P25853), AMYB_BACCE (P36924), AMYB_BACCI (P06547),
AMYB_BACFI (P96513), AMYB_HORSP (P82993), AMYB_HORVU (P16098),
AMYB_IPOBA (P10537), AMYB_MAIZE (P55005), AMYB_MEDSA (O22585),
AMYB_SECCE (P30271), AMYB_SOYBN (P10538), AMYB_THETU (P19584),
AMYB_TRIRP (O65015), AMYB_VIGUN (O64407), AMYB_WHEAT (P93594)
=========
Family 15
=========
Description: Glucoamylases (EC 3.2.1.3).
PROSITE: PDOC00646
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: Glu
Catalytic proton donor: Glu
Clan: None
Known taxonomic range: eukaryota, bacteria, archaea.
AMYG_ARXAD (P42042), AMYG_ASPAW (P69327), AMYG_ASPKA (P23176),
AMYG_ASPNG (P69328), AMYG_ASPOR (P36914), AMYG_ASPSH (P22832),
AMYG_CLOS0 (P29761), AMYG_HORRE (Q03045), AMYG_NEUCR (P14804),
AMYG_RHIOR (P07683), AMYG_SACFI (P08017), AMYG_SCHPO (O60087),
AMYG_YEAST (P08019), AMYH_SACFI (P26989), AMYH_YEAST (P04065),
AMYI_YEAST (P29760), Y1610_METJA (Q59005)
=========
Family 16
=========
Description: Mainly bacterial beta-glucanases (EC 3.2.1.73) (lichenases).
PROSITE: PDOC00794
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-B
Known taxonomic range: bacteria.
AGAR_STRCO (P07883), BRU1_SOYBN (P35694), CGKA_ALTCA (P43478),
CRF1_ASPFU (Q8J0P4), CRF2_ASPFU (Q4WI46), CRH1_YEAST (P53301),
CRH2_YEAST (P32623), CRR1_ASHGO (Q75A41), CRR1_YEAST (Q05790),
E13B_BACCI (P23903), EGLC_RHIME (Q9Z3Q2), EXOK_RHIME (P33693),
EXSH_RHIME (O33680), GUB_BACAM (P07980), GUB_BACLI (P27051),
GUB_BACSU (P04957), GUB_BREBE (P37073), GUB_CLOTH (A3DBX3),
GUB_CLOTM (Q84C00), GUB_FIBSU (P17989), GUB_ORPSP (O14412),
GUB_PAEMA (P23904), GUB_PAEPO (P45797), GUB_RHOMR (P45798),
XTH10_ARATH (Q9ZVK1), XTH11_ARATH (Q9SMP1), XTH12_ARATH (Q9FKL9),
XTH13_ARATH (Q9FKL8), XTH14_ARATH (Q9ZSU4), XTH15_ARATH (Q38911),
XTH16_ARATH (Q8LG58), XTH17_ARATH (O80803), XTH18_ARATH (Q9M0D2),
XTH19_ARATH (Q9M0D1), XTH1_ARATH (Q9SV61), XTH1_SOLLC (Q40144),
XTH20_ARATH (Q9FI31), XTH21_ARATH (Q9ZV40), XTH22_ARATH (Q38857),
XTH23_ARATH (Q38910), XTH24_ARATH (P24806), XTH25_ARATH (Q38907),
XTH26_ARATH (Q9SVV2), XTH27_ARATH (Q8LDS2), XTH28_ARATH (Q38909),
XTH29_ARATH (Q8L7H3), XTH2_ARATH (Q9SV60), XTH30_ARATH (Q38908),
XTH31_ARATH (P93046), XTH32_ARATH (Q9SJL9), XTH33_ARATH (Q8LC45),
XTH3_ARATH (Q9LJR7), XTH4_ARATH (Q39099), XTH5_ARATH (Q9XIW1),
XTH6_ARATH (Q8LF99), XTH7_ARATH (Q8LER3), XTH8_ARATH (Q8L9A9),
XTH8_ORYSJ (Q76BW5), XTH9_ARATH (Q8LDW9), XTHA_PHAAN (Q41638),
XTHB_PHAAN (Q8LNZ5), XTH_BRAOB (Q6YDN9), XTH_SOYBN (Q39857),
XTH_TOBAC (P93349), XTH_WHEAT (Q41542), YHZ7_SCHPO (Q9USW3)
=========
Family 17
=========
Description: Glucan endo-1,3-beta-glucosidases (EC 3.2.1.39) and lichenases
(EC 3.2.1.73).
PROSITE: PDOC00507
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu
Catalytic proton donor: Glu
Clan: GH-A
Known taxonomic range: eukaryota.
Note: currently has only been found in plants and in fungi.
BGL2_CANAL (P43070), BGL2_SCHPO (O13990), BGL2_YEAST (P15703),
E1310_ARATH (Q9FHX5), E1311_ARATH (Q8L868), E1312_ARATH (Q8VYE5),
E1313_ARATH (Q9FJU9), E1314_ARATH (Q9ZQG9), E131_ARATH (O65399),
E131_SOLTU (P52400), E132_ARATH (Q9C7U5), E132_SOLTU (P52401),
E133_ARATH (Q9ZU91), E133_SOLTU (P52402), E134_ARATH (Q94CD8),
E135_ARATH (Q9M088), E136_ARATH (Q93Z08), E137_ARATH (Q9M069),
E138_ARATH (Q6NKW9), E139_ARATH (Q9FGH4), E13A_ARATH (P33157),
E13A_HORVU (P34742), E13A_SOLLC (Q01412), E13A_SOYBN (Q03773),
E13B_BRACM (P49236), E13B_HEVBR (P52407), E13B_HORVU (P15737),
E13B_MAIZE (P49237), E13B_NICPL (P23431), E13B_PEA (Q03467),
E13B_PHAVU (P23535), E13B_PINHA (P85483), E13B_PRUPE (P52408),
E13B_SOLLC (Q01413), E13B_SOYBN (P52395), E13B_TOBAC (P15797),
E13B_WHEAT (P52409), E13C_HORVU (Q02126), E13C_TOBAC (P23432),
E13D_HORVU (Q02437), E13D_TOBAC (P23433), E13E_HORVU (Q02438),
E13E_TOBAC (P23546), E13F_HORVU (Q02439), E13F_TOBAC (P27666),
E13G_TOBAC (P23547), E13H_TOBAC (P36401), E13I_TOBAC (P52396),
E13J_TOBAC (P52397), E13K_TOBAC (P52398), E13L_TOBAC (P52399),
EA6_ARATH (Q06915), GUB2_HORVU (P12257), GUB_NICPL (P07979),
SCW10_YEAST (Q04951), SCW11_YEAST (P53189), SCW4_YEAST (P53334)
=========
Family 18
=========
Description: Chitinases (EC 3.2.1.14), endo-beta-n-acetylglucosaminidases
(EC 3.2.1.96) and di-N-acetylchitobiases.
PROSITE: PDOC00839
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: carbonyl oxygen of C-2 acetamido group of
substrate
Catalytic proton donor: Glu
Clan: None
Known taxonomic range: eukaryota, bacteria, viridae.
CAI_PHAVU (P84708), CH3L1_BOVIN (P30922), CH3L1_BUBBU (Q7YS85),
CH3L1_CAPHI (Q8SPQ0), CH3L1_HUMAN (P36222), CH3L1_MOUSE (Q61362),
CH3L1_PIG (Q29411), CH3L1_PONAB (Q5RBP6), CH3L1_RAT (Q9WTV1),
CH3L1_SHEEP (Q6TMG6), CH3L2_HUMAN (Q15782), CH3L3_MOUSE (O35744),
CH3L4_MOUSE (Q91Z98), CH47_DROME (Q23997), CHI1_APHAL (P32470),
CHI1_CANAL (P46876), CHI1_COCIM (Q1E3R8), CHI1_COCPO (P54196),
CHI1_RHINI (P29025), CHI1_RHIOL (P29026), CHI1_STROI (P29115),
CHI2_CANAL (P40953), CHI2_COCIM (Q1EAR5), CHI2_COCPO (P54197),
CHI2_RHIOL (P29027), CHI2_STROI (P29116), CHI2_YEAST (Q06350),
CHI3_CANAL (P40954), CHI4_TRIHA (P48827), CHIA1_BACCI (P20533),
CHIA_ARATH (P19172), CHIA_BOVIN (Q95M17), CHIA_CICAR (P36908),
CHIA_CUCSA (P17541), CHIA_ECOLI (P13656), CHIA_HUMAN (Q9BZP6),
CHIA_MOUSE (Q91XA9), CHIA_PHAAN (P29024), CHIA_PSEO7 (P32823),
CHIA_RAT (Q6RY07), CHIA_SERMA (P07254), CHIA_TOBAC (P29060),
CHIB_SERMA (P11797), CHIB_TOBAC (P29061), CHID1_BOVIN (Q5EAB4),
CHID1_DANRE (Q7SYK0), CHID1_DICDI (Q54G42), CHID1_HUMAN (Q9BWS9),
CHID1_MOUSE (Q922Q9), CHID1_PONAB (Q5RFF6), CHID1_RAT (A0JPQ9),
CHID1_XENLA (Q68EX9), CHID1_XENTR (Q66IL0), CHID_BACCI (P27050),
CHID_VIBFU (P96156), CHIE_BETVU (P36910), CHIT1_DROME (Q9W5U3),
CHIT1_HUMAN (Q13231), CHIT1_MOUSE (Q9D7Q1), CHIT1_TULBA (Q9SLP4),
CHIT2_DROME (Q9W092), CHIT2_TULBA (Q7M443), CHIT3_DROME (Q9W5U2),
CHIT3_VITVI (P51614), CHITL_CAEEL (Q18143), CHIT_BRUMA (P29030),
CHIT_CAEEL (Q11174), CHIT_MANSE (P36362), CHIT_NPVAC (P41684),
CHIT_NPVOP (O10363), CHIT_SACEN (P14529), CHIT_STRLI (P36909),
CHIT_STRPL (P11220), CHIT_STRVL (P84754), CHIT_YEAST (P29029),
CHIX_STROI (Q05638), CHLY_HEVBR (P23472), CHLY_PARTH (P23473),
CONB_CANEN (P49347), DIAC1_DICDI (Q7KWW8), DIAC2_DICDI (Q8T293),
DIAC_BOVIN (Q01458), DIAC_HUMAN (Q01459), DIAC_MOUSE (Q8R242),
DIAC_RAT (Q01460), EBA1_FLAME (P36911), EBA2_FLAME (P36912),
EBA3_FLAME (P36913), EBAG_FLAST (P80036), EBAG_STRPL (P04067),
IDGF1_DROME (Q8MM24), IDGF1_DROSI (Q8MX41), IDGF1_DROYA (Q8MX40),
IDGF1_GLOMM (Q2PQN0), IDGF2_DROME (Q9V3D4), IDGF3_DROME (Q8MLZ7),
IDGF3_DROSI (Q8MX32), IDGF3_DROYA (Q8MX31), IDGF4_DROME (Q9W303),
IDGF4_GLOMM (Q2PQM7), IDGF5_DROME (Q8T0R7), IDGF5_GLOMM (Q2PQM6),
IDGFL_BOMMO (Q9GV28), NAHA1_PALCA (P85512), OVGP1_BOVIN (Q28042),
OVGP1_HUMAN (Q12889), OVGP1_MESAU (Q60557), OVGP1_MOUSE (Q62010),
OVGP1_PAPAN (P36718), OVGP1_PIG (Q28990), OVGP1_SHEEP (Q28542),
XIP1_ORYSJ (Q7GCM7), XIP1_WHEAT (Q8L5C6), XIP2_ORYSJ (Q53NL5),
YDHD_BACSU (O05495), YKT4_SCHPO (Q9C105)
=========
Family 19
=========
Description: Chitinases (EC 3.2.1.14).
PROSITE: PDOC00620
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: ?
Catalytic proton donor: ?
Clan: None
Known taxonomic range: eukaryota, bacteria.
CHI1_CASSA (P29137), CHI1_GINBI (P85343), CHI1_GOSHI (Q39799),
CHI1_HORVU (P11955), CHI1_ORYSJ (P24626), CHI1_PEA (P21225),
CHI1_SOLTU (P52403), CHI1_TAXBA (P85337), CHI1_THECC (Q41596),
CHI1_TOBAC (P08252), CHI2_ARAHY (Q06014), CHI2_BRANA (Q09023),
CHI2_GOSHI (Q39785), CHI2_HORVU (P23951), CHI2_ORYSJ (P25765),
CHI2_PEA (P21226), CHI2_SOLTU (P52404), CHI2_TAXBA (P85338),
CHI2_TOBAC (P24091), CHI3_ARAHY (Q06015), CHI3_SOLTU (P52405),
CHI3_TAXBA (P85355), CHI3_TOBAC (P29059), CHI4_ARAHY (Q06016),
CHI4_BRANA (Q06209), CHI4_PHAVU (P27054), CHI4_SOLTU (P52406),
CHI5_PHAVU (P36361), CHI6_POPTR (P16579), CHI8_POPTR (P16061),
CHIA_ARAHY (Q06012), CHIA_MAIZE (P29022), CHIA_SECCE (Q9FRV1),
CHIA_SOLCI (Q40114), CHIA_SOLLC (Q05539), CHIB_ARAHY (Q06013),
CHIB_ARATH (P19171), CHIB_MAIZE (P29023), CHIB_PEA (P21227),
CHIB_POPTR (P29031), CHIB_SOLLC (Q05540), CHIB_VITVI (P51613),
CHIC_POPTR (P29032), CHIC_SECCE (Q9FRV0), CHIC_SOLLC (Q05538),
CHID_SOLLC (Q05537), CHIP_BETVU (P42820), CHIP_TOBAC (P17513),
CHIQ_TOBAC (P17514), CHIT_CARPA (P85084), CHIT_DIOJA (P80052),
CHIT_PETHY (P29021), CHIT_PHAVU (P06215), CHIT_SOLTU (P05315),
CHIX_PEA (P36907), CHLY_CARPA (P81241), IAMY_COILA (P15326)
=========
Family 20
=========
Description: Beta-hexosaminidases (EC 3.2.1.52) and chitobiases (EC 3.2.1.52).
PROSITE: None
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: carbonyl oxygen of C-2 acetamido group of
substrate
Catalytic proton donor: Glu
Clan: None
Known taxonomic range: eukaryota, bacteria.
Note: Two Glu are proposed as catalytic residues.
CHB_SERMA (Q54468), CHB_VIBHA (P13670), FDL_DROME (Q8WSF3),
HEX1_CANAL (P43077), HEX1_VIBFU (P96155), HEX20_CELFI (Q7WUL4),
HEXA1_DICDI (P13723), HEXA2_DICDI (Q54SC9), HEXA_BOVIN (Q0V8R6),
HEXA_CAEBR (Q619W7), HEXA_CAEEL (Q22492), HEXA_ENTHI (P49009),
HEXA_HUMAN (P06865), HEXA_MOUSE (P29416), HEXA_PONAB (Q5RC84),
HEXA_PORGI (P49008), HEXA_RAT (Q641X3), HEXB1_DICDI (Q54K55),
HEXB2_DICDI (Q54K56), HEXB_ENTHI (Q86M34), HEXB_FELCA (P49614),
HEXB_HUMAN (P07686), HEXB_MOUSE (P20060), HEXB_PIG (Q29548),
HEXB_PSEO7 (P49007), HEXB_RAT (Q6AXR4), HEXC_BOMMO (P49010),
HEXDC_BOVIN (A6QNR0), HEXDC_HUMAN (Q8WVB3), HEXDC_MOUSE (Q3U4H6),
HEX_VIBVU (Q04786), STRH_STRPN (P49610)
=========
Family 21
=========
Description: DELETED.
=========
Family 22
=========
Description: Lysozymes type C (EC 3.2.1.17) and alpha-lactalbumins.
PROSITE: PDOC00119
3D structure status: Available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Asp
Catalytic proton donor: Glu
Clan: None
Known taxonomic range: eukaryota.
LALB1_HORSE (P08334), LALB2_HORSE (P08896), LALBA_BOSMU (Q9TSR4),
LALBA_BOVIN (P00711), LALBA_BUBBU (Q9TSN6), LALBA_CAMDR (P00710),
LALBA_CANFA (Q9N2G9), LALBA_CAPHI (P00712), LALBA_CAVPO (P00713),
LALBA_EQUAS (P28546), LALBA_FELCA (P37154), LALBA_HUMAN (P00709),
LALBA_MACEU (Q06655), LALBA_MACGI (P19122), LALBA_MACRG (P07458),
LALBA_MOUSE (P29752), LALBA_ORNAN (P30805), LALBA_PAPCY (P12065),
LALBA_PIG (P18137), LALBA_RABIT (P00716), LALBA_RAT (P00714),
LALBA_SHEEP (P09462), LALBA_TACAC (P81646), LALBA_TRIVU (Q29145),
LYS1_MUSDO (Q7YT16), LYSA_DROME (P83971), LYSB_DROME (Q08694),
LYSC1_ANAPL (P00705), LYSC1_ANOGA (Q17005), LYSC1_BOVIN (Q06285),
LYSC1_CANFA (P81708), LYSC1_CAPHI (P37713), LYSC1_HORSE (P11376),
LYSC1_PIG (P12067), LYSC1_RAT (P00697), LYSC1_SHEEP (P17607),
LYSC1_TACAC (P37156), LYSC2_BOVIN (Q06283), LYSC2_CANFA (P81709),
LYSC2_CAPHI (P37714), LYSC2_HORSE (P81710), LYSC2_ONCMY (P11941),
LYSC2_PIG (P12068), LYSC2_RAT (Q05820), LYSC3_ANAPL (P00706),
LYSC3_BOVIN (Q06284), LYSC3_PIG (P12069), LYSC3_SHEEP (Q9TUN1),
LYSCK_SHEEP (P80190), LYSCM_MOUSE (P08905), LYSCN_BOVIN (P80189),
LYSCP_MOUSE (P17897), LYSCT_BOVIN (Q27996), LYSC_AIXSP (Q7LZQ2),
LYSC_ALLNI (P79687), LYSC_AMYCA (P85345), LYSC_AXIAX (P12066),
LYSC_BOVIN (P04421), LYSC_CALJA (P79158), LYSC_CAMDR (P37712),
LYSC_CATWA (Q7LZQ0), LYSC_CERAE (P61633), LYSC_CERTO (P61630),
LYSC_CHEMY (P84492), LYSC_CHICK (P00698), LYSC_CHRAM (P22910),
LYSC_COLAN (P61631), LYSC_COLGU (P61632), LYSC_COLLI (P00708),
LYSC_COLVI (P00700), LYSC_COTJA (P00701), LYSC_CRAFA (Q7LZQ3),
LYSC_EQUAS (P11375), LYSC_ERYPA (P61634), LYSC_FELCA (P37155),
LYSC_FUGRU (P61944), LYSC_GORGO (P79179), LYSC_HALGR (Q659U5),
LYSC_HUMAN (P61626), LYSC_HYLLA (P79180), LYSC_LEPWE (Q659U0),
LYSC_LOPCA (P00699), LYSC_LOPIM (Q7LZP9), LYSC_LOPLE (P24364),
LYSC_MACMU (P30201), LYSC_MELGA (P00703), LYSC_MIOTA (P79806),
LYSC_NASLA (P79811), LYSC_NUMME (P00704), LYSC_OPIHO (Q91159),
LYSC_ORTVE (P00707), LYSC_PANPA (P61627), LYSC_PANTR (P61628),
LYSC_PAPAN (P61629), LYSC_PAROL (Q9DD65), LYSC_PAVCR (P19849),
LYSC_PHACO (P00702), LYSC_PHAVE (P49663), LYSC_PHOVI (Q659U1),
LYSC_PONPY (P79239), LYSC_PSEPE (P21776), LYSC_PYGNE (P79847),
LYSC_RABIT (P16973), LYSC_SAGOE (P79268), LYSC_SAISC (P79294),
LYSC_SCOMX (Q9PU28), LYSC_SEMEN (P67977), LYSC_SYRRE (P24533),
LYSC_SYRSO (P81711), LYSC_TRAFR (P67980), LYSC_TRAOB (P67979),
LYSC_TRASA (Q7LZI3), LYSC_TRATE (Q7LZT2), LYSC_TRAVT (P67978),
LYSC_TRISI (Q7LZQ1), LYSC_TRIVU (P51782), LYSD_DROME (P83972),
LYSE_DROME (P37159), LYSI_BOVIN (Q6B410), LYSM_BOVIN (Q6B411),
LYSP_DROME (P29615), LYSS_DROME (P37160), LYSX_DROME (P37161),
LYS_ANTMY (Q7SID7), LYS_ASTRU (P37715), LYS_BOMMO (P48816),
LYS_BUFAN (P85045), LYS_ESTAC (P82175), LYS_GALME (P82174),
LYS_HYACE (P05105), LYS_HYPCU (P50717), LYS_TRINI (P50718),
LYZL1_BOVIN (A0JNM6), LYZL1_HUMAN (Q6UWQ5), LYZL1_MOUSE (Q9CPX3),
LYZL2_HUMAN (Q7Z4W2), LYZL4_BOVIN (Q2T9N7), LYZL4_HUMAN (Q96KX0),
LYZL4_MOUSE (Q9D925), LYZL5_BOVIN (Q32PD6), LYZL5_HUMAN (Q96QH8),
LYZL5_MOUSE (A2AE20), LYZL6_BOVIN (Q29RT1), LYZL6_HUMAN (O75951),
LYZL6_MOUSE (Q9DA11), SACA3_HUMAN (Q8IXA5), SACA3_MOUSE (Q9D9X8),
SACA3_VULVU (P83198)
=========
Family 23
=========
Description: Lysozymes type G (EC 3.2.1.17).
PROSITE: None
3D structure status: Available
Reaction stereochemical outcome: Not known
Catalytic nucleophile/base: ?
Catalytic proton donor: Glu
Clan: None
Known taxonomic range: eukaryota.
Note: only found in birds so far.
LYG1_HUMAN (Q8N1E2), LYG1_MOUSE (Q9D7Q0), LYG2_HUMAN (Q86SG7),
LYG2_MOUSE (Q3V1I0), LYG_ANSAN (P00718), LYG_CASCA (Q7LZR3),
LYG_CHICK (P27042), LYG_CYGAT (P00717), LYG_CYPCA (Q8JFR1),
LYG_EPICO (Q90X99), LYG_FUGRU (P61133), LYG_PAROL (Q90VZ3),
LYG_STRCA (P00719)
=========
Family 24
=========
Description: Phage lysozymes (EC 3.2.1.17).
PROSITE: None
3D structure status: Available
Reaction stereochemical outcome: Inverted anomeric configuration
Catalytic nucleophile/base: Asp (experimental)
Catalytic proton donor: Glu (experimental)
Clan: None
Known taxonomic range: bacteria, viridae.
LYSD_ECOLI (P78285), LYSQ_ECOLI (P76159), LYST1_DICDI (Q556F2),
LYST2_DICDI (Q86AA1), LYS_BP933 (P68920), LYS_BPAPS (Q9T1T5),
LYS_BPB03 (Q37896), LYS_BPH19 (Q9ZXB7), LYS_BPHP1 (P51728),
LYS_BPLC2 (P62692), LYS_BPMU (Q9T1X2), LYS_BPN15 (O64362),
LYS_BPP1 (Q37875), LYS_BPP2 (P51771), LYS_BPP21 (P27359),
LYS_BPP22 (P09963), LYS_BPPA2 (P10439), LYS_BPPH2 (P11187),
LYS_BPPHV (P62693), LYS_BPPS1 (O80292), LYS_BPPS3 (O80288),
LYS_BPPZA (P07540), LYS_BPT4 (P00720), LYS_BPVT2 (P68921),
LYS_LAMBD (P03706), VG05_BPT4 (P16009), VLYS_BPPRD (P13559)
=========
Family 25
=========
Description: Lysozymes (EC 3.2.1.17).
PROSITE: PDOC00737
3D structure status: Not available
Reaction stereochemical outcome: Not known
Catalytic nucleophile/base: ?
Catalytic proton donor: ?
Clan: None
Known taxonomic range: eukaryota, bacteria, viridae.
CF50_DICDI (Q556R7), LYS4_ENTHI (Q27650), LYSG2_DICDI (Q86KC1),
LYSG3_DICDI (Q8T2I5), LYSG4_DICDI (Q54BQ8), LYSG5_DICDI (Q54BL8),
LYSM1_STRGL (P25310), LYS_BPCP1 (P15057), LYS_BPCP7 (P19385),
LYS_BPCP9 (P19386), LYS_BPMV1 (P33486), LYS_CHASP (P00721),
LYS_CLOAB (P34020), LYS_CLOPE (P26836), YEGX_ECO57 (Q8X7H0),
YEGX_ECOL6 (Q8FFY2), YEGX_ECOLI (P76421)
=========
Family 26
=========
Description: Mainly mannan endo-1,4-beta-mannosidases (EC 3.2.1.78).
PROSITE: None
3D structure status: Not available
Reaction stereochemical outcome: Retained anomeric configuration
Catalytic nucleophile/base: Glu (experimental)
Catalytic proton donor: Glu (experimental)
Clan: GH-A
Known taxonomic range: eukaryota, bacteria.
Note: formerly known as cellulase family I.
MANA_PIRSP (P55296), MANA_PSEFL (P49424), MANA_RHOMR (P49425),
MANB_BACSM (P16699), MANB_BACSU (P55278), MANB_PIRSP (P55297),
MANC_PIRSP (P55298)
=========
Family 27
=========
Description: Alpha-galactosidases (EC 3.2.1.22), alpha-N-
acetylgalactosaminidases (EC 3.2.1.49) and isomalto-dextranases
(EC 3.2.1.94).
PROSITE: PDOC00443
3D structure status: Not available
Reaction stereochemical outcome: Not known
Catalytic nucleophile/base: ?
Catalytic proton donor: ?
Clan: GH-D
Known taxonomic range: eukaryota, bacteria.
AGAL_ASPNG (P28351), AGAL_COFAR (Q42656), AGAL_CYATE (P14749),
AGAL_DICDI (Q55B10), AGAL_HUMAN (P06280), AGAL_MOUSE (P51569),
AGAL_ORYSJ (Q9FXT4), AGAL_SCHPO (Q9URZ0), IMD_ARTGO (Q44052),
MEL1_YEAST (P04824), MEL2_YEAST (P41945), MEL5_YEAST (P41946),
MEL6_YEAST (P41947), MEL_SACMI (Q11129), MEL_SACPA (Q09187),
MEL_SACPS (Q03647), MEL_TORDE (Q9UVD6), MEL_ZYGCI (Q99172),
MEL_ZYGMR (Q9P4V4), NAGAB_BOSIN (P83127), NAG