Unreviewed, UniProtKB/TrEMBL A0A1C3 (A0A1C3_9INFA)

Names and origin

Protein names

Submitted name:
    Polymerase PB2 EMBL ABJ90266.2

Gene names

Name:

PB2 EMBL ABJ90266.2

Organism

Influenza A virus (A/ostrich/Italy/984/00(H7N1)) EMBL ABJ90266.2

Taxonomic identifier

338859 [NCBI]

Taxonomic lineage

Viruses › ssRNA negative-strand viruses › Orthomyxoviridae › Influenzavirus A

Protein attributes

Sequence length	759 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication By similarity. Spearmint SPM001591
Subcellular location	Virion. Nucleus. MitochondrionBy similarity. Spearmint SPM001591

Ontologies

Keywords
Biological process	mRNA capping Spearmint SPM001591 mRNA processing
Cellular component	Mitochondrion Spearmint SPM001591
Gene Ontology (GO)
Biological process	mRNA capping Inferred from electronic annotation. Source: UniProtKB-KW transcription Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro RNA-directed RNA polymerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0A1C3-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 6F27FB6B6630F454	FASTA	759	85,835
	10 20 30 40 50 60 MERIKELRDL MSQSRTREIL TKTTVDHMAI IKKYTSGRQE KNPALRMKWM MAMKYPITAD 70 80 90 100 110 120 KRIMEMIPER NEQGQTLWSR TNDAGSDRVI VSPLAVTWWN RNGPTTSTVH YPKVYKTYFE 130 140 150 160 170 180 KVERLKHGTF GPVHFRNQVK IRRRVDINPG HADLSAKEAQ DVIMEVVFPN EVGARILTSE 190 200 210 220 230 240 SQLTITKEKK EELQDCKIAP LMVAYMLERE LVRKTRFLPV AGGTSSVYIE VLHLTQGTCW 250 260 270 280 290 300 EQMYTPGGEV RNDDVDQSLI IAARNIVRRA TVSADPLASL LEMCHGTQIG GIRMVDILRQ 310 320 330 340 350 360 NPTEEQAVDI CKAAMGLRIS SSFSFGGFTF KRTSGSSVKR EEEVLTGNLQ TLKIRVHEGY 370 380 390 400 410 420 EEFTMVGRRA TAILRKATRR LIQLIVSGRD EQSIAEAIIV AMVFSQEDCM IKAVRGDLNF 430 440 450 460 470 480 VNRANQRLNP MHQLLRHFQK DAKVLFQNWG IEPIDNVMGM IGILPDMTPS TEMSLRGVRV 490 500 510 520 530 540 SKMGVDEYSS TERVVVSIDR FLRVRDQMGN VLLSPEEVSE TQGTEKLTIT YSSSMMWEIN 550 560 570 580 590 600 GPESVLVNTY QWIIKNWETV KIQWSQDPTM LYNKMEFEPF QSLVPKAARG KYSGFVRTLF 610 620 630 640 650 660 QQMRDVLGTF DTVQIIKLLP FAAAPPEQSR MQFSSLTVNV RGSGMRILVR GNSPVFNYNK 670 680 690 700 710 720 ATKRLTVLGK DAGALTEDPD EGTAGVESAV LRGFLILGKE DKRYGPALSI NELSNLAKGE 730 740 750 KANVLIGQGD VVLVMKRKRD SSILTDSQTA TKRIRMAIN

References

[1]

"Pneumo- and neurotropism of avian origin Italian highly pathogenic avian influenza H7N1 isolates in experimentally infected mice." Rigoni M., Shinya K., Toffan A., Milani A., Bettini F., Kawaoka Y., Cattoli G., Capua I. Virology 364:28-35(2007) [PubMed: 17408714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: A/ostrich/Italy/984/00 EMBL ABJ90266.2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ991333 Viral cRNA. Translation: ABJ90266.2. DQ991340 Viral cRNA. Translation: ABJ90276.1.
3D structure databases
SMR	A0A1C3. Positions 685-759.
ModBase	Search...
Family and domain databases
InterPro	IPR001591. RNA_pol_PB2_orthomyxovir. [Graphical view]
Pfam	PF00604. Flu_PB2. 1 hit. [Graphical view]
ProDom	PD001667. Flu_PB2. 1 hit. [Graphical view] [Entries sharing at least one domain]

Entry information

Entry name

A0A1C3_9INFA

Accession

Primary (citable) accession number: A0A1C3
Secondary accession number(s): A0A1D3

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	January 23, 2007
Last modified:	July 22, 2008
This is version 19 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)