Reviewed, UniProtKB/Swiss-Prot A0A885 (PIP_GORGO)

Names and origin

Protein names

Recommended name:
    Prolactin-inducible protein homolog
Alternative name(s):
    Prolactin-induced protein

Gene names

Name:

PIP

Organism

Gorilla gorilla gorilla (Lowland gorilla)

Taxonomic identifier

9595 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Gorilla

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subunit structure	Monomer. Interacts with AZGP1 By similarity.
Subcellular location	SecretedBy similarity.
Sequence similarities	Belongs to the PIP family.

Ontologies

Keywords
Cellular component	Secreted
Coding sequence diversity	Polymorphism
Domain	Signal
PTM	Glycoprotein Pyrrolidone carboxylic acid
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Signal peptide	1 – 28	28	By similarity
	Chain	29 – 146	118	Prolactin-inducible protein homolog
Amino acid modifications
	Modified residue	29	1	Pyrrolidone carboxylic acid By similarity
	Glycosylation	105	1	N-linked (GlcNAc...) Potential
	Disulfide bond	65 ↔ 91		By similarity
	Disulfide bond	89 ↔ 123		By similarity
Natural variations
	Natural variant	113	1	V → I
	Natural variant	118	1	Q → R

Sequences

	Sequence		Length	Mass (Da)
	A0A885-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 435343331212C04E	FASTA	146	16,503
	10 20 30 40 50 60 MRLLQLLFRA SPATLLLVLC LQLGANKAQD NTRKIIIKNF DIPKSVRPND EVTAVLAVQT 70 80 90 100 110 120 ELKECMVVKT YLISSVPLQG AFNYKYTACL CDDNPKTFYW DFYANRTVQI AAVIDVIQEL 130 140 GICPDDAAVI PIKNNRFYTT EILEVE

References

[1]

"Origin and evolution of gene for prolactin-induced protein." Kitano T., Tian W., Umetsu K., Yuasa I., Yamazaki K., Saitou N., Osawa M. Gene 383:64-70(2006) [PubMed: 16949771] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS ILE-113 AND ARG-118. Strain: Isolate T025, Isolate T026 and Isolate T027.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB251901 Genomic DNA. Translation: BAF35621.1. AB251902 Genomic DNA. Translation: BAF35622.1. AB251903 Genomic DNA. Translation: BAF35623.1.
3D structure databases
ModBase	Search...
Phylogenomic databases
HOVERGEN	A0A885.
Family and domain databases
InterPro	IPR007990. SV_autoAg. [Graphical view]
PANTHER	PTHR15096. SV_autoAg. 1 hit.
Pfam	PF05326. SVA. 1 hit. [Graphical view]
PIRSF	PIRSF002572. PIP-GCDFP-15. 1 hit.
ProDom	PD021604. SV_autoAg. 1 hit. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

PIP_GORGO

Accession

Primary (citable) accession number: A0A885
Secondary accession number(s): A0A887

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	July 22, 2008
This is version 7 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)