Reviewed, UniProtKB/Swiss-Prot A6NEL2 (ANR56_HUMAN)

Names and origin

Protein names

Recommended name:
    Ankyrin repeat domain-containing protein 56

Gene names

Name:

ANKRD56

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	793 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 2 ANK repeats.

Ontologies

Keywords
Domain	ANK repeat Repeat
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 793	793	Ankyrin repeat domain-containing protein 56
Regions
	Repeat	630 – 659	30	ANK 1
	Repeat	669 – 699	31	ANK 2
	Compositional bias	121 – 125	5	Poly-Arg
	Compositional bias	134 – 274	141	Ala-rich
	Compositional bias	300 – 304	5	Poly-Gln

Sequences

	Sequence		Length	Mass (Da)
	A6NEL2-1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 8072B1D09C52F32F	FASTA	793	85,742
	10 20 30 40 50 60 MARELSQEAL LDFLCQAGGR VTNAALLSHF KSFLRDPDAS PSQHQHRREL FKGFVNSVAA 70 80 90 100 110 120 VRQDPDGTKY VVLKRRYRDL LGEEGLQRPR EPPAAAPSAG GAAPCSPRGA RRGEPPQQQP 130 140 150 160 170 180 RRRRREKEPE EEPAGAAARA ADAACNGLPG SDSRRAPGKG GGSKGSPGQR PPVPAAAAAG 190 200 210 220 230 240 AQARASCAAA KTQGRCCWEC LQNNLAVLPG ELGALPHSAT AEEKPARALP AQDDRGASRE 250 260 270 280 290 300 REEGALAEPA PVPAVAHSPP ATVEAATSRA SPPALLPGPA PRGDRPELLT PSSLHYSTLQ 310 320 330 340 350 360 QQQQRTREWV ARHPQVPEAR DQGPIRAWSV LPDNFLQLPL EPGSTEPNSE PPDPCLSSHS 370 380 390 400 410 420 LFPVVPDESW ESWAGNPSLT VFRSIRCQLS LQDLDDFVDQ ESDGSEESSS GPKDSPGASE 430 440 450 460 470 480 EGLQVVLGTP DRGKLRNPAG GLSVSRKEGS PSRSPQGLRN RGDGHISQQV PAGANGLAGH 490 500 510 520 530 540 PLKPLPWPVP KLRRSLRRSS LAGRAKLSSS DEEYLDEGLL KRSRRPPRSR KPSKAGTAPS 550 560 570 580 590 600 PRVDAGLSLK LAEVKAVVAE RGWRHSLWVP SGEGSAALAP HRTSEHKSSL VPLDAREHEW 610 620 630 640 650 660 IVKLASGSWI QVWTLFWEDP QLALHKDFLT GYTALHWIAK HGDLRALQDL VSGAKKAGIV 670 680 690 700 710 720 LDVNVRSSCG YTPLHLAAIH GHQGVIKLLV QRLASRVNVR DSSGKKPWQY LTSNTSGEIW 730 740 750 760 770 780 QLLGAPRGKP IFPVYPLVGS SSPTRKAKSK EISRSVTRKT SFAALLKSQH NKWKLANQYE 790 KFHSPREREE YSD

References

[1]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed: 15815621] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC104687 Genomic DNA. No translation available.
RefSeq	NP_001025041.1.
UniGene	Hs.257292
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	A6NEL2.
Genome annotation databases
Ensembl	ENSG00000186212. Homo sapiens. [Contig view]
GeneID	345079.
KEGG	hsa:345079.
NMPDR	fig|9606.3.peg.24294.
Organism-specific databases
HGNC	HGNC:32958. ANKRD56.
GenAtlas	Search...
GeneCards	Search...
Gene expression databases
CleanEx	HS_ANKRD56.
Family and domain databases
InterPro	IPR002110. ANK. [Graphical view]
Pfam	PF00023. Ank. 2 hits. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 2 hits. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 1 hit. [Graphical view]
ProDom	A6NEL2. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ANR56_HUMAN

Accession

Primary (citable) accession number: A6NEL2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	July 24, 2007
Last modified:	July 22, 2008
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)