Reviewed, UniProtKB/Swiss-Prot A7ZTG3 (SECB_ECO24)

Names and origin

Protein names

Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	EcE24377A_4113

Organism

Escherichia coli O139:H28 (strain E24377A / ETEC) [Complete proteome] [HAMAP]

Taxonomic identifier

331111 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein existence

Inferred from homology.

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity.
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 155	155	Protein-export protein secB

Sequences

	Sequence		Length	Mass (Da)
	A7ZTG3-1 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: 00514C5F393A643D	FASTA	155	17,277
	10 20 30 40 50 60 MSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ LADDVYEVVL 70 80 90 100 110 120 RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA YCPNILFPYA RECITSMVSR 130 140 150 GTFPQLNLAP VNFDALFMNY LQQQAGEGTE EHQDA

References

[1]	Rasko D.A., Rosovitz M.J., Brinkley C., Myers G.S.A., Seshadri R., Cer R.Z., Jiang L., Ravel J. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000800 Genomic DNA. Translation: ABV18180.1.
RefSeq	YP_001465092.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5588019.
GenomeReviews	Gene locus EcE24377A_4113 in contig CP000800_GR.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00821. [Family] [Alignment] [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
ProDom	PD021849. SecB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00809. secB. 1 hit.
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

SECB_ECO24

Accession

Primary (citable) accession number: A7ZTG3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	October 23, 2007
Last modified:	June 10, 2008
This is version 6 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)