Reviewed, UniProtKB/Swiss-Prot Q6RYT0 (F16P_DICDI)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase
      Short name=FBPase
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase

Gene names

Name:	fbp
ORF Names:	DDB_0216231

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
Pathway	Carbohydrate biosynthesis; gluconeogenesis.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 346	346	Fructose-1,6-bisphosphatase
Sites
	Active site	272	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6RYT0-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2F1A15EEAC62DE39	FASTA	346	38,204
	10 20 30 40 50 60 MSSNNLITLH RWLLSDTHKN MENKLEMANL FSGIALACKI TNNAIKRAGF ESNFGLAGIT 70 80 90 100 110 120 NVHSEDVKKL DVIANDAFKM ALKSTREVFC MVSEEEDSII PVSQSQAGKY VVAFDPLDGS 130 140 150 160 170 180 SNLDCNVSVG SIFSIWPKAS KDHNYSNDDV LRKGRDMTAA GYALYGSATM LVLTFGQGVY 190 200 210 220 230 240 GFTLDNHIGE FVLTHVEMRI RTKGSIYSIN EGNSVFWDKA TQEYVKAIKS GADGRAPYSS 250 260 270 280 290 300 RYIGSMVSDI HRTLLYGGIF MYPGDTKSPN GKLRYLYEVA PLSFIMEQAA GKSTNGSSPC 310 320 330 340 LDMIPKSIHE RVPVFMGSPA CIDELLAFQK KFNHNHSTTS QHEKDN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A first glimpse into the pattern and scale of gene transfer in Apicomplexa." Huang J., Mullapudi N., Sicheritz-Ponten T., Kissinger J.C. Int. J. Parasitol. 34:265-274(2004) [PubMed: 15003488] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY485279 Genomic DNA. Translation: AAS48589.1. AAFI02000005 Genomic DNA. Translation: EAL72768.1.
RefSeq	XP_646323.1.
3D structure databases
HSSP	HSSP built from PDB template 1LEV based on UniProtKB P00636.
ModBase	Search...
Genome annotation databases
GeneID	3397839.
KEGG	ddi:DDB_0216231.
Organism-specific databases
dictyBase	DDB0216231. fbp.
Family and domain databases
InterPro	IPR000146. In_FB_phphtase. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. FBPHPHTASE. PR00377. INFBPHPHTASE.
ProDom	PD001491. In_FB_phphtase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00124. FBPASE. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

F16P_DICDI

Accession

Primary (citable) accession number: Q6RYT0
Secondary accession number(s): Q55D08

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	July 5, 2004
Last modified:	September 23, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)