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Reviewed, UniProtKB/Swiss-Prot O06005 (AAPA_BACSU)

Last modified November 25, 2008. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Amino-acid permease aapA
Gene names
Name: aapA
Ordered Locus Names: BSU27090
OrganismBacillus subtilis [Complete proteome] [HAMAP]
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Probable amino-acid or metabolite transport protein.

Subcellular location

Cell membrane; Multi-pass membrane proteinPotential.

Sequence similarities

Belongs to the amino acid-polyamine-organocation (APC) superfamily.

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Ontologies

Keywords

   Biological processAmino-acid transport
Transport
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processamino acid transport

Inferred from electronic annotation. Source: InterPro

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: InterPro

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionamino acid transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 459459Amino-acid permease aapA
PRO_0000054184

Regions

Transmembrane27 – 4721 Potential
Transmembrane48 – 6821 Potential
Transmembrane96 – 11621 Potential
Transmembrane134 – 15421 Potential
Transmembrane160 – 18021 Potential
Transmembrane209 – 22921 Potential
Transmembrane252 – 27221 Potential
Transmembrane279 – 29921 Potential
Transmembrane343 – 36321 Potential
Transmembrane366 – 38621 Potential
Transmembrane410 – 43021 Potential
Transmembrane435 – 45521 Potential

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Sequences

Sequence LengthMass (Da)Tools
O06005-1 [UniParc].

Last modified July 1, 1997. Version 1.
Checksum: BA01F5871977C44F

FASTA45950,651
        10         20         30         40         50         60 
MIGNSSKDNF GQQQKLSRGL KNRHIQLMAI GGAIGTGLFL GSGKSIHFAG PSILFAYLIT 

        70         80         90        100        110        120 
GVFCFFIIRS LGELLLSNAG YHSFVDFVRD YLGNMAAFIT GWTYWFCWIS LAMADLTAVG 

       130        140        150        160        170        180 
IYTQYWLPDV PQWLPGLLAL IILLIMNLAT VKLFGELEFW FALIKVIAIL ALIVTGILLI 

       190        200        210        220        230        240 
AKGFSAASGP ASLNNLWSHG GMFPNGWHGF ILSFQMVVFA FVGIELVGLT AGETENPQKV 

       250        260        270        280        290        300 
IPKAINQIPV RILLFYVGAL FVIMCIYPWN VLNPNESPFV QVFSAVGIVV AASLINFVVL 

       310        320        330        340        350        360 
TSAASAANSA LFSTSRMVYS LAKDHHAPGL LKKLTSSNVP SNALFFSSIA ILIGVSLNYL 

       370        380        390        400        410        420 
MPEQVFTLIT SVSTICFIFI WGITVICHLK YRKTRQHEAK ANKFKMPFYP LSNYLTLAFL 

       430        440        450 
AFILVILALA NDTRIALFVT PVWFVLLIIL YKVQTQQRT

« Hide

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References

« Hide 'large scale' references
[1]"A 23911 bp region of the Bacillus subtilis genome comprising genes located upstream and downstream of the lev operon."
Parro V., San Roman M., Galindo I., Purnelle B., Bolotin A., Sorokin A., Mellado R.P.
Microbiology 143:1321-1326(1997) [PubMed: 9141695] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

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Cross-references

Sequence databases

X92868 Genomic DNA. Translation: CAA63459.1.
Z99117 Genomic DNA. Translation: CAB14651.1.
PIRB69580.
RefSeqNP_390587.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID937231.
GenomeReviewsGene locus BSU27090 in contig AL009126_GR.
KEGGbsu:BSU27090.
NMPDRfig|224308.1.peg.2712.

Organism-specific databases

SubtiListBG12556. aapA. [Micado]
CMRSearch...

Phylogenomic databases

HOGENOMO06005.

Enzyme and pathway databases

BioCycBSUB224308:BSU2705-MON.

Family and domain databases

InterProIPR002293. AA/rel_permease1.
IPR004840. Amoino_acid_permease_CS.
IPR004841. Permease_region.
[Graphical view]
PANTHERPTHR11785. AA/rel_permease1. 1 hit.
PfamPF00324. AA_permease. 1 hit.
[Graphical view]
PIRSFPIRSF006060. AA_transporter. 1 hit.
PROSITEPS00218. AMINO_ACID_PERMEASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameAAPA_BACSU
AccessionPrimary (citable) accession number: O06005
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 1, 1997
Last modified: November 25, 2008
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents