Reviewed, UniProtKB/Swiss-Prot O13340 (CARP_PODAN)

Names and origin

Protein names

Recommended name:
    Podosporapepsin
    EC=3.4.23.-

Gene names

Name:

PAPA

Organism

Podospora anserina

Taxonomic identifier

5145 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Sordariales › Lasiosphaeriaceae › Podospora

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Induction	Expressed under carbon starvation conditions.
Sequence similarities	Belongs to the peptidase A1 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Aspartyl protease Hydrolase Protease
PTM	Cleavage on pair of basic residues Glycoprotein Zymogen
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Propeptide	29 – 91	63	Activation peptide By similarity		PRO_0000025877
	Chain	92 – 425	334	Podosporapepsin		PRO_0000025878
Sites
	Active site	126	1	By similarity
	Active site	310	1	By similarity
Amino acid modifications
	Glycosylation	184	1	N-linked (GlcNAc...) Potential
	Glycosylation	273	1	N-linked (GlcNAc...) Potential
	Glycosylation	370	1	N-linked (GlcNAc...) Potential
	Disulfide bond	346 ↔ 381		By similarity

Sequences

	Sequence		Length	Mass (Da)
	O13340-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: DA66CAA215183214	FASTA	425	45,921
	10 20 30 40 50 60 MVSLTDLFLA SLLVPTSPWL CLPPRIDTID QRGGRVTLKQ VRNPRGHKAF NPARATYRTF 70 80 90 100 110 120 LKYGVPAPDY IKKAVAHIDE EQEEAFARIK RDTGSAAAIP INEVDIAYVT PVTIGTPPQT 130 140 150 160 170 180 LMLDLDTGSS DLWVFSSLTP SNQVRGQEIY SPTKSSTSKL LSGHTWSIRY GDGSGSRGTV 190 200 210 220 230 240 YTDNFTIGGL EVKSQAVQAA LEVSSMLTQE QSLDGLVGLG FSALNTVRPS SQLTFFDNAR 250 260 270 280 290 300 PNLDEEVFTA DLKYHATGSY DFGFIDSKKY AGNITYTAVQ QSPGYWTHSL SGYSVGSGAF 310 320 330 340 350 360 QASQISGISD TGTTLLYLPT AIVTAYYRQV QGAQNSQYYG GYVFPCSSTL PTFTFGIEGA 370 380 390 400 410 420 RFTIPASYIN YTRISPTSTT CYGGLQSSSG LGINIFGDVA LKRAFVVFSG TNPPRIGFAI KPLAS

References

[1]	"Characterization of a gene from the filamentous fungus Podospora anserina encoding an aspartyl protease induced upon carbon starvation." Paoletti M., Clave C., Begueret J. Gene 210:45-52(1998) [PubMed: 9524217] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF016054 Genomic DNA. Translation: AAC49997.1.
PIR	JC6557.
3D structure databases
HSSP	HSSP built from PDB template 1GVU based on UniProtKB P11838.
ModBase	Search...
Protein family/group databases
MEROPS	A01.044.
Family and domain databases
InterPro	IPR001969. Pept_Asp_AS. IPR009007. Pept_Aspartc_cat. IPR001461. Peptidase_A1. [Graphical view]
Gene3D	G3DSA:2.40.70.10. Pept_Aspartc_cat. 1 hit.
PANTHER	PTHR13683. Peptidase_A1. 1 hit.
Pfam	PF00026. Asp. 1 hit. [Graphical view]
PRINTS	PR00792. PEPSIN.
PROSITE	PS00141. ASP_PROTEASE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CARP_PODAN

Accession

Primary (citable) accession number: O13340

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	January 1, 1998
Last modified:	November 25, 2008
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)