Reviewed, UniProtKB/Swiss-Prot O24989 (Y189_HELPY)

Names and origin

Protein names

Recommended name:
    UPF0114 protein HP_0189

Gene names

Ordered Locus Names:

HP_0189

Organism

Helicobacter pylori (Campylobacter pylori) [Complete proteome] [HAMAP]

Taxonomic identifier

210 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane proteinPotential.
Sequence similarities	Belongs to the UPF0114 family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 177	177	UPF0114 protein HP_0189
Regions
	Transmembrane	15 – 35	21	Potential
	Transmembrane	54 – 74	21	Potential
	Transmembrane	145 – 165	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	O24989-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 782125BD0BA303DD	FASTA	177	19,828
	10 20 30 40 50 60 MLEKLIERVL FATRWLLAPL CIAMSLVLVV LGYVFMKELW HMLSHLNTIS ETDLVLSALG 70 80 90 100 110 120 LVDLLFMAGL VLMVLLASYE SFVSKLDKVD ASEITWLKHT DFNALKLKVS LSIVAISAIF 130 140 150 160 170 LLKRYMSLED VLSSIPKDTP LSHNPIFWQV VIHLVFVCSA LLAAVTNNIA FSQNKAH

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000511 Genomic DNA. Translation: AAD07256.1.
PIR	E64543.
RefSeq	NP_206988.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:3137N.
Genome annotation databases
GeneID	898953.
GenomeReviews	Gene locus HP_0189 in contig AE000511_GR.
KEGG	hpy:HP0189.
NMPDR	fig|85962.1.peg.186.
TIGR	HP_0189.
Phylogenomic databases
HOGENOM	O24989.
Family and domain databases
HAMAP	MF_00143. [Tree]
InterPro	IPR005134. UPF0114. [Graphical view]
Pfam	PF03350. UPF0114. 1 hit. [Graphical view]
ProDom	PD011070. UPF0114. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00645. HI0507. 1 hit.
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

Y189_HELPY

Accession

Primary (citable) accession number: O24989

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	January 1, 1998
Last modified:	July 22, 2008
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)