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Reviewed, UniProtKB/Swiss-Prot O34450 (NAGA_BACSU)

Last modified November 25, 2008. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase
Gene names
Name: nagA
Ordered Locus Names: BSU35010
OrganismBacillus subtilis [Complete proteome] [HAMAP]
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Catalytic activity

N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate.

Pathway

Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 4/5.

Sequence similarities

Belongs to the nagA family.

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Ontologies

Keywords

   Biological processCarbohydrate metabolism
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome

Gene Ontology (GO)

   Biological processN-acetylglucosamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionN-acetylglucosamine-6-phosphate deacetylase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396N-acetylglucosamine-6-phosphate deacetylase
PRO_0000170914

Secondary structure

1 .................................................................................... 396
Helix Strand Turn

Details...

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Sequences

Sequence LengthMass (Da)Tools
O34450-1 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 852D53C71BAD6F54

FASTA39642,622
        10         20         30         40         50         60 
MAESLLIKDI AIVTENEVIK NGYVGINDGK ISTVSTERPK EPYSKEIQAP ADSVLLPGMI 

        70         80         90        100        110        120 
DIHIHGGYGA DTMDASFSTL DIMSSRLPEE GTTSFLATTI TQEHGNISQA LVNAREWKAA 

       130        140        150        160        170        180 
EESSLLGAEL LGIHLEGPFV SPKRAGAQPK EWIRPSDVEL FKKWQQEAGG LIKIVTLAPE 

       190        200        210        220        230        240 
EDQHFELIRH LKDESIIASM GHTDADSALL SDAAKAGASH MTHLYNAMSP FHHREPGVIG 

       250        260        270        280        290        300 
TALAHDGFVT ELIADGIHSH PLAAKLAFLA KGSSKLILIT DSMRAKGLKD GVYEFGGQSV 

       310        320        330        340        350        360 
TVRGRTALLS DGTLAGSILK MNEGARHMRE FTNCSWTDIA NITSENAAKQ LGIFDRKGSV 

       370        380        390 
TVGKDADLVI VSSDCEVILT ICRGNIAFIS KEADQI

« Hide

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References

« Hide 'large scale' references
[1]"Nucleotide sequence of the 300-304 chromosomal segment of Bacillus subtilis."
Lazarevic V., Soldo B., Rivolta C., Reynolds S., Mauel C., Karamata D.
Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AF017113 Genomic DNA. Translation: AAC67285.1.
Z99121 Genomic DNA. Translation: CAB15506.1.
PIRA69664.
RefSeqNP_391381.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1UN7X-ray2.05A/B1-396[»]
2VHLX-ray2.05A/B1-396[»]
SMRO34450. Positions 3-394.
ModBaseSearch...

Genome annotation databases

GeneID936621.
GenomeReviewsGene locus BSU35010 in contig AL009126_GR.
KEGGbsu:BSU35010.
NMPDRfig|224308.1.peg.3507.

Organism-specific databases

SubtiListBG12630. nagA. [Micado]
CMRSearch...

Phylogenomic databases

HOGENOMO34450.

Enzyme and pathway databases

BioCycBSUB224308:BSU3498-MON.

Family and domain databases

InterProIPR006680. Amidohydro_1.
IPR003764. GlcNAc_6-P_deAcase.
IPR002197. HTH_Fis.
[Graphical view]
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
PRINTSPR01590. HTHFIS.
TIGRFAMsTIGR00221. nagA. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameNAGA_BACSU
AccessionPrimary (citable) accession number: O34450
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: November 25, 2008
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents