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Reviewed, UniProtKB/Swiss-Prot O43053 (ALG6_SCHPO)

Last modified December 16, 2008. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
    EC=2.4.1.-
Alternative name(s):
    Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase
    Asparagine-linked glycosylation protein 6
Gene names
Name: alg6
ORF Names: SPBC342.01c, SPBC3F6.06c
OrganismSchizosaccharomyces pombe (Fission yeast) [Complete proteome]
Taxonomic identifier4896 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

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Protein attributes

Sequence length506 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol By similarity.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane proteinPotential.

Sequence similarities

Belongs to the ALG6/ALG8 glucosyltransferase family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 506506Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
PRO_0000174160

Regions

Transmembrane25 – 4521 Potential
Transmembrane133 – 15321 Potential
Transmembrane189 – 20921 Potential
Transmembrane212 – 23221 Potential
Transmembrane248 – 26821 Potential
Transmembrane318 – 33821 Potential
Transmembrane343 – 36321 Potential
Transmembrane383 – 40321 Potential
Transmembrane437 – 45721 Potential
Transmembrane465 – 48521 Potential

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Sequences

Sequence LengthMass (Da)Tools
O43053-1 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 0CD8ACC78BF49D6B

FASTA50659,203
        10         20         30         40         50         60 
MLSEFENGAP VQQFVSRFRS YSSKFLFFPC LIMSLVFMQW LISIGPYSGY NTPPMYGDFE 

        70         80         90        100        110        120 
AQRHWMELTL HTPVSQWYFR DLQWWGLDYP PLTAYVSWFF GIIGHYFFNP EWFADVTSRG 

       130        140        150        160        170        180 
FESLELKLFM RSTVIASHLL ILVPPLMFYS KWWSRRIPNF VDRNASLIMV LFQPALLLID 

       190        200        210        220        230        240 
HGHFQYNCVM LGLVMYAIAN LLKNQYVAAT FFFCLALTFK QMALYFAPPI FFYLLGTCVK 

       250        260        270        280        290        300 
PKIRFSRFIL LSVTVVFTFS LILFPWIYMD YKTLLPQILH RVFPFARGLW EDKVANFWCT 

       310        320        330        340        350        360 
LNTVFKIREV FTLHQLQVIS LIFTLISILP SCVILFLYPR KRLLALGFAS ASWGFFLFSF 

       370        380        390        400        410        420 
QVHEKSVLLP LLPTSILLCH GNITTKPWIA LANNLAVFSL WPLLKKDGLG LQYFTLVLMW 

       430        440        450        460        470        480 
NWIGDMVVFS KNVLFRFIQL SFYVGMIVIL GIDLFIPPPS RYPDLWVILN VTLSFAGFFT 

       490        500 
IYLWTLGRLL HISSKLSTDL RNKKEA

« Hide

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References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 38366 / 972.

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Cross-references

Sequence databases

CU329671 Genomic DNA. Translation: CAA17695.1.
PIRT40396.
RefSeqNP_596744.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2540993.
KEGGspo:SPBC342.01c.
NMPDRfig|4896.1.peg.2610.

Organism-specific databases

GeneDB_SpombeSPBC342.01c.

Enzyme and pathway databases

BioCycSPOM-XXX-01:SPOM-XXX-01-004905-MON.

Gene expression databases

ArrayExpressO43053.

Family and domain databases

InterProIPR004856. Alg6_Alg8.
[Graphical view]
PANTHERPTHR12413. Alg6_Alg8. 1 hit.
PfamPF03155. Alg6_Alg8. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameALG6_SCHPO
AccessionPrimary (citable) accession number: O43053
Secondary accession number(s): Q9UUC4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: June 1, 1998
Last modified: December 16, 2008
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents