Reviewed, UniProtKB/Swiss-Prot O49279 (FBX3_ARATH)

Names and origin

Protein names

Recommended name:
    F-box only protein 3

Gene names

Name:	FBX3
Ordered Locus Names:	At1g76920
ORF Names:	F22K20.2

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Pathway	Protein modification; protein ubiquitination.
Subunit structure	Part of a SCF (SKP1-cullin-F-box) protein ligase complex By similarity.
Sequence similarities	Contains 1 F-box domain.

Ontologies

Keywords
Biological process	Ubl conjugation pathway
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
AT4g34210	O49484	2	EBI-591174,EBI-401185
SKP1A	Q39255	2	EBI-591174,EBI-532357
SKP1B	Q9FHW7	3	EBI-591174,EBI-604076

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 374	374	F-box only protein 3		PRO_0000273536
Regions
	Domain	3 – 48	46	F-box

Sequences

	Sequence		Length	Mass (Da)
	O49279-1 [UniParc]. Last modified June 1, 1998. Version 1. Checksum: 1D8584587C616173	FASTA	374	42,494
	10 20 30 40 50 60 MESSPVNCLP PDSLHQIFSS LPIRDIMICR SVCKFFNQLL TSQCFIEIIS TRPPLNLLAL 70 80 90 100 110 120 RPPHHHHSHR HSGNGHATNI RPYIHVYDPE QNQWFRFNLD FLPFRSPQPV ASSSGLIYLW 130 140 150 160 170 180 GDSIDLAESS KSLVACNPLT RQFKVLPQLG SAWSRHGTVL VDSVNRVMVL TELAALYYSG 190 200 210 220 230 240 TVVANQWLKF SSNLPSKPRS PVLMSSSVFA LCDVGSPWRS QWKLFSCKLT NLTITHTNWV 250 260 270 280 290 300 CLEKHEWGDI FDIIKRPRLL RGNGDSKLLM IGGLKSTFSL NPACSTILIL RLDLESLEWE 310 320 330 340 350 360 EAGRMPLEMY RGFQESSKFK VFGGGDRVYF SAKRMGKLAM WDCWQGWRWI EGVPGYADGL 370 CRGFVFDAKL TLMP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[3]	"Full-length cDNA from Arabidopsis thaliana." Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[4]	"F-box proteins in Arabidopsis." Xiao W., Jang J.-C. Trends Plant Sci. 5:454-457(2000) [PubMed: 11077244] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC002291 Genomic DNA. Translation: AAC00632.1. AY065102 mRNA. Translation: AAL38278.1. BT008455 mRNA. Translation: AAP37814.1. AY085473 mRNA. Translation: AAM62699.1.
PIR	A96798.
RefSeq	NP_565142.1.
UniGene	At.21630
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	O49279. 9 interactions.
Proteomic databases
ProMEX	O49279.
Genome annotation databases
GeneID	844027.
GenomeReviews	Gene locus AT1G76920 in contig CT485782_GR.
KEGG	ath:AT1G76920.
NMPDR	fig|3702.1.peg.7224.
Organism-specific databases
TAIR	At1g76920.
Family and domain databases
InterPro	IPR001810. F-box. IPR011498. Kelch_2. [Graphical view]
Pfam	PF00646. F-box. 1 hit. PF07646. Kelch_2. 2 hits. [Graphical view]
SMART	SM00256. FBOX. 1 hit. [Graphical view]
PROSITE	PS50181. FBOX. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FBX3_ARATH

Accession

Primary (citable) accession number: O49279

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	June 1, 1998
Last modified:	December 16, 2008
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)