Reviewed, UniProtKB/Swiss-Prot O81053 (FUT2_ARATH)

Names and origin

Protein names

Recommended name:
    Fucosyltransferase 2
      Short name=AtFUT2
    EC=2.4.1.-

Gene names

Name:	FUT2
Ordered Locus Names:	At2g03210
ORF Names:	T18E12.12

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	539 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May be involved in cell wall biosynthesis. May act as a fucosyltransferase.
Pathway	Protein modification; protein glycosylation.
Subcellular location	Golgi apparatus › Golgi stack membrane; Single-pass type II membrane proteinBy similarity. Note= Membrane-bound form in trans cisternae of Golgi By similarity.
Tissue specificity	Expressed in roots, stems, leaves, flowers, siliques and seedlings. Ref.3
Sequence similarities	Belongs to the glycosyltransferase 37 family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall biogenesis Inferred from electronic annotation. Source: InterPro
Cellular component	Golgi apparatus Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	galactoside 2-alpha-L-fucosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 539	539	Fucosyltransferase 2		PRO_0000193911
Regions
	Topological domain	1 – 5	5	Cytoplasmic Potential
	Transmembrane	6 – 26	21	Signal-anchor for type II membrane protein Potential
	Topological domain	27 – 539	513	Lumenal Potential
Amino acid modifications
	Glycosylation	44	1	N-linked (GlcNAc...) Potential
	Glycosylation	231	1	N-linked (GlcNAc...) Potential
	Glycosylation	482	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	O81053-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 5AEA7F45847DC67C	FASTA	539	61,571
	10 20 30 40 50 60 MRITEILALF MVLVPVSLVI VAMFGYDQGN GFVQASRFIT MEPNVTSSSD DSSLVQRDQE 70 80 90 100 110 120 QKDSVDMSLL GGLLVSGFKK ESCLSRYQSY LYRKASPYKP SLHLLSKLRA YEELHKRCGP 130 140 150 160 170 180 GTRQYTNAER LLKQKQTGEM ESQGCKYVVW MSFSGLGNRI ISIASVFLYA MLTDRVLLVE 190 200 210 220 230 240 GGEQFADLFC EPFLDTTWLL PKDFTLASQF SGFGQNSAHC HGDMLKRKLI NESSVSSLSH 250 260 270 280 290 300 LYLHLAHDYN EHDKMFFCEE DQNLLKNVPW LIMRTNNFFA PSLFLISSFE EELGMMFPEK 310 320 330 340 350 360 GTVFHHLGRY LFHPSNQVWG LITRYYQAYL AKADERIGLQ IRVFDEKSGV SPRVTKQIIS 370 380 390 400 410 420 CVQNENLLPR LSKGEEQYKQ PSEEELKLKS VLVTSLTTGY FEILKTMYWE NPTVTRDVIG 430 440 450 460 470 480 IHQPSHEGHQ QTEKLMHNRK AWAEMYLLSL TDKLVISAWS TFGYVAQGLG GLRAWILYKQ 490 500 510 520 530 ENQTNPNPPC GRAMSPDPCF HAPPYYDCKA KKGTDTGNVV PHVRHCEDIS WGLKLVDNF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations." Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P. Plant Biotechnol. J. 4:317-324(2006) [PubMed: 17147637] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[3]	"Characterization of a family of Arabidopsis genes related to xyloglucan fucosyltransferase1." Sarria R., Wagner T.A., O'Neill M.A., Faik A., Wilkerson C.G., Keegstra K., Raikhel N.V. Plant Physiol. 127:1595-1606(2001) [PubMed: 11743104] [Abstract] Cited for: IDENTIFICATION AS A PUTATIVE FUCOSYLTRANSFERASE, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AC005313 Genomic DNA. Translation: AAC34481.1. DQ446460 mRNA. Translation: ABE65797.1.
PIR	T02705.
RefSeq	NP_178420.1.
UniGene	At.52617
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	814850.
GenomeReviews	Gene locus AT2G03210 in contig CT485783_GR.
KEGG	ath:AT2G03210.
NMPDR	fig|3702.1.peg.7918.
Organism-specific databases
TAIR	At2g03210.
Gene expression databases
ArrayExpress	O81053.
Family and domain databases
InterPro	IPR004938. XG_FTase. [Graphical view]
Pfam	PF03254. XG_FTase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FUT2_ARATH

Accession

Primary (citable) accession number: O81053
Secondary accession number(s): Q1PFA3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	November 1, 1998
Last modified:	November 25, 2008
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)