Reviewed, UniProtKB/Swiss-Prot O85388 (RS3_COXBU)

Names and origin

Protein names

Recommended name:
    30S ribosomal protein S3

Gene names

Name:	rpsC
Ordered Locus Names:	CBU_0244

Organism

Coxiella burnetii [Complete proteome] [HAMAP]

Taxonomic identifier

777 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation By similarity.
Subunit structure	Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14 By similarity.
Sequence similarities	Belongs to the ribosomal protein S3P family. Contains 1 KH type-2 domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 227	227	30S ribosomal protein S3 HAMAP MF_01309		PRO_0000130109
Regions
	Domain	39 – 107	69	KH type-2
Experimental info
	Sequence conflict	60	1	P → T in AAD09929. Ref.2
	Sequence conflict	68 – 74	7	IHSARPG → NPFLLRP in AAD09929. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	O85388-1 [UniParc]. Last modified May 9, 2003. Version 2. Checksum: B79F899F8C59B82E	FASTA	227	25,627
	10 20 30 40 50 60 MGQKVNPVGM RIGITRDWTS NWYADKKDFA DRLNEDLNVR QLLQKRLKGA AVSRIQIERP 70 80 90 100 110 120 ARNAKIIIHS ARPGVIIGKK GGEIEALRDE IFKVMKVPVH ITIEEVRKPE LDAKLVAENI 130 140 150 160 170 180 AQQLERRVMF RRAMKRAVQN TLRQGALGVK ISVSGRLGGA EIARTEWYRE GRVPLHTFRA 190 200 210 220 DIDYATASAK TTYGIIGVKV WIFKGEVHAP KPQAEEAAPQ ETEEEVK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. , Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F. Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493.
[2]	"Physical and genetic map of the obligate intracellular bacterium Coxiella burnetii." Willems H., Jaeger C., Baljer G. J. Bacteriol. 180:3816-3822(1998) [PubMed: 9683477] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-74. Strain: Nine Mile phase I / RSA 493.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016828 Genomic DNA. Translation: AAO89802.1. AF064946 Genomic DNA. Translation: AAD09929.1.
RefSeq	NP_819288.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1208125.
GenomeReviews	Gene locus CBU_0244 in contig AE016828_GR.
KEGG	cbu:CBU_0244.
NMPDR	fig|227377.1.peg.232.
TIGR	CBU_0244.
Phylogenomic databases
HOGENOM	O85388.
Enzyme and pathway databases
BioCyc	CBUR227377:CBU_0244-MON.
Family and domain databases
HAMAP	MF_01309. [Tree]
InterPro	IPR004087. KH. IPR015946. KH-like_a/b. IPR004044. KH_type_2. IPR005704. Ribosomal_S3_bac. IPR001351. Ribosomal_S3_C. IPR008282. Ribosomal_S3_N. [Graphical view]
Gene3D	G3DSA:3.30.300.20. KH_prok. 1 hit. G3DSA:3.30.1140.32. Ribosomal_S3_C. 1 hit.
Pfam	PF07650. KH_2. 1 hit. PF00189. Ribosomal_S3_C. 1 hit. PF00417. Ribosomal_S3_N. 1 hit. [Graphical view]
SMART	SM00322. KH. 1 hit. [Graphical view]
TIGRFAMs	TIGR01009. rpsC_bact. 1 hit.
PROSITE	PS50823. KH_TYPE_2. 1 hit. PS00548. RIBOSOMAL_S3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS3_COXBU

Accession

Primary (citable) accession number: O85388

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 9, 2003
Last modified:	November 25, 2008
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)