Reviewed, UniProtKB/Swiss-Prot P00244 (FER1_APHFL)

Names and origin

Protein names	Recommended name:     Ferredoxin-1 Alternative name(s):     Ferredoxin I
Organism	Aphanizomenon flos-aquae
Taxonomic identifier	1176 [NCBI]
Taxonomic lineage	Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Aphanizomenon

Protein attributes

Sequence length	98 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Cofactor	Binds 1 2Fe-2S cluster.
Sequence similarities	Belongs to the 2Fe2S plant-type ferredoxin family. Contains 1 2Fe-2S ferredoxin-type domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Ligand	2Fe-2S Iron Iron-sulfur Metal-binding
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Initiator methionine	1	1	Removed
	Chain	2 – 98	97	Ferredoxin-1
Regions
	Domain	4 – 95	92	2Fe-2S ferredoxin-type
Sites
	Metal binding	41	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	46	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	49	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	79	1	Iron-sulfur (2Fe-2S) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P00244-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 44D9A6160F408353	FASTA	98	10,515
	10 20 30 40 50 60 MATYKVTLID AEGTTTTIDC PDDTYILDAA EEAGLDLPYS CRAGACSTCA GKLVTGTIDQ 70 80 90 SDQSFLDDDQ VEAGYVLTCV AYPTSDVTIE THKEEDLY

References

[1]	"Amino acid sequence of ferredoxin from Aphanizomenon flos-aquae." Lee I.S., Hase T., Matsubara H., Ho K.K., Krogmann D.W. Biochim. Biophys. Acta 744:53-56(1983) Cited for: PROTEIN SEQUENCE OF 2-98.

Cross-references

Sequence databases
PIR	FEFZ1. A00248.
3D structure databases
HSSP	HSSP built from PDB template 4FXC based on UniProtKB P00246.
SMR	P00244. Positions 2-98.
ModBase	Search...
Family and domain databases
InterPro	IPR006058. 2Fe2S_fd_BS. IPR012675. b-grasp_ferredoxin-like. IPR010241. Fdx_pln. IPR001041. Ferredoxin. [Graphical view]
Gene3D	G3DSA:3.10.20.30. Ferredoxin_fold. 1 hit.
Pfam	PF00111. Fer2. 1 hit. [Graphical view]
TIGRFAMs	TIGR02008. fdx_plant. 1 hit.
PROSITE	PS00197. 2FE2S_FER_1. 1 hit. PS51085. 2FE2S_FER_2. 1 hit. [Graphical view]
ProDom	P00244. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

FER1_APHFL

Accession

Primary (citable) accession number: P00244

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 21, 1986
Last sequence update:	January 23, 2007
Last modified:	July 22, 2008
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)