Reviewed, UniProtKB/Swiss-Prot P04650 (RL39_YEAST)

Names and origin

Protein names

Recommended name:
    60S ribosomal protein L39
Alternative name(s):
    L46
    YL40

Gene names

Name:	RPL39
Synonyms:	RPL46, SPB2
Ordered Locus Names:	YJL189W
ORF Names:	J0360

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	51 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the ribosomal protein L39e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Ref.3 Traceable author statement. Source: SGD
Cellular component	cytosolic large ribosomal subunit Ref.3 Traceable author statement. Source: SGD
Molecular function	structural constituent of ribosome Ref.3 Traceable author statement. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed
	Chain	2 – 51	50	60S ribosomal protein L39		PRO_0000127044

Sequences

	Sequence		Length	Mass (Da)
	P04650-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: FE518D8B3949C163	FASTA	51	6,342
	10 20 30 40 50 MAAQKSFRIK QKMAKAKKQN RPLPQWIRLR TNNTIRYNAK RRNWRRTKMN I

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed." Leer R.J., van Raamsdonk-Duin M.M.C., Kraakman P., Mager W.H., Planta R.J. Nucleic Acids Res. 13:701-709(1985) [PubMed: 4000930] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed: 9559554] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"The action of N-terminal acetyltransferases on yeast ribosomal proteins." Arnold R.J., Polevoda B., Reilly J.P., Sherman F. J. Biol. Chem. 274:37035-37040(1999) [PubMed: 10601260] [Abstract] Cited for: CLEAVAGE OF INITIATOR METHIONINE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X01963 Genomic DNA. Translation: CAA25999.1. Z49464 Genomic DNA. Translation: CAA89483.1.
PIR	R6BY46. B23082.
RefSeq	NP_012346.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4522N.
IntAct	P04650.
Proteomic databases
PeptideAtlas	P04650.
Genome annotation databases
Ensembl	YJL189W. Saccharomyces cerevisiae. [Contig view]
GeneID	853250.
GenomeReviews	Gene locus YJL189W in contig Y13136_GR.
KEGG	sce:YJL189W.
NMPDR	fig|4932.3.peg.3310.
Organism-specific databases
CYGD	YJL189w.
SGD	S000003725. RPL39.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	P04650.
Gene expression databases
GermOnline	YJL189W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000077. Ribosomal_L39. [Graphical view]
Gene3D	G3DSA:1.10.1620.10. Ribosomal_L39. 1 hit.
PANTHER	PTHR19970. Ribosomal_L39. 1 hit.
Pfam	PF00832. Ribosomal_L39. 1 hit. [Graphical view]
ProDom	PD007914. Ribosomal_L39. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00051. RIBOSOMAL_L39E. 1 hit. [Graphical view]
BLOCKS	Search...
ProtoNet	Search...
Other Resources
LinkHub	P04650.
NextBio	973493.

Entry information

Entry name

RL39_YEAST

Accession

Primary (citable) accession number: P04650

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 1987
Last sequence update:	January 23, 2007
Last modified:	November 4, 2008
This is version 68 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)