Reviewed, UniProtKB/Swiss-Prot P22929 (CARP_SACFI)

Names and origin

Protein names

Recommended name:
    Acid protease
    EC=3.4.23.-

Gene names

Name:

PEP1

Organism

Saccharomycopsis fibuligera (Yeast)

Taxonomic identifier

4944 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycopsidaceae › Saccharomycopsis

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the peptidase A1 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Aspartyl protease Hydrolase Protease
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Signal peptide	1 – 18	18	Potential
	Chain	19 – 390	372	Acid protease
Sites
	Active site	93	1	By similarity
	Active site	282	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P22929-1 [UniParc]. Last modified August 1, 1991. Version 1. Checksum: 350BF97116C54796	FASTA	390	41,263
	10 20 30 40 50 60 MLFSKSLLLS VLASLSFAAP VEKREKTLTL DFDVKRISSK AKNVTVASSP GFRRNLRAAS 70 80 90 100 110 120 DAGVTISLEN EYSFYLTTIE IGTPGQKLQV DVDTGSSDLW VPGQGTSSLY GTYDHTKSTS 130 140 150 160 170 180 YKKDRSGFSI SYGDGSSARG DWAQETVSIG GASITGLEFG DATSQDVGQG LLGIGLKGNE 190 200 210 220 230 240 ASAQSSNSFT YDNLPLKLKD QGLIDKAAYS LYLNSEDATS GSILFGGSDS SKYSGSLATL 250 260 270 280 290 300 DLVNIDDEGD STSGAVAFFV ELEGIEAGSS SITKTTYPAL LDSGTTLIYA PSSIASSIGR 310 320 330 340 350 360 EYGTYSYSYG GYVTSCDATG PDFKFSFNGK TITVPFSNLL FQNSEGDSEC LVGVLSSGSN 370 380 390 YYILGDAFLR SAYVYYDIDN SQVGIAQAKY

References

[1]	"Nucleotide sequence of the secretable acid protease gene PEPI in the yeast Saccharomycopsis fibuligera." Hirata D., Fukui S., Yamashita I. Agric. Biol. Chem. 52:2647-2649(1988) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	D00313 Genomic DNA. Translation: BAA00215.1.
PIR	JT0334.
3D structure databases
HSSP	HSSP built from PDB template 2REN based on UniProtKB P00797.
ModBase	Search...
Family and domain databases
InterPro	IPR001969. Pept_Asp_AS. IPR009007. Pept_Aspartc_cat. IPR001461. Peptidase_A1. [Graphical view]
Gene3D	G3DSA:2.40.70.10. Pept_Aspartc_cat. 2 hits.
PANTHER	PTHR13683. Peptidase_A1. 1 hit.
Pfam	PF00026. Asp. 1 hit. [Graphical view]
PRINTS	PR00792. PEPSIN.
PROSITE	PS00141. ASP_PROTEASE. 2 hits. [Graphical view]
ProDom	P22929. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

CARP_SACFI

Accession

Primary (citable) accession number: P22929

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	August 1, 1991
Last modified:	July 22, 2008
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)