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Reviewed, UniProtKB/Swiss-Prot P33690 (COMQ_BACSU)

Last modified July 22, 2008. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Competence regulatory protein comQ
Gene names
Name: comQ
Ordered Locus Names: BSU31710
OrganismBacillus subtilis [Complete proteome] [HAMAP]
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length299 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existencePredicted.

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General annotation (Comments)

Function

Involved in the maturation of comX, part of a major quorum-sensing system that regulates the development of genetic competence.

Subcellular location

Cell membrane; Single-pass membrane proteinPotential.

Miscellaneous

The DNA sequences encoding comQ, comX and the N-terminal two-thirds of comP show a striking polymorphism, which determines the specificity of the quorum-sensing system in the different pherotypes of Bacillus.

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Ontologies

Keywords

   Biological processCompetence
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
   Technical termComplete proteome

Gene Ontology (GO)

None. [Check GOA]

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – 299299Competence regulatory protein comQ

Regions

Transmembrane148 – 16821 Potential

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Sequences

Sequence LengthMass (Da)Tools
P33690-1 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: FC82ABB37D844BA8

FASTA29934,204
        10         20         30         40         50         60 
MKEIVEQNIF NEDLSQLLYS FIDSKETFSF AESSILHYVV FGGENLDVAT RLGAGIEILI 

        70         80         90        100        110        120 
LSSDIMDDLE DEDNHHALWM KINRSESLNA ALSLYTVGLT SIYSLNNNPL IFKYVLKYVN 

       130        140        150        160        170        180 
EAMQGQHDDI TNKSKTEDES LEVIRLKCGS LIALANVAGV LLATGEYNET VERYSYYKGI 

       190        200        210        220        230        240 
IAQISGDYYV LLSGNRSDIE KNKHTLIYLY LKRLFNDASE DLLYLISHKD LYYKSLLDKE 

       250        260        270        280        290 
KFQEKLIKAG VTQYISVLLE IYKQKCISAI EQLNLDKEKK ELIKECLLSY TKGDTRCKT

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References

« Hide 'large scale' references
[1]"Sequence and properties of comQ, a new competence regulatory gene of Bacillus subtilis."
Weinrauch Y., Msadek T., Kunst F., Dubnau D.
J. Bacteriol. 173:5685-5693(1991) [PubMed: 1715859] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai)."
Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H., Duesterhoeft A., Pohl T.M., Weitzenegger T.
Microbiology 143:2769-2774(1997) [PubMed: 9274030] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[4]"Specificity and genetic polymorphism of the Bacillus competence quorum-sensing system."
Tortosa P., Logsdon L., Kraigher B., Itoh Y., Mandic-Mulec I., Dubnau D.
J. Bacteriol. 183:451-460(2001) [PubMed: 11133937] [Abstract]
Cited for: POLYMORPHISM IN COMX; COMQ AND COMP, FUNCTION.

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Cross-references

Sequence databases

M71283 Genomic DNA. Translation: AAA22323.1.
Z93932 Genomic DNA. Translation: CAB07902.1.
Z99120 Genomic DNA. Translation: CAB15159.1.
PIRA38111.
RefSeqNP_391049.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID937180.
GenomeReviewsGene locus BSU31710 in contig AL009126_GR.
KEGGbsu:BSU31710.
NMPDRfig|224308.1.peg.3174.

Organism-specific databases

SubtiListBG10379. comQ. [Micado]
CMRSearch...

Phylogenomic databases

HOGENOMP33690.

Enzyme and pathway databases

BioCycBSUB224308:BSU3166-MON.

Family and domain databases

InterProIPR017446. Polyprenyl_synth-rel.
IPR008949. Terpenoid_synth.
[Graphical view]
Gene3DG3DSA:1.10.600.10. Terpenoid_synth. 1 hit.
PANTHERPTHR12001. Polyprenyl_synt. 1 hit.
ProDomP33690.
[Graphical view] [Entries sharing at least one domain]
BLOCKSSearch...

Other Resources

ProtoNetSearch...

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Entry information

Entry nameCOMQ_BACSU
AccessionPrimary (citable) accession number: P33690
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: July 22, 2008
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents