Reviewed, UniProtKB/Swiss-Prot P39066 (ACUB_BACSU)

Names and origin

Protein names

Recommended name:
    Acetoin utilization protein acuB

Gene names

Name:	acuB
Ordered Locus Names:	BSU29700

Organism

Bacillus subtilis [Complete proteome] [HAMAP]

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Function	Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source.
Pathway	Ketone degradation; acetoin degradation.
Sequence similarities	Contains 2 CBS domains.

Ontologies

Keywords
Biological process	Acetoin catabolism Sporulation
Domain	CBS domain Repeat
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	acetoin catabolic process Inferred from electronic annotation. Source: UniProtKB-KW sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 214	214	Acetoin utilization protein acuB		PRO_0000064446
Regions
	Domain	7 – 66	60	CBS 1
	Domain	78 – 135	58	CBS 2

Sequences

	Sequence		Length	Mass (Da)
	P39066-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 3B7A964B5C95CCEF	FASTA	214	24,352
	10 20 30 40 50 60 MIVEQIMKRD VITLTKTDTL ETAICKLKEF HIRHLPVVDE ERHVIGMITD RDMKQASPSI 70 80 90 100 110 120 FEENKRSLFL TRSVDSIMKK DVVCAHPLDF VEEISAVFYE HGIGCLPVVH HQKLIGILTK 130 140 150 160 170 180 TDLLRTFVKL TGADQPGSQI EIKVNDITKS LAEISSLCQD LQVKILSVLV YPHDDPGVKV 190 200 210 LVFRVKTMNP LPFLQALQRN GHHVVWPSEQ RDLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of genes involved in utilization of acetate and acetoin in Bacillus subtilis." Grundy F.J., Waters D.A., Takova T.Y., Henkin T.M. Mol. Microbiol. 10:259-271(1993) [PubMed: 7934817] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region." Lapidus A., Galleron N., Sorokin A., Ehrlich S.-D. Microbiology 143:3431-3441(1997) [PubMed: 9387221] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L17309 Genomic DNA. Translation: AAA68285.1. AF008220 Genomic DNA. Translation: AAC00395.1. Z99119 Genomic DNA. Translation: CAB14948.1.
PIR	S39644.
RefSeq	NP_390848.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	937318.
GenomeReviews	Gene locus BSU29700 in contig AL009126_GR.
KEGG	bsu:BSU29700.
NMPDR	fig|224308.1.peg.2973.
Organism-specific databases
SubtiList	BG10368. acuB. [Micado]
CMR	Search...
Phylogenomic databases
HOGENOM	P39066.
Enzyme and pathway databases
BioCyc	BSUB224308:BSU2966-MON.
Family and domain databases
InterPro	IPR000644. Cysta_beta_synth_core. [Graphical view]
Pfam	PF00571. CBS. 1 hit. [Graphical view]
SMART	SM00116. CBS. 2 hits. [Graphical view]
PROSITE	PS51371. CBS. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACUB_BACSU

Accession

Primary (citable) accession number: P39066

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	November 25, 2008
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)