Reviewed, UniProtKB/Swiss-Prot P42827 (T2C1_COREQ)

Names and origin

Protein names

Recommended name:
    Type-2 restriction enzyme CeqI
      Short name=R.CeqI
    EC=3.1.21.4
Alternative name(s):
    Type II restriction enzyme CeqI
    Endonuclease CeqI

Gene names

Name:	ceqIR
Synonyms:	rceQI

Organism

Corynebacterium equii (Rhodococcus equi)

Taxonomic identifier

43767 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Function	Recognizes the double-stranded sequence GATATC and cleaves after T-3.
Catalytic activity	Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
Biological process	Restriction system
Molecular function	Endonuclease Hydrolase Nuclease
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 270	270	Type-2 restriction enzyme CeqI

Sequences

	Sequence		Length	Mass (Da)
	P42827-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 4D9EE9D689669394	FASTA	270	31,674
	10 20 30 40 50 60 MRTKNVCTFQ LILFPKVRSY IPLPLILKRI EITKNCISTR GETTKTSVTE KLSEEKTVVV 70 80 90 100 110 120 EPVFGFLKAH FHSTRFSEEA TKRRKRKWAL LVVILRKYTA RNSKQKRTKK TRQKGVRSSF 130 140 150 160 170 180 IDERTPFSFI FWLVLFRPLF NVLPCSAQSL FVQEFFITSP CLVCPAFPLE QNVSAFAPST 190 200 210 220 230 240 NGTKTKQMIT ITPMIRFIVV QLLTLRFSYR TVKGISPLRR RAWFFLWFNR SKCFCVGSIH 250 260 270 KRNKNKADKQ YQTEYSFHCC STPIIFILVR

References

[1]	"Cloning and characterization of the genes of the CeqI restriction-modification system." Izsvak Z., Jobbagy Z., Takacs I., Duda E. Int. J. Biochem. Cell Biol. 29:895-900(1997) [PubMed: 9304804] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z34099 Genomic DNA. Translation: CAA84005.1.
3D structure databases
ModBase	Search...
Family and domain databases
ProDom	P42827. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

T2C1_COREQ

Accession

Primary (citable) accession number: P42827

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	September 2, 2008
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)