Reviewed, UniProtKB/Swiss-Prot P43545 (SNZ3_YEAST)

Names and origin

Protein names

Recommended name:
    Probable pyridoxine biosynthesis protein SNZ3
Alternative name(s):
    PDX1 homolog 3

Gene names

Name:	SNZ3
Ordered Locus Names:	YFL059W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May be required for the production of pyridoxine (vitamin B6).
Induction	By the absence of external thiamine.
Sequence similarities	Belongs to the pdxS/SNZ family.

Ontologies

Keywords
Biological process	Pyridoxine biosynthesis
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyridoxine metabolic process Inferred from direct assay. Source: SGD thiamin biosynthetic process Ref.2 Inferred from mutant phenotype. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
SNO1	Q03144	1	EBI-17629,EBI-28190
SNO2	P53823	1	EBI-17629,EBI-28424
SNZ1	Q03148	1	EBI-17629,EBI-17618
SNZ2	P53824	1	EBI-17629,EBI-17623
SRP1	Q02821	1	EBI-17629,EBI-1797

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 298	298	Probable pyridoxine biosynthesis protein SNZ3

Sequences

	Sequence		Length	Mass (Da)
	P43545-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: FDBADC5546C460AC	FASTA	298	32,019
	10 20 30 40 50 60 MSEFKVKTGL AQMLKGGVIM DVVTPEQAII AERAGACAVM ALERIPADMR KSGQVCRMSD 70 80 90 100 110 120 PRMIKEIMEA VSIPVMAKVR IGHFVEAQIL EELQVDYIDE SEVLTPADWT HHIEKHNFKV 130 140 150 160 170 180 PFVCGAKDLG EALRRINEGA AMIRTKGEAG TGDVSEAVKH ITKIKAEIQQ YKENLKTESD 190 200 210 220 230 240 FAAKATELRV PVDLLKTTLS EGKLPVVNFA AGGVATPADA ALLMQLGCEG VFVGSGIFKS 250 260 270 280 290 SDPEKLACAI VEATTHYDNP AKLLQVSSDL GDLMGGISIQ SINEAGGKNG ARLSEIGW

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6." Rodriguez-Navarro S., Llorente B., Rodriguez-Manzaneque M.T., Ramne A., Uber G., Marchesan D., Dujon B., Herrero E., Sunnerhagen P., Perez-Ortin J.E. Yeast 19:1261-1276(2002) [PubMed: 12271461] [Abstract] Cited for: PROBABLE FUNCTION, INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D50617 Genomic DNA. Translation: BAA09182.1.
PIR	S56196.
RefSeq	NP_116596.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:1644N.
IntAct	P43545.
Genome annotation databases
Ensembl	YFL059W. Saccharomyces cerevisiae. [Contig view]
GeneID	850485.
GenomeReviews	Gene locus YFL059W in contig D50617_GR.
KEGG	sce:YFL059W.
Organism-specific databases
CYGD	YFL059w.
SGD	S000001835. SNZ3.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	P43545.
Gene expression databases
GermOnline	YFL059W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR001852. Snz1p/Sor1. [Graphical view]
Pfam	PF01680. SOR_SNZ. 1 hit. [Graphical view]
PIRSF	PIRSF029271. Pdx1. 1 hit.
ProDom	PD004958. Snz1p/Sor1. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00343. Snz1p/Sor1. 1 hit.
PROSITE	PS01235. PDXS_SNZ_1. 1 hit. PS51129. PDXS_SNZ_2. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
LinkHub	P43545.
ProtoNet	Search...

Entry information

Entry name

SNZ3_YEAST

Accession

Primary (citable) accession number: P43545

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	July 22, 2008
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)