Reviewed, UniProtKB/Swiss-Prot P44487 (UXUR_HAEIN)

Names and origin

Protein names

Recommended name:
    Uxu operon regulator

Gene names

Name:	uxuR
Ordered Locus Names:	HI0054

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Repressor for the uxuRBA operon By similarity.
Sequence similarities	Contains 1 HTH gntR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Molecular function	Repressor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 266	266	Uxu operon regulator		PRO_0000050671
Regions
	Domain	23 – 91	69	HTH gntR-type
	DNA binding	51 – 70	20	H-T-H motif Potential

Sequences

	Sequence		Length	Mass (Da)
	P44487-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: B54E86EBA120CDC0	FASTA	266	30,919
	10 20 30 40 50 60 MSHITKIKNW NTNLRKNMEN IVNRTYTRIG QLLKQDISQG IYSIGDKLPT EREISEKFGV 70 80 90 100 110 120 SRTIVREAMV MLEVEKLVEV KKGSGVYVVR TPESIHMEHS DLPDVGPFEL LQARQLLESS 130 140 150 160 170 180 IAEFAALQAT KKDILNLKQI LNREKELLTQ NQDDYSADKD FHLALAEITQ NDVLVKLQEQ 190 200 210 220 230 240 LWQYRFNSAM WAQLHSRILQ NDYHHLWIED HQTILSAIQK KNANEARKAM WQHLENVKVK 250 260 LFELSDVEDP HFDGYLFNTN PVVVGI

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21732.1.
PIR	D64045.
RefSeq	NP_438227.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950951.
GenomeReviews	Gene locus HI0054 in contig L42023_GR.
KEGG	hin:HI0054.
NMPDR	fig|71421.1.peg.53.
TIGR	HI0054.
Phylogenomic databases
HOGENOM	P44487.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0054-MON.
Family and domain databases
InterPro	IPR011711. GntR_C. IPR000524. HTH_GntR. IPR011991. Wing_hlx_DNA_bd. [Graphical view]
Gene3D	G3DSA:1.10.10.10. Wing_hlx_DNA_bd. 1 hit.
Pfam	PF07729. FCD. 1 hit. PF00392. GntR. 1 hit. [Graphical view]
PRINTS	PR00035. HTHGNTR.
SMART	SM00345. HTH_GNTR. 1 hit. [Graphical view]
PROSITE	PS50949. HTH_GNTR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UXUR_HAEIN

Accession

Primary (citable) accession number: P44487

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)