SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P52076

- QSEB_ECOLI

UniProt

P52076 - QSEB_ECOLI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Transcriptional regulatory protein QseB
Gene
qseB, ygiX, b3025, JW2993
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. Currently it is not known whether this effect is direct or not.1 Publication

GO - Molecular functioni

  1. core promoter sequence-specific DNA bindingInferred from direct assayi PubMed 16194231 Source: EcoCyc
  2. phosphorelay response regulator activityInferred from mutant phenotypei PubMed 11929534 Source: EcoCyc
Complete GO annotation...

GO - Biological processi

  1. intracellular signal transductionInferred from mutant phenotypei PubMed 11929534 Source: GOC
  2. positive regulation of gene expressionInferred from direct assayi PubMed 11929534 Source: EcoCyc
  3. quorum sensingInferred from mutant phenotypei PubMed 11929534 Source: EcoCyc
  4. regulation of transcription, DNA-templatedInferred from electronic annotationi Source: UniProtKB-KW
  5. response to metal ionInferred from mutant phenotypei PubMed 12897016 Source: EcoCyc
  6. transcription, DNA-templatedInferred from experimenti PubMed 11929534 Source: EcoCyc
  1. phosphorelay response regulator activityInferred from mutant phenotypei PubMed 11929534 Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7575-MONOMER.
ECOL316407:JW2993-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein QseB
Gene namesi
Name:qseB
Synonyms:ygiX
Ordered Locus Names:b3025, JW2993
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG13026. qseB.

Subcellular locationi

Cytoplasm Reviewed prediction

GO - Cellular componenti

  1. cytoplasmInferred from electronic annotationi Source: UniProtKB-SubCell
  2. protein-DNA complexInferred from direct assayi PubMed 16194231 Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Transcriptional regulatory protein QseB
PRO_0000081025Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei51 – 5114-aspartylphosphate By similarity

Post-translational modificationi

Phosphorylated by QseC Inferred.

Keywords - PTMi

Phosphoprotein

Expressioni

Inductioni

By the signal autoinducer AI-2, through MqsR.1 Publication

Gene expression databases

GenevestigatoriP52076.

Interactioni

Protein-protein interaction databases

IntActiP52076. 5 interactions.
STRINGi511145.b3025.

Structurei

3D structure databases

ProteinModelPortaliP52076.
SMRiP52076. Positions 1-216.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 116116Response regulatory
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0745.
HOGENOMiHOG000034815.
KOiK07666.
OMAiGTEVCRE.
OrthoDBiEOG6G4VQG.
PhylomeDBiP52076.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P52076-1 [UniParc]FASTA

« Hide

MRILLIEDDM LIGDGIKTGL SKMGFSVDWF TQGRQGKEAL YSAPYDAVIL    50
DLTLPGMDGR DILREWREKG QREPVLILTA RDALAERVEG LRLGADDYLC 100
KPFALIEVAA RLEALMRRTN GQASNELRHG NVMLDPGKRI ATLAGEPLTL 150
KPKEFALLEL LMRNAGRVLS RKLIEEKLYT WDEEVTSNAV EVHVHHLRRK 200
LGSDFIRTVH GIGYTLGEK 219
Length:219
Mass (Da):24,678
Last modified:October 1, 1996 - v1
Checksum:i9408B2B7261E042E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U28377 Genomic DNA. Translation: AAA69193.1.
U00096 Genomic DNA. Translation: AAC76061.1.
AP009048 Genomic DNA. Translation: BAE77081.1.
PIRiG65089.
RefSeqiNP_417497.1. NC_000913.3.
YP_491217.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC76061; AAC76061; b3025.
BAE77081; BAE77081; BAE77081.
GeneIDi12933397.
945369.
KEGGiecj:Y75_p2951.
eco:b3025.
PATRICi32121462. VBIEscCol129921_3118.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U28377 Genomic DNA. Translation: AAA69193.1 .
U00096 Genomic DNA. Translation: AAC76061.1 .
AP009048 Genomic DNA. Translation: BAE77081.1 .
PIRi G65089.
RefSeqi NP_417497.1. NC_000913.3.
YP_491217.1. NC_007779.1.

3D structure databases

ProteinModelPortali P52076.
SMRi P52076. Positions 1-216.
ModBasei Search...

Protein-protein interaction databases

IntActi P52076. 5 interactions.
STRINGi 511145.b3025.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC76061 ; AAC76061 ; b3025 .
BAE77081 ; BAE77081 ; BAE77081 .
GeneIDi 12933397.
945369.
KEGGi ecj:Y75_p2951.
eco:b3025.
PATRICi 32121462. VBIEscCol129921_3118.

Organism-specific databases

EchoBASEi EB2844.
EcoGenei EG13026. qseB.

Phylogenomic databases

eggNOGi COG0745.
HOGENOMi HOG000034815.
KOi K07666.
OMAi GTEVCRE.
OrthoDBi EOG6G4VQG.
PhylomeDBi P52076.

Enzyme and pathway databases

BioCyci EcoCyc:G7575-MONOMER.
ECOL316407:JW2993-MONOMER.

Miscellaneous databases

PROi P52076.

Gene expression databases

Genevestigatori P52076.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view ]
SMARTi SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52172. SSF52172. 1 hit.
PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete genome sequence of Escherichia coli K-12."
    Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
    Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli."
    Sperandio V., Torres A.G., Kaper J.B.
    Mol. Microbiol. 43:809-821(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Strain: K12 and O157:H7.
  4. "Autoinducer 2 controls biofilm formation in Escherichia coli through a novel motility quorum-sensing regulator (MqsR, B3022)."
    Gonzalez Barrios A.F., Zuo R., Hashimoto Y., Yang L., Bentley W.E., Wood T.K.
    J. Bacteriol. 188:305-316(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION BY AI-2 AND MQSR.
    Strain: K12 / ATCC 25404 / DSM 5698 / NCIMB 11290, K12 / DH5-alpha and K12 / W3110 / ATCC 27325 / DSM 5911.

Entry nameiQSEB_ECOLI
AccessioniPrimary (citable) accession number: P52076
Secondary accession number(s): Q2M9H5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 14, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

External Data

Dasty 3

Similar proteinsi