Reviewed, UniProtKB/Swiss-Prot P56117 (Y190_HELPY)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein HP_0190

Gene names

Ordered Locus Names:

HP_0190

Organism

Helicobacter pylori (Campylobacter pylori) [Complete proteome] [HAMAP]

Taxonomic identifier

210 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell membrane; Single-pass membrane proteinPotential.
Sequence similarities	Belongs to the phospholipase D family. Cardiolipin synthase subfamily. Contains 2 PLD phosphodiesterase domains.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Repeat Transmembrane
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 502	502	Uncharacterized protein HP_0190
Regions
	Transmembrane	1 – 21	21	Potential
	Domain	162 – 189	28	PLD phosphodiesterase 1
	Domain	396 – 423	28	PLD phosphodiesterase 2

Sequences

	Sequence		Length	Mass (Da)
	P56117-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: C80911F2FB59C714	FASTA	502	58,287
	10 20 30 40 50 60 MKIFLVFLSV FFFNGCFGLV YKTPISSSPI SYDPYTTPIG SLYAEKLKEN PNHSAAILLE 70 80 90 100 110 120 DGFDALLHRV GLIRMSQKSI DMQTYIYKND LSSQVIAKEL LNAANRGVKV RILLDDNGLD 130 140 150 160 170 180 SDFSDIMLLN FHKNIEVKIF NPYYIRNKGL RYFEMLADYE RIKKRMHNKL FIVDNFAVII 190 200 210 220 230 240 GGRNIGDNYF DNDLDTNFLD LDALFFGGVA SKAKESFERY WRFHRSIPVS LLRTHKRLKN 250 260 270 280 290 300 NAKEIAKLHE KIPISAEDKN QFEKKVNDFI DRFQKYQYPI YYGNAIFLAD SPKKIDTPLY 310 320 330 340 350 360 SPIKIAFEKA LKNAKDSVFI ASSYFIPGKK MMKIFKNQIS KGIELNILTN SLSSTDAIVV 370 380 390 400 410 420 YGAWERYRNQ LVRMGANVYE IRNDFFNRQI KGRFSTKHSL HGKTIVFDDN LTLLGSFNID 430 440 450 460 470 480 PRSAYINTES AVLFDNPSFA KRVRLSLKDH AQQSWHLVVY RHRVIWEAVE EGILIHEKTS 490 500 PDTSFFLRLI KEWSKVLPER EL

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000511 Genomic DNA. Translation: AAD07257.1.
PIR	F64543.
RefSeq	NP_206989.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	899993.
GenomeReviews	Gene locus HP_0190 in contig AE000511_GR.
KEGG	hpy:HP0190.
NMPDR	fig|85962.1.peg.187.
TIGR	HP_0190.
Phylogenomic databases
HOGENOM	P56117.
Family and domain databases
InterPro	IPR001736. PLD. [Graphical view]
Pfam	PF00614. PLDc. 2 hits. [Graphical view]
SMART	SM00155. PLDc. 2 hits. [Graphical view]
PROSITE	PS50035. PLD. 2 hits. [Graphical view]
ProDom	P56117. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

Y190_HELPY

Accession

Primary (citable) accession number: P56117

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	September 2, 2008
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)