Reviewed, UniProtKB/Swiss-Prot P56628 (RL22B_YEAST)

Names and origin

Protein names

Recommended name:
    60S ribosomal protein L22-B
Alternative name(s):
    L1c
    YL31
    RP4

Gene names

Name:	RPL22B
Ordered Locus Names:	YFL034C-A
ORF Names:	YFL034BC

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	122 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).
Subcellular location	Cytoplasm.
Miscellaneous	Present with 74700 molecules/cell in log phase SD medium. There are 2 genes for L22 in yeast.
Sequence similarities	Belongs to the ribosomal protein L22e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from direct assay. Source: SGD
Cellular component	cytosolic large ribosomal subunit Inferred from direct assay. Source: SGD
Molecular function	structural constituent of ribosome Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 122	121	60S ribosomal protein L22-B

Sequences

	Sequence		Length	Mass (Da)
	P56628-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 2A21CEBC75C20A6B	FASTA	122	13,827
	10 20 30 40 50 60 MAPNTSRKQK VIKTLTVDVS SPTENGVFDP ASYSKYLIDH IKVDGAVGNL GNAIEVTEDG 70 80 90 100 110 120 SIVTVVSSAK FSGKYLKYLT KKYLKKNQLR DWIRFVSIRQ NQYKLVFYQV TPEDADEEED DE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed: 9559554] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D50617 Genomic DNA. No translation available.
PIR	S58649.
RefSeq	NP_116619.1.
3D structure databases
ModBase	Search...
Proteomic databases
PeptideAtlas	P56628.
Genome annotation databases
Ensembl	YFL034C-A. Saccharomyces cerevisiae. [Contig view]
GeneID	850509.
GenomeReviews	Gene locus YFL034C-A in contig D50617_GR.
KEGG	sce:YFL034C-A.
NMPDR	fig|4932.3.peg.2244.
Organism-specific databases
CYGD	YFL034c-a.
SGD	S000006436. RPL22B.
Phylogenomic databases
HOGENOM	P56628.
Gene expression databases
ArrayExpress	P56628.
GermOnline	YFL034C-A. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR002671. Ribosomal_L22e. [Graphical view]
PANTHER	PTHR10064. Ribosomal_L22e. 1 hit.
Pfam	PF01776. Ribosomal_L22e. 1 hit. [Graphical view]
ProDom	PD007306. Ribosomal_L22e. 1 hit. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
LinkHub	P56628.
ProtoNet	Search...

Entry information

Entry name

RL22B_YEAST

Accession

Primary (citable) accession number: P56628

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	January 23, 2007
Last modified:	July 22, 2008
This is version 50 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)