Reviewed, UniProtKB/Swiss-Prot P57118 (ATP6_BUCAI)

Names and origin

Protein names

Recommended name:
    ATP synthase a chain
    EC=3.6.3.14
Alternative name(s):
    ATPase protein 6

Gene names

Name:	atpB
Ordered Locus Names:	BU002

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane By similarity.
Catalytic activity	ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
Subunit structure	F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c By similarity.
Subcellular location	Cell membrane; Multi-pass membrane proteinPotential.
Sequence similarities	Belongs to the ATPase A chain family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 274	274	ATP synthase a chain
Regions
	Transmembrane	44 – 64	21	Potential
	Transmembrane	110 – 130	21	Potential
	Transmembrane	156 – 176	21	Potential
	Transmembrane	179 – 199	21	Potential
	Transmembrane	212 – 232	21	Potential
	Transmembrane	243 – 263	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P57118-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 4B2321336EFE78A4	FASTA	274	31,364
	10 20 30 40 50 60 MILEKISDPQ KYISHHLSHL QIDLRSFKII QPGALSSDYW TVNVDSMFFS LVLGSFFLSI 70 80 90 100 110 120 FYMVGKKITQ GIPGKLQTAI ELIFEFVNLN VKSMYQGKNA LIAPLSLTVF IWVFLMNLMD 130 140 150 160 170 180 LVPIDFFPFI SEKVFELPAM RIVPSADINI TLSMSLGVFF LILFYTVKIK GYVGFLKELI 190 200 210 220 230 240 LQPFNHPVFS IFNFILEFVS LVSKPISLGL RLFGNMYAGE MIFILIAGLL PWWTQCFLNV 250 260 270 PWAIFHILII SLQAFIFMVL TIVYLSMASQ SHKD

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB12730.1.
RefSeq	NP_239844.1.
3D structure databases
HSSP	HSSP built from PDB template 1C17 based on UniProtKB P00855.
SMR	P57118. Positions 96-266.
ModBase	Search...
Genome annotation databases
GeneID	1109511.
GenomeReviews	Gene locus BU002 in contig BA000003_GR.
KEGG	buc:BU002.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P57118.
Enzyme and pathway databases
BioCyc	BSP107806:BU002-MON.
Family and domain databases
InterPro	IPR000568. ATPase_F0_A. [Graphical view]
Gene3D	G3DSA:1.20.120.220. ATPase_F0_A. 1 hit.
PANTHER	PTHR11410. ATPase_F0_A. 1 hit.
Pfam	PF00119. ATP-synt_A. 1 hit. [Graphical view]
PRINTS	PR00123. ATPASEA.
TIGRFAMs	TIGR01131. ATP_synt_6_or_A. 1 hit.
PROSITE	PS00449. ATPASE_A. 1 hit. [Graphical view]
ProDom	P57118. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ATP6_BUCAI

Accession

Primary (citable) accession number: P57118

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	September 2, 2008
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)