Reviewed, UniProtKB/Swiss-Prot P57133 (EFP_BUCAI)

Names and origin

Protein names

Recommended name:
    Elongation factor P
      Short name=EF-P

Gene names

Name:	efp
Ordered Locus Names:	BU020

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase By similarity.
Pathway	Protein biosynthesis; polypeptide chain elongation.
Sequence similarities	Belongs to the elongation factor P family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 189	189	Elongation factor P

Sequences

	Sequence		Length	Mass (Da)
	P57133-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: B676EBE1497595A1	FASTA	189	21,721
	10 20 30 40 50 60 MRIYHSNNFR SGRKIIFENE PCLIESSEFV KPGKGQSFVR VKLRKLLTKQ LIEKTFKSTD 70 80 90 100 110 120 SLEIADIIEY TLSYLYNDGR FWYFINNNTF EELSVDEKII GVHKKWLLEQ DTCIVTLWNN 130 140 150 160 170 180 QPISITPNNF VNLKVIHVQA TLKGDTINTS STKLATLSTG AIVRVPLFIQ VGSLIKVDTR SGEYVSRIK

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB12747.1. Different initiation.
RefSeq	NP_239861.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1109528.
GenomeReviews	Gene locus BU020 in contig BA000003_GR.
KEGG	buc:BU020.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P57133.
Enzyme and pathway databases
BioCyc	BSP107806:BU020-MON.
Family and domain databases
HAMAP	MF_00141. [Tree]
InterPro	IPR015365. Elong-fact-P_C. IPR012340. NA-bd_OB-fold. IPR011768. Transl_elong_EFP. IPR013185. Transl_elong_KOW-like. IPR001059. Transl_elong_P/YeiP_cen. IPR013852. Transl_elong_P/YeiP_CS. IPR014722. Transl_SH3_like_sub. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 2 hits. G3DSA:2.30.30.30. Ribosomal_L2. 1 hit.
Pfam	PF01132. EFP. 1 hit. PF08207. EFP_N. 1 hit. PF09285. Elong-fact-P_C. 1 hit. [Graphical view]
PIRSF	PIRSF005901. EF-P. 1 hit.
TIGRFAMs	TIGR00038. efp. 1 hit.
PROSITE	PS01275. EFP. 1 hit. [Graphical view]
ProDom	P57133. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

EFP_BUCAI

Accession

Primary (citable) accession number: P57133

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	July 22, 2008
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)