Reviewed, UniProtKB/Swiss-Prot P57149 (RL1_BUCAI)

Names and origin

Protein names

Recommended name:
    50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	BU037

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity.
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 231	231	50S ribosomal protein L1

Sequences

	Sequence		Length	Mass (Da)
	P57149-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 82E657C4B28DC27E	FASTA	231	25,485
	10 20 30 40 50 60 MNKKTKRMKK IKEHINFAKL HHIDETIDLL KKSSTVKFNE SIDIAINLGI NSKKSDQNIR 70 80 90 100 110 120 SSTVLPNGIG RSIRVAVFTQ GDNIAIAKDA GAELIGMEDL SEKIKKEGVD FDVVIATPDA 130 140 150 160 170 180 MKIVTQLGQI LGPRNLMPNT KLGTITTNIA EAIKNAKTGQ VRYRNDKNGI IHATIGRINF 190 200 210 220 230 HKNEIKENLN VFLESIKKAK PPQSKGIYIK KIVLSTTMGV GLMVDQSTLS L

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB12764.1.
RefSeq	NP_239878.1.
3D structure databases
HSSP	HSSP built from PDB template 1AD2 based on UniProtKB P27150.
ModBase	Search...
Genome annotation databases
GeneID	1109545.
GenomeReviews	Gene locus BU037 in contig BA000003_GR.
KEGG	buc:BU037.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P57149.
Enzyme and pathway databases
BioCyc	BSP107806:BU037-MON.
Family and domain databases
HAMAP	MF_01318. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 1 hit.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
ProDom	PD001314. Ribosomal_L1. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01169. rplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

RL1_BUCAI

Accession

Primary (citable) accession number: P57149

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	July 22, 2008
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)