Reviewed, UniProtKB/Swiss-Prot P85321 (PA50C_BISBO)

Names and origin

Protein names	Recommended name:     Pregnancy-associated glycoprotein 50C     EC=3.4.23.- Alternative name(s):     EbPAG-C 50 kDa
Organism	Bison bonasus (European bison)
Taxonomic identifier	9902 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bison

Protein attributes

Sequence length	12 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Secreted › extracellular space.
Tissue specificity	Chorionic epithelium (trophectoderm) and placental cotyledons.
Developmental stage	Expressed at 45 dpc.
Miscellaneous	On the 2D-gel the determined pI of this protein is: 5.7, its MW is: 50 kDa.
Sequence similarities	Belongs to the peptidase A1 family.

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Aspartyl protease Hydrolase Protease
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – ›12	›12	Pregnancy-associated glycoprotein 50C
Amino acid modifications
	Glycosylation	9	1	N-linked (GlcNAc...)
Experimental info
	Non-terminal residue	12	1

Sequences

	Sequence		Length	Mass (Da)
	P85321-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 4AC4CE378AB86407	FASTA	12	1,288
	10 SQISLRGSNL TI

References

[1]

"Identification of multiple pregnancy-associated glycoproteins (PAGs) purified from the European bison (Eb; Bison bonasus L.) placentas." Kiewisz J., Sousa N.M., Beckers J.F., Panasiewicz G., Gizejewski Z., Szafranska B. Anim. Reprod. Sci. 0:0-0(2008) [PubMed: 18538513] [Abstract] Cited for: PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, GLYCOSYLATION AT ASN-9. Tissue: Placenta.

Cross-references

3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR001969. Pept_Asp_AS. [Graphical view]
PROSITE	PS00141. ASP_PROTEASE. Partial match. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

PA50C_BISBO

Accession

Primary (citable) accession number: P85321

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	July 22, 2008
This is version 2 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)