Reviewed, UniProtKB/Swiss-Prot P94526 (ARAL_BACSU)

Names and origin

Protein names

Recommended name:
    Arabinose operon protein araL

Gene names

Name:	araL
Synonyms:	yseA
Ordered Locus Names:	BSU28770

Organism

Bacillus subtilis [Complete proteome] [HAMAP]

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Induction

Transcription is repressed by glucose and by the binding of araR to the operon promoter. L-arabinose acts as an inducer by inhibiting the binding of araR to the DNA, thus allowing expression of the gene.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Arabinose operon protein araL		PRO_0000064658

Sequences

	Sequence		Length	Mass (Da)
	P94526-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: E035F890C004C51A	FASTA	272	29,315
	10 20 30 40 50 60 MRIMASHDTP VSPAGILIDL DGTVFRGNEL IEGAREAIKT LRRMGKKIVF LSNRGNISRA 70 80 90 100 110 120 MCRKKLLGAG IETDVNDIVL SSSVTAAFLK KHYRFSKVWV LGEQGLVDEL RLAGVQNASE 130 140 150 160 170 180 PKEADWLVIS LHETLTYDDL NQAFQAAAGG ARIIATNKDR SFPNEDGNAI DVAGMIGAIE 190 200 210 220 230 240 TSAQAKTELV VGKPSWLMAE AACTAMGLSA HECMIIGDSI ESDIAMGKLY GMKSALVLTG 250 260 270 SAKQGEQRLY TPDYVLDSIK DVTKLAEEGI LI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression." Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H. Microbiology 143:957-969(1997) [PubMed: 9084180] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism." Wipat A., Carter N., Brignell C.S., Guy J.B., Piper K., Sanders J., Emmerson P.T., Harwood C.R. Microbiology 142:3067-3078(1996) [PubMed: 8969504] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[3]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[4]	"Mode of action of AraR, the key regulator of L-arabinose metabolism in Bacillus subtilis." Mota L.J., Tavares P., Sa-Nogueira I.M.G. Mol. Microbiol. 33:476-489(1999) [PubMed: 10417639] [Abstract] Cited for: TRANSCRIPTIONAL REGULATION.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X89408 Genomic DNA. Translation: CAA61588.1. Different initiation. X89810 Genomic DNA. Translation: CAA61932.1. Z75208 Genomic DNA. Translation: CAA99590.1. Z99118 Genomic DNA. Translation: CAB14837.1.
PIR	G69587.
RefSeq	NP_390755.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	937431.
GenomeReviews	Gene locus BSU28770 in contig AL009126_GR.
KEGG	bsu:BSU28770.
NMPDR	fig|224308.1.peg.2880.
Organism-specific databases
SubtiList	BG11908. araL. [Micado]
CMR	Search...
Phylogenomic databases
HOGENOM	P94526.
Enzyme and pathway databases
BioCyc	BSUB224308:BSU2873-MON.
Family and domain databases
InterPro	IPR005834. Dehalogen-like_hydro. IPR006357. HAD-SF_hydro_IIA. [Graphical view]
Pfam	PF00702. Hydrolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01460. HAD-SF-IIA. 1 hit.
BLOCKS	Search...
ProtoNet	Search...
Other Resources
LinkHub	P94526.

Entry information

Entry name

ARAL_BACSU

Accession

Primary (citable) accession number: P94526

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2002
Last sequence update:	May 1, 1997
Last modified:	November 4, 2008
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)