Reviewed, UniProtKB/Swiss-Prot Q03735 (YML7_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized RNA-binding protein YML117W

Gene names

Ordered Locus Names:	YML117W
ORF Names:	YM8339.02

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	1134 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous	Present with 1540 molecules/cell in log phase SD medium.
Sequence similarities	Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Keywords
Ligand	RNA-binding
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 1134	1134	Uncharacterized RNA-binding protein YML117W
Regions
	Domain	653 – 726	74	RRM
Amino acid modifications
	Modified residue	445	1	Phosphoserine
	Modified residue	448	1	Phosphoserine
	Modified residue	449	1	Phosphoserine
	Modified residue	464	1	Phosphoserine
	Modified residue	467	1	Phosphoserine
	Modified residue	497	1	Phosphoserine
	Modified residue	614	1	Phosphoserine
	Modified residue	993	1	Phosphoserine
	Modified residue	1018	1	Phosphoserine
	Modified residue	1125	1	Phosphoserine

Sequences

	Sequence		Length	Mass (Da)
	Q03735-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 47B0FF7C5B98A053	FASTA	1,134	126,139
	10 20 30 40 50 60 MSNSNSKKPV ANYAYRQQQD YNGMNAMVGN PMMYHPVDFV NGAGQYGPSQ HPAYYTNSPL 70 80 90 100 110 120 PNIPPTPFDT AYGASLFPSH LLMGSPFVSS PNMQSGYNSA RSSNLKRKAY SRPVSNHNGY 130 140 150 160 170 180 NGNSNSNQNN TNNGMVTPSN YYRMGRNSFS RNNNSTRNVT HNNNKGCDTR NNSGRRTFAR 190 200 210 220 230 240 NNIFDDILPE MLLQRPFCIN YKVLPTGDDA YRTRSLLIEN VDHSIDLHSI VKNFVKSNTL 250 260 270 280 290 300 ESAYLIEGGK SDDSKDVETK NLSILISFLT KGDCLNFYNN ILQRLSEFKT FLKSEALNLK 310 320 330 340 350 360 FVCLNYDPKC LPTFIESEAL TENAEEADIT NGSTMISASL HHNIANKDAT RSIIIEFKSP 370 380 390 400 410 420 VEKSDLFKKK LQFLDRSKNK RYILESIDLV NTDVPSNQFP ENYAVLTFLN ISMAIEVLDY 430 440 450 460 470 480 LKKYSKNLGI SKCFYVSLAP LVVSSARSSV ANIYEGKTST HRLSVPSVTA GNNNDSNNNG 490 500 510 520 530 540 NNNKSNMSGI TTLNNNSSIG VSVYGHSNMS LTSLSSSVSL NEEIDMLATK LQGVELDGTY 550 560 570 580 590 600 LEINYRDYQT PTIEEHSTHL SNVKISKTTE NSRQFSQDIP SPLPLNEHMF MNDSNQSNGA 610 620 630 640 650 660 IIPQQLIATP SPVSPNLQMN QRVLPNPITQ SLEQNFNVSA KVASSMGSDI GNRTIYIGNI 670 680 690 700 710 720 NPRSKAEDIC NVVRGGILQS IKYIPEKKIC FVTFIEAPSA VQFYANSFID PIVLHGNMLR 730 740 750 760 770 780 VGWGHYSGPL PKLISLAVTI GASRNVYVSL PEFAFKEKFI HDPQYKKLHE TLSLPDAEQL 790 800 810 820 830 840 REDFSTYGDI EQINYLSDSH CCWINFMNIS SAISLVEEMN KESTVQNESG EVTLKRATEE 850 860 870 880 890 900 KFGGRYKGLL INYGKDRCGN INKNLIAGKN SRFYKKVKRP SYNIRLSKLE EKRRQNEIDE 910 920 930 940 950 960 KEKAFDKPLN LESLGISLDA HKDNGGGETG TANNTGHENE SELEAENENG NETGSFGGLG 970 980 990 1000 1010 1020 LAVASSDVKR ATSDETDYED IFNKSSGSSD SSSDVEVIMH SPSDPEYALK SQTLRSSSQT 1030 1040 1050 1060 1070 1080 VINSKRPVKI EDEEEAVGMS QLNYRSSLRQ APPRAPSTLS YNHSKNNETP MQDIFTNGET 1090 1100 1110 1120 1130 ANNRKKKRGS FARHRTIPGS DVMAQYLAQV QHSTFMYAAN ILGASAEDNT HPDE

References

[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[3]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-464 AND SER-993, MASS SPECTROMETRY.
[4]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-445; SER-448; SER-449; SER-467; SER-497; SER-614; SER-993; SER-1018 AND SER-1125, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z49210 Genomic DNA. Translation: CAA89101.1.
PIR	S53955.
RefSeq	NP_013589.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:2976N.
IntAct	Q03735.
Genome annotation databases
Ensembl	YML117W. Saccharomyces cerevisiae. [Contig view]
GeneID	854922.
GenomeReviews	Gene locus YML117W in contig Z71257_GR.
KEGG	sce:YML117W.
NMPDR	fig|4932.3.peg.4625.
Organism-specific databases
CYGD	YML117w.
SGD	S000004585. NAB6.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	Q03735.
Gene expression databases
ArrayExpress	Q03735.
GermOnline	YML117W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000504. RRM_RNP1. [Graphical view]
SMART	SM00360. RRM. 1 hit. [Graphical view]
PROSITE	PS50102. RRM. 1 hit. [Graphical view]
ProDom	Q03735. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
LinkHub	Q03735.
ProtoNet	Search...

Entry information

Entry name

YML7_YEAST

Accession

Primary (citable) accession number: Q03735

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	September 2, 2008
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)