Reviewed, UniProtKB/Swiss-Prot Q07232 (ATPB_BUCAP)

Names and origin

Protein names

Recommended name:
    ATP synthase subunit beta
      Short name=ATPase subunit beta
    EC=3.6.3.14
Alternative name(s):
    ATP synthase F1 sector subunit beta

Gene names

Name:	atpD
Synonyms:	uncD
Ordered Locus Names:	BUsg_008

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	466 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity.
Catalytic activity	ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
Subunit structure	F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.
Subcellular location	Cell membrane; Peripheral membrane proteinBy similarity.
Sequence similarities	Belongs to the ATPase alpha/beta chains family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	plasma membrane ATP synthesis coupled proton transport Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 466	466	ATP synthase subunit beta
Regions
	Nucleotide binding	156 – 163	8	ATP By similarity
Experimental info
	Sequence conflict	280	1	E → G Ref.4 Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Q07232-1 [UniParc]. Last modified December 15, 1998. Version 2. Checksum: F0A1570A2DA470D9	FASTA	466	51,349
	10 20 30 40 50 60 MIATGKIIQI IGAVVDVEFD QNSVPKIYNA LEVKNKKIQL ILEVQQQLGA GIVRTIAMGS 70 80 90 100 110 120 TNGLKRGLIV IDLGHYIKVP VGQATLGRII NVLGKTIDNK GPLKNLDNSK LEYWEIHRSA 130 140 150 160 170 180 PSYQEQASSQ EILETGIKVI DLICPFSKGG KVGLFGGAGV GKTVNMMELI RNIAIEHSGY 190 200 210 220 230 240 SVFTGVGERT REGNDFYHEM KDSKVLDKVS LVYGQMNEPP GNRLRVAFTG LTIAEKFRDE 250 260 270 280 290 300 GRDVLLFIDN IYRYTLAGTE VSALLGRMPS AVGYQPTLAE EMGLLQERIT STKEGSITSV 310 320 330 340 350 360 QAVYVPADDL TDPSPATTFA HLDSTVTLSR QIAALGIYPA IDPLNSTSRQ LDPYIVGDEH 370 380 390 400 410 420 YDTARGVQSI LQRYQELKDI IAILGMDELS QEDKILVSRA RKIQRFLSQP FFVAEVFTGF 430 440 450 460 PGKYVSLKDN IRAFKGIIGG EFDNLPEQAF YMVGTIEEVI KKAKLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The (F1F0) ATP synthase of Buchnera aphidicola (endosymbiont of aphids): genetic analysis of the putative ATP operon." Clark M.A., Baumann P. Curr. Microbiol. 35:84-89(1997) [PubMed: 9216881] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of a 34.7-kb DNA segment from the genome of Buchnera aphidicola (endosymbiont of aphids) containing groEL, dnaA, the atp operon, gidA, and rho." Clark M.A., Baumann L., Baumann P. Curr. Microbiol. 36:158-163(1998) [PubMed: 9516544] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"Aspects of energy-yielding metabolism in the aphid, Schizaphis graminum, and its endosymbiont: detection of gene fragments potentially coding for the ATP synthase beta-subunit and glyceraldehyde-3-phosphate dehydrogenase." Clark M.A., Baumann P. Curr. Microbiol. 26:233-237(1993) [PubMed: 7763501] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 164-314.
[5]	"Effect of selection and random drift in the evolution of aphids endosymbionts." Latorre A., Buades C., Sabater B., Moya A. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 164-314.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF008210 Genomic DNA. Translation: AAC38110.1. AE013218 Genomic DNA. Translation: AAM67580.1. Z15147 Genomic DNA. Translation: CAA78853.1. AJ247128 Genomic DNA. Translation: CAB95753.1.
PIR	S37647.
RefSeq	NP_660369.1.
3D structure databases
HSSP	HSSP built from PDB template 1H8E based on UniProtKB P00829.
ModBase	Search...
Genome annotation databases
GeneID	1005596.
GenomeReviews	Gene locus BUsg_008 in contig AE013218_GR.
KEGG	bas:BUsg008.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q07232.
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG008-MON.
Family and domain databases
HAMAP	MF_01347. [Tree]
InterPro	IPR003593. AAA+_ATPase_core. IPR000793. ATPase_a_b_C. IPR004100. ATPase_a_b_N. IPR000194. ATPase_a_b_nl_bd. IPR005722. ATPase_F1_b. [Graphical view]
PANTHER	PTHR15184:SF8. ATPase_F1_b. 1 hit.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01039. atpD. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. [Graphical view]
ProDom	Q07232. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

ATPB_BUCAP

Accession

Primary (citable) accession number: Q07232
Secondary accession number(s): O51872, Q93V14

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	December 15, 1998
Last modified:	September 2, 2008
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)