Reviewed, UniProtKB/Swiss-Prot Q09681 (GMH2_SCHPO)

Names and origin

Protein names

Recommended name:
    Probable alpha-1,2-galactosyltransferase gmh2
    EC=2.4.1.-

Gene names

Name:	gmh2
ORF Names:	SPAC5H10.13c

Organism

Schizosaccharomyces pombe (Fission yeast) [Complete proteome]

Taxonomic identifier

4896 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Golgi apparatus membrane; Single-pass type II membrane proteinPotential.
Sequence similarities	Belongs to the glycosyltransferase 34 family.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fungal-type cell wall biogenesis Traceable author statement. Source: GeneDB_SPombe protein amino acid galactosylation Traceable author statement. Source: GeneDB_SPombe
Cellular component	Golgi membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	transferase activity, transferring hexosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	Probable alpha-1,2-galactosyltransferase gmh2		PRO_0000215167
Regions
	Topological domain	1 – 11	11	Cytoplasmic Potential
	Transmembrane	12 – 32	21	Signal-anchor for type II membrane protein Potential
	Topological domain	33 – 346	314	Lumenal Potential
Amino acid modifications
	Glycosylation	64	1	N-linked (GlcNAc...) Potential
	Glycosylation	142	1	N-linked (GlcNAc...) Potential
	Glycosylation	224	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q09681-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 1AD26CCDFABC0D3E	FASTA	346	39,108
	10 20 30 40 50 60 MALMLSRIPR RFFFLFLTVG LIAGAFLYSL IYFVDVDLVS KVNQLYDQQI APMLSDAIGT 70 80 90 100 110 120 PSVNHSFELA PLDSHLVATS TTFHEASYES EPQQNPASQN IVLLLVSDGH TSYNNGANTF 130 140 150 160 170 180 EEAIQNRVDY STKQNYNFEY VNVTGLPIPA VWSKMPAVLQ TMKKYPKAEW IWLLDQDAII 190 200 210 220 230 240 TNTHLSLQDS FLKPENLQKT LITNTILTKR PINANGDLRY TPSNYSLKDI ENLMVIISQD 250 260 270 280 290 300 HNGLNAGSIL FRNSPATALF LDIWTDPVVA ECAKANNEQD MLGYLISKHS QLASLVGLIP 310 320 330 340 QRKINAFHEG PENMEWQKGD LVIHFAGCWV ENRCDELWQK FYALID

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CU329670 Genomic DNA. Translation: CAA89963.1.
PIR	S55491. T38977.
RefSeq	NP_592826.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2542227.
KEGG	spo:SPAC5H10.13c.
NMPDR	fig|4896.1.peg.2796.
Organism-specific databases
GeneDB_Spombe	SPAC5H10.13c.
Enzyme and pathway databases
BioCyc	SPOM-XXX-01:SPOM-XXX-01-000571-MON.
Gene expression databases
ArrayExpress	Q09681.
Family and domain databases
InterPro	IPR008630. Glyco_trans_34. [Graphical view]
Pfam	PF05637. Glyco_transf_34. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GMH2_SCHPO

Accession

Primary (citable) accession number: Q09681

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)