Reviewed, UniProtKB/Swiss-Prot Q0JQF7 (DRE2A_ORYSJ)

Names and origin

Protein names

Recommended name:
    Dehydration-responsive element-binding protein 2A
      Short name=Protein DREB2A

Gene names

Name:	DREB2A
Synonyms:	ERF40
Ordered Locus Names:	Os01g0165000, LOC_Os01g07120
ORF Names:	OsJ_000494

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription.
Subcellular location	NucleusProbable.
Induction	By high-salt and drought stresses.
Sequence similarities	Belongs to the AP2/ERF transcription factor family. ERF subfamily. Contains 1 AP2/ERF DNA-binding domain.
Sequence caution	The sequence EAZ10669.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Biological process	Stress response Transcription Transcription regulation
Cellular component	Nucleus
Ligand	DNA-binding
Molecular function	Activator
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 274	274	Dehydration-responsive element-binding protein 2A
Regions
	DNA binding	75 – 132	58	AP2/ERF
Experimental info
	Sequence conflict	81	1	Q → A in AK121956. Ref.6

Sequences

	Sequence		Length	Mass (Da)
	Q0JQF7-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: E7313A6FCB531B4F	FASTA	274	30,665
	10 20 30 40 50 60 MERGEGRRGD CSVQVRKKRT RRKSDGPDSI AETIKWWKEQ NQKLQEENSS RKAPAKGSKK 70 80 90 100 110 120 GCMAGKGGPE NSNCAYRGVR QRTWGKWVAE IREPNRGRRL WLGSFPTALE AAHAYDEAAR 130 140 150 160 170 180 AMYGPTARVN FADNSTDANS GCTSAPSLMM SNGPATIPSD EKDELESPPF IVANGPAVLY 190 200 210 220 230 240 QPDKKDVLER VVPEVQDVKT EGSNGLKRVC QERKNMEVCE SEGIVLHKEV NISYDYFNVH 250 260 270 EVVEMIIVEL SADQKTEVHE EYQEGDDGFS LFSY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"OsDREB genes in rice, Oryza sativa L., encode transcription activators that function in drought-, high-salt- and cold-responsive gene expression." Dubouzet J.G., Sakuma Y., Ito Y., Kasuga M., Dubouzet E.G., Miura S., Seki M., Shinozaki K., Yamaguchi-Shinozaki K. Plant J. 33:751-763(2003) [PubMed: 12609047] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INDUCTION, GENE FAMILY.
[2]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[5]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed: 15685292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[6]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[7]	"Structural, functional, and phylogenetic characterization of a large CBF gene family in barley." Skinner J.S., von Zitzewitz J., Szuecs P., Marquez-Cedillo L., Filichkin T., Amundsen K., Stockinger E.J., Thomashow M.F., Chen T.H.H., Hayes P.M. Plant Mol. Biol. 59:533-551(2005) [PubMed: 16244905] [Abstract] Cited for: GENE FAMILY. Strain: cv. Nipponbare.
[8]	"Genome-wide analysis of the ERF gene family in Arabidopsis and rice." Nakano T., Suzuki K., Fujimura T., Shinshi H. Plant Physiol. 140:411-432(2006) [PubMed: 16407444] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF300971 mRNA. Translation: AAN02487.2. AP008207 Genomic DNA. Translation: BAF04021.1. CM000138 Genomic DNA. Translation: EAZ10669.1. Sequence problems. AK121956 mRNA. No translation available.
RefSeq	NP_001042107.1.
UniGene	Os.32760
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4324418.
KEGG	osa:4324418.
Organism-specific databases
Gramene	Q8LLU9.
Family and domain databases
InterPro	IPR001471. TF_ERF_DNA-bd. [Graphical view]
Gene3D	G3DSA:3.30.730.10. TF_ERF. 1 hit.
Pfam	PF00847. AP2. 1 hit. [Graphical view]
PRINTS	PR00367. ETHRSPELEMNT.
ProDom	PD001423. TF_ERF. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00380. AP2. 1 hit. [Graphical view]
PROSITE	PS51032. AP2_ERF. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

DRE2A_ORYSJ

Accession

Primary (citable) accession number: Q0JQF7
Secondary accession number(s): A2ZPM2, Q8LLU9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	October 3, 2006
Last modified:	July 22, 2008
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)