Reviewed, UniProtKB/Swiss-Prot Q1KKZ4 (HXAAB_FUGRU)

Names and origin

Protein names

Recommended name:
    Homeobox protein Hox-A10b

Gene names

Name:

hoxa10b

Organism

Fugu rubripes (Japanese pufferfish) (Takifugu rubripes)

Taxonomic identifier

31033 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Tetraodontiformes › Tetradontoidea › Tetraodontidae › Takifugu

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.
Subcellular location	NucleusBy similarity.
Sequence similarities	Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 331	331	Homeobox protein Hox-A10b
Regions
	DNA binding	257 – 316	60	Homeobox

Sequences

	Sequence		Length	Mass (Da)
	Q1KKZ4-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: DDA1BA8C132C0BF9	FASTA	331	37,157
	10 20 30 40 50 60 MTCPNNQAGN SFFVDSLINV RPDSGSYYQS NGVYLPPGSE FSYGLSGGSC FPGIGKRNEP 70 80 90 100 110 120 SAQSVISSPA PYVQGMETWL EASRPCRVDQ PRGQHMAQCS FSPNIKEEST YCLYESDKCP 130 140 150 160 170 180 KGATVDDISY SASSCPVTST FPVPGYFRLS QTYASSRHYH DAHPNTDHFT LQQSARPDSR 190 200 210 220 230 240 SSHRQAASAE PEQRANREES PVCAPCVPVR EEDSRLSSEG SSSPEPAETP SLECPEKSGK 250 260 270 280 290 300 GDGKNETAAN WLTAKSGRKK RCPYTKHQTL ELEKEFLFNM YLTRERRLEI SRSVHLTDRQ 310 320 330 VKIWFQNRRM KLKKMTRENR IRELSNSFSF S

References

[1]

"Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters." Lee A.P., Koh E.G.L., Tay A., Brenner S., Venkatesh B. Proc. Natl. Acad. Sci. U.S.A. 103:6994-6999(2006) [PubMed: 16636282] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ481664 Genomic DNA. Translation: ABF22400.1.
3D structure databases
SMR	Q1KKZ4. Positions 245-318.
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q1KKZ4.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
ProDom	PD000010. Homeobox. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00389. HOX. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

HXAAB_FUGRU

Accession

Primary (citable) accession number: Q1KKZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	May 30, 2006
Last modified:	July 22, 2008
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)