Reviewed, UniProtKB/Swiss-Prot Q1ZXG3 (C522A_DICDI)

Names and origin

Protein names

Recommended name:
    Probable cytochrome P450 522A1
    EC=1.14.-.-

Gene names

Name:	cyp522a1
ORF Names:	DDB_0233031

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Cofactor	Heme group By similarity.
Subcellular location	Membrane; Single-pass membrane proteinPotential.
Sequence similarities	Belongs to the cytochrome P450 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Ligand	Heme Iron Metal-binding
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 489	489	Probable cytochrome P450 522A1
Regions
	Transmembrane	1 – 21	21	Potential
Sites
	Metal binding	433	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1ZXG3-1 [UniParc]. Last modified May 2, 2006. Version 1. Checksum: CE3785988C580061	FASTA	489	57,076
	10 20 30 40 50 60 MILTIVIIIL TVIFVNKYLL NNGGKNDLRK VQGPFNLPLL GALYAFDKER FHKSFDKFYD 70 80 90 100 110 120 KYKDFYFIKF GQHDCIVLNS PKLIKQVVIE QSDSVFERFH TPSIKRYAQG KSILGCSPDE 130 140 150 160 170 180 WKKLRSFIVI SFSKNKMGQQ VLDKIFHTQY LKFENHIKKL IKSNNNIVTL EPEFKRLTIS 190 200 210 220 230 240 IIFNFQFGTD LEFTDPLIDS LLVCTEKIIA SCQKASDLMP IFEIFTSYKD IDGVVKEMYA 250 260 270 280 290 300 LVKPFLEKYL KQHDRNNPKC ALDHMINCIL DQDEPKLITY EHLPHFLMDM FIGGTESTAR 310 320 330 340 350 360 TMDWFTLMMT NRKEMQDRIR TELLDVGIRL PVLVDKQKYP LLNASIKEIH RLRPIQPIIA 370 380 390 400 410 420 SRVVNDPIVL KHECSAKGES YTIPVGTLII PNAHSFNFDP QYHKDPLTFN PNRYIGDNPE 430 440 450 460 470 480 ILHMTFDIGI RTCPFMSFAI DELFIIFSRL FQSFEFQPID NTPISEEAFT INSIRPKQWS CQVIERDHK

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000047 Genomic DNA. Translation: EAS66867.1.
RefSeq	XP_001134550.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4238141.
KEGG	ddi:DDB_0233031.
Organism-specific databases
dictyBase	DDB0233031. cyp522a1.
Family and domain databases
InterPro	IPR001128. Cyt_P450. IPR002401. Cyt_P450_E_grp-I. [Graphical view]
Gene3D	G3DSA:1.10.630.10. Cyt_P450. 1 hit.
PANTHER	PTHR19383. Cyt_P450. 1 hit.
Pfam	PF00067. p450. 1 hit. [Graphical view]
PRINTS	PR00463. EP450I. PR00385. P450.
ProDom	Q1ZXG3. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

C522A_DICDI

Accession

Primary (citable) accession number: Q1ZXG3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	May 2, 2006
Last modified:	July 22, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)