Reviewed, UniProtKB/Swiss-Prot Q1ZXG4 (PRLA_DICDI)

Names and origin

Protein names

Recommended name:
    Proliferation-associated protein A

Gene names

Name:	prlA
ORF Names:	DDB_0232955

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the peptidase M24C family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 385	385	Proliferation-associated protein A
Experimental info
	Sequence conflict	380	1	I → T in AAB03665. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q1ZXG4-1 [UniParc]. Last modified May 2, 2006. Version 1. Checksum: 69DB4B686234C58E	FASTA	385	42,306
	10 20 30 40 50 60 MSNKDQEIKE EAPVAIEDLS NPVVVDSYNA AGIIANNAIK HVISKCVVGA LVVDICQYGD 70 80 90 100 110 120 DFIEAEAAKT FTKRKNLEKG IAFPTCVSVN NCVGHFSPLK GNTRTLKQGD VVKIDLGCHI 130 140 150 160 170 180 DGYIAVGAHT IIIGNTSAES MTGKVADAIC AAHYALEAAL RMIRPGKTSN EVTQVIEKIS 190 200 210 220 230 240 DMYGVTSVSG ILSHELKRFI IDGEKVIFSK NEPSQKIQTY EFQENEVYCI DIVMSTGEGK 250 260 270 280 290 300 AREEADRPTI YRRNLDSTYK LKSKASRDFK DQIVKRYSAL PFPLRNFDEK VSKLGLVELV 310 320 330 340 350 360 EHQVLAAYPV LFDRSGCEVV QFKTTVLVLP NGNHKLIGTE FPLPFVRSEF SVTDDAIKAL 370 380 IASPLKINKK AAKKASATTI DVKMQ

References

[1]

"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

[2]

"Ordered yeast artificial chromosome clones representing the Dictyostelium discoideum genome." Kuspa A., Loomis W.F. Proc. Natl. Acad. Sci. U.S.A. 93:5562-5566(1996) [PubMed: 8643615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-385. Strain: AX4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AAFI02000047 Genomic DNA. Translation: EAS66866.1. U61403 mRNA. Translation: AAB03665.1.
RefSeq	XP_001134549.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4238140.
KEGG	ddi:DDB_0232955.
Organism-specific databases
dictyBase	DDB0232955. prlA.
Family and domain databases
InterPro	IPR004545. Pap_1. IPR001714. Pept_M24_MAP. IPR000994. Peptidase_M24_cat_core. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
PANTHER	PTHR10804. Peptidase_M24_cat_core. 1 hit.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
TIGRFAMs	TIGR00495. crvDNA_42K. 1 hit.
ProDom	Q1ZXG4. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

PRLA_DICDI

Accession

Primary (citable) accession number: Q1ZXG4
Secondary accession number(s): Q23918

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	May 2, 2006
Last modified:	September 23, 2008
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)