Reviewed, UniProtKB/Swiss-Prot Q2MJS5 (MT3_BOSMU)

Names and origin

Protein names

Recommended name:
    Metallothionein-3
      Short name(s)=MT-3
Alternative name(s):
    Metallothionein-III
      Short name(s)=MT-III

Gene names

Name:

MT3

Organism

Bos mutus grunniens (Wild yak) (Bos grunniens)

Taxonomic identifier

30521 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length	68 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Binds heavy metals. Contains five zinc and one copper atoms per polypeptide chain and only a negligible amount of cadmium By similarity.
Sequence similarities	Belongs to the metallothionein superfamily. Type 1 family.

Ontologies

Keywords
Ligand	Copper Metal-binding Metal-thiolate cluster Zinc
PTM	Acetylation
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 68	68	Metallothionein-3
Regions
	Region	1 – 30	30	Beta
	Region	31 – 68	38	Alpha
Sites
	Metal binding	6	1	Cluster B By similarity
	Metal binding	8	1	Cluster B By similarity
	Metal binding	14	1	Cluster B By similarity
	Metal binding	16	1	Cluster B By similarity
	Metal binding	20	1	Cluster B By similarity
	Metal binding	22	1	Cluster B By similarity
	Metal binding	25	1	Cluster B By similarity
	Metal binding	27	1	Cluster B By similarity
	Metal binding	34	1	Cluster A By similarity
	Metal binding	35	1	Cluster A By similarity
	Metal binding	37	1	Cluster A By similarity
	Metal binding	38	1	Cluster A By similarity
	Metal binding	42	1	Cluster A By similarity
	Metal binding	45	1	Cluster A By similarity
	Metal binding	49	1	Cluster A By similarity
	Metal binding	51	1	Cluster A By similarity
	Metal binding	64	1	Cluster A By similarity
	Metal binding	66	1	Cluster A By similarity
	Metal binding	67	1	Cluster A By similarity
Amino acid modifications
	Modified residue	1	1	N-acetylmethionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2MJS5-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 1DD24B83AA52AE71	FASTA	68	6,937
	10 20 30 40 50 60 MDPETCPCPT GGSCTCSDPC KCEGCTCASS KKSCCSCCPA ECEKCAKDCV CKGGEGAEAE EKKCSCCQ

References

[1]	"Bos grunniens metallothionein-3." Liu B.P., Wu J.P., Ma B.Y., Zhang L.P., Yang L., Gao F.Q. Gansu Nong Ye Da Xue Xue Bao 40:5-10(2006) Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ492300 mRNA. Translation: ABC50101.1.
3D structure databases
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q2MJS5.
Family and domain databases
InterPro	IPR015874. 4-disulphide_core. IPR001450. 4Fe4S_Fe_S_bd. IPR003019. Metallothionein_sfam_euk. IPR000006. Metallothionein_vert. [Graphical view]
Gene3D	G3DSA:4.10.10.10. Metallothionein_vert. 1 hit.
PANTHER	PTHR23299. Metallothionein_vert. 1 hit.
Pfam	PF00131. Metallothio. 1 hit. [Graphical view]
PRINTS	PR00003. 4DISULPHCORE. PR00353. 4FE4SFRDOXIN. PR00860. MTVERTEBRATE.
PROSITE	PS00203. METALLOTHIONEIN_VRT. False negative. [Graphical view]
ProDom	Q2MJS5. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

MT3_BOSMU

Accession

Primary (citable) accession number: Q2MJS5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	February 7, 2006
Last modified:	July 22, 2008
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)