Reviewed, UniProtKB/Swiss-Prot Q3UPI1 (CD018_MOUSE)

Names and origin

Protein names	Recommended name:     Uncharacterized protein C4orf18 homolog
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	517 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location

Golgi apparatus membrane; Single-pass type II membrane proteinBy similarity.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane
PTM	Glycoprotein
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 517	517	Uncharacterized protein C4orf18 homolog
Regions
	Topological domain	1 – 36	36	Cytoplasmic Potential
	Transmembrane	37 – 56	20	Signal-anchor for type II membrane protein Potential
	Topological domain	57 – 517	461	Extracellular Potential
Amino acid modifications
	Glycosylation	98	1	N-linked (GlcNAc...) Potential
	Glycosylation	287	1	N-linked (GlcNAc...) Potential
Experimental info
	Sequence conflict	275	1	V → L in AAH56975. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q3UPI1-1 [UniParc]. Last modified October 11, 2005. Version 1. Checksum: FA7B56FA8E3A85A5	FASTA	517	58,298
	10 20 30 40 50 60 MTCPDKPGQL VNWFVCSLCA PRVCKLWSSR RPRTRRNLLL GTACAIYLGF LVSQVGRGSF 70 80 90 100 110 120 QHGQATDRGP PNGHDIFKVP FSEIPLDGTL APPELQGNGS TLQPNVVYIT LRSKRSKPAN 130 140 150 160 170 180 IRGTVKPKRR KKYAVASAAP DQEVLVRPSL IQQEAARAAD AEVPGYVQGY LTKVGERPWR 190 200 210 220 230 240 VLRGPGVRTR GSNLQQPRAR ESNIRIYSES APSWLSKEDI RRMRLLADSE VASILPISKS 250 260 270 280 290 300 GTRLLVLEGS TSGSVPGCGP SPCGLLKQPL DMSEVFAFHL DRILGLNRTL PSVSRKLEFI 310 320 330 340 350 360 QDGRPRPIIL WDSSLASASN DSHSSVKITW GTYQRLLKQK CWLNGRVPRP EWDCTEIHHH 370 380 390 400 410 420 EWSKMALFDF LLQIYNRLDT NCCGFRPRKE DACIQNGLRS NCEDQTSVTL AHIIQRKNDP 430 440 450 460 470 480 RHLVFINNKG FFDRSEDNLN FKLLEGIREF PESAVSVLKS QHLRQKLLQS LFLDQVYWES 490 500 510 QGGRQGIEKL IDVIERRARI LITYINAHGA RVLPMNE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Differentially expressed genes in AKR-2B fibroblasts." Hoppe J., Hoppe V. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Embryo and Heart.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6. Tissue: Brain.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF285091 mRNA. Translation: AAG00502.1. AK052367 mRNA. Translation: BAC34959.1. Different initiation. AK143522 mRNA. Translation: BAE25414.1. BC056975 mRNA. Translation: AAH56975.1.
RefSeq	NP_573450.2.
UniGene	Mm.427274 Mm.467899
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSMUSG00000027955. Mus musculus. [Contig view]
GeneID	68659.
KEGG	mmu:68659.
NMPDR	fig|10090.3.peg.8216.
Organism-specific databases
MGI	MGI:1915909. 1110032E23Rik.
Phylogenomic databases
HOGENOM	Q3UPI1.
HOVERGEN	Q3UPI1.
Gene expression databases
ArrayExpress	Q3UPI1.
CleanEx	MM_1110032E23RIK.
Family and domain databases
ProDom	Q3UPI1. [Graphical view] [Entries sharing at least one domain]
BLOCKS	Search...
Other Resources
ProtoNet	Search...

Entry information

Entry name

CD018_MOUSE

Accession

Primary (citable) accession number: Q3UPI1
Secondary accession number(s): Q6PGJ9, Q8C781, Q9ET25

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	October 11, 2005
Last modified:	September 2, 2008
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)