Reviewed, UniProtKB/Swiss-Prot Q4UN76 (OXAA_RICFE)

Names and origin

Protein names

Recommended name:
    Inner membrane protein oxaA

Gene names

Name:	oxaA
Ordered Locus Names:	RF_0131

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	560 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex By similarity.
Subunit structure	Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane proteinBy similarity.
Sequence similarities	Belongs to the OXA1/oxaA family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein insertion into membrane Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 560	560	Inner membrane protein oxaA HAMAP MF_01810		PRO_0000272371
Regions
	Transmembrane	5 – 25	21	Potential
	Transmembrane	334 – 354	21	Potential
	Transmembrane	357 – 377	21	Potential
	Transmembrane	431 – 451	21	Potential
	Transmembrane	476 – 496	21	Potential
	Transmembrane	522 – 542	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q4UN76-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: F19BA53348557CBB	FASTA	560	64,462
	10 20 30 40 50 60 MNNNIINLIA AIILSLSIIF GWQYFVVKPE QKKQQQQIAV QKAENLKKQQ LKALVEPATD 70 80 90 100 110 120 IVVQEESGVQ RIKIESESLT GSISLKGLRF DDLILKKYKQ DLSNNSPEVR LFSPANTENA 130 140 150 160 170 180 YFAEIGLVSN LSSVKLPNND TIWNSDSEIL SPEKPVNLFW VNEDGVKFLV TITVDENYLF 190 200 210 220 230 240 TIEQTIVNNS DKELPIQSYG LINRKYTAVE KAVNILHQGP IGCIDENLKE YSYDDIKDKK 250 260 270 280 290 300 SEKFAASKVD WIGITDKYWL SSLIPDKSSN YSSNFNYALK QGTERYQVDF ISPVQIIKPG 310 320 330 340 350 360 ENFSIKSRIF AGAKKVDLLD KYEKQYDIKL FDRAIDFGWF YIITKPVFYA MNFFYGYVGN 370 380 390 400 410 420 FGVSILIVTV IIKLLMFTLA NKSYRSMKKM KNLQPEIDRI KNLYSDDKAR LNQEIMALYK 430 440 450 460 470 480 KEKVNPVAGC LPILVQIPLF FSIYKVLYVT IEMRQVPFYG WIKDLSAPDP TTIFNLFGLL 490 500 510 520 530 540 PFSPPSFLMI GAWPILMAIT MFLQQKMSPE PADPMQAQVM KFMPLIFLFM FSSFPVGLLI 550 560 YWSWNNILSI IQQYYINKFN

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY60982.1.
RefSeq	YP_246147.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3400842.
GenomeReviews	Gene locus RF_0131 in contig CP000053_GR.
KEGG	rfe:RF_0131.
NMPDR	fig|315456.3.peg.650.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UN76.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0131-MON.
Family and domain databases
HAMAP	MF_01810. [Tree]
InterPro	IPR001708. Innermemb_insert. IPR013308. YidC. [Graphical view]
PANTHER	PTHR12428. Innermemb_insert. 1 hit.
Pfam	PF02096. 60KD_IMP. 1 hit. [Graphical view]
PRINTS	PR00701. 60KDINNERMP. PR01900. YIDCPROTEIN.
ProtoNet	Search...

Entry information

Entry name

OXAA_RICFE

Accession

Primary (citable) accession number: Q4UN76

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	July 5, 2005
Last modified:	November 25, 2008
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)