Reviewed, UniProtKB/Swiss-Prot Q4UNB0 (ACKA_RICFE)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	RF_0097

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 385	385	Acetate kinase HAMAP MF_00020		PRO_0000272341

Sequences

	Sequence		Length	Mass (Da)
	Q4UNB0-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 5F3FB3EEB826CAB1	FASTA	385	43,247
	10 20 30 40 50 60 MKDVILIANA GSSSLKISIF EIQNKKVKDK IYNIFLEKNV NKILFHINKK QESATDIKDD 70 80 90 100 110 120 AIEMMIDLFE DWWKKQENLN LIATGHRIVH GGKNFNKPVI VYEKVSKDLT VLIPLSPLHQ 130 140 150 160 170 180 PYNLQVLDLF LQKYKEISHI ACFDTSFHFT NPPITKAFGL PKKYYDKGII RYGFHGLSYK 190 200 210 220 230 240 YVSSHFKEMT KEDLPTKTII AHLGSGSSLC AIKNGLSLTS SMGFSVLDGV MMGTRTGNLD 250 260 270 280 290 300 PGVVLYLIDH EKMTTKEVTE LLYKKSGLLG MSGESSDMRT LLASNSPDAK FAIDLFVYRI 310 320 330 340 350 360 VLEIGKLTAA LEGVDCLIFT AGVGQNSAVI RKMITEKLLW LGIKIDDTKN QKNEHLISTS 370 380 DSKVKVFAVP TNEELIIAEE VMKFL

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY60948.1. Different initiation.
RefSeq	YP_246113.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3401066.
GenomeReviews	Gene locus RF_0097 in contig CP000053_GR.
KEGG	rfe:RF_0097.
NMPDR	fig|315456.3.peg.616.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UNB0.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0097-MON.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate_kin. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_RICFE

Accession

Primary (citable) accession number: Q4UNB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	November 25, 2008
This is version 23 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)