Reviewed, UniProtKB/Swiss-Prot Q4UND7 (EFTS_RICFE)

Names and origin

Protein names

Recommended name:
    Elongation factor Ts
      Short name=EF-Ts

Gene names

Name:	tsf
Ordered Locus Names:	RF_0070

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. HAMAP MF_00050
Subcellular location	Cytoplasm. HAMAP MF_00050
Sequence similarities	Belongs to the EF-Ts family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Elongation factor Ts HAMAP MF_00050		PRO_0000241522
Regions
	Region	82 – 85	4	Involved in Mg(2+) ion dislocation from EF-Tu By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4UND7-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 0B6F77572CF8F44A	FASTA	309	33,805
	10 20 30 40 50 60 MSEINISAAA VKELREKTGA GMMDCKKALI ETSGNFEEAI DFLRKKGLAA AAKKAGRIAS 70 80 90 100 110 120 EGLTAAKVDG LTGVVVEVNS ETDFVARNEQ FQDLVKDIAN LAVIAKTIDT LKTSKMQSGK 130 140 150 160 170 180 SVEEEIIENI ATIGENLTLR RMDILEISEG AIGSYVHNEV VPNLGKISVL VGLESNAKDK 190 200 210 220 230 240 TKLEALAKQV AVHVAGNNPQ SIDDSSLDQA LVERERKVFF EKSKEEGKPD NIIEKMVEGR 250 260 270 280 290 300 IRKFFSEVVL LQQNFLFEPK LTVAEVIKNA EKELGAEIKI AKFIRYELGE GIEHEEKNFA DEVAAITQG

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY60921.1.
RefSeq	YP_246086.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3400300.
GenomeReviews	Gene locus RF_0070 in contig CP000053_GR.
KEGG	rfe:RF_0070.
NMPDR	fig|315456.3.peg.552.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UND7.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0070-MON.
Family and domain databases
HAMAP	MF_00050. [Tree]
InterPro	IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR000449. UBA/transl_elong_EF1B_N. [Graphical view]
Gene3D	G3DSA:3.30.479.20. Transl_elong_EFTs/EF1B_dimer. 2 hits.
PANTHER	PTHR11741. Transl_elong_EFTs/EF1B. 1 hit.
Pfam	PF00889. EF_TS. 1 hit. PF00627. UBA. 1 hit. [Graphical view]
TIGRFAMs	TIGR00116. tsf. 1 hit.
PROSITE	PS01126. EF_TS_1. 1 hit. PS01127. EF_TS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFTS_RICFE

Accession

Primary (citable) accession number: Q4UND7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	July 5, 2005
Last modified:	November 4, 2008
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)