Reviewed, UniProtKB/Swiss-Prot Q4UNE0 (SCA2_RICFE)

Names and origin

Protein names

Recommended name:
    Putative surface cell antigen sca2

Gene names

Name:	sca2
Ordered Locus Names:	RF_0067

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	1604 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell outer membraneBy similarity.
Sequence similarities	Contains 1 autotransporter (TC 1.B.12) domain. [View classification]

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 33	33	Potential
	Chain	34 – 1604	1571	Putative surface cell antigen sca2		PRO_0000262570
Regions
	Domain	1325 – 1604	280	Autotransporter
	Compositional bias	567 – 586	20	Pro-rich

Sequences

	Sequence		Length	Mass (Da)
	Q4UNE0-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: AEDF32AE861BB416	FASTA	1,604	182,803
	10 20 30 40 50 60 MSLQNSHSKK YVLTFFMSTC LLTSSFLSTS ARAASFTQLA NQIPTLSGLS EVQRKQKWNS 70 80 90 100 110 120 YTLQEKQEAW RRAKLTPDFV QAMIDMQTGF TESDLSSRNN KTRHKAREKK SELDLYIAGT 130 140 150 160 170 180 KQGFKEKVDG YISQGKIPTP EEAAQNLEID YDAKKTDNKL EKNQNVRRVE KDKKALLDLY 190 200 210 220 230 240 IHSITTSVKE KEYITTGQVP ELGELEKALN ISKEEAKHRR TIIRDQVMAN ERPKLVRSGT 250 260 270 280 290 300 VLTKKELHKR FGKDTTTDDT KYIDDITTEV MYTKKQGYVN TDFLPKISEI MNEFKVDKGR 310 320 330 340 350 360 ANLYLNQIKA GIEAKLLADN NQTTTKPFTK HSRTTTNTAG ISSGVPFDTG RTKPETKSFD 370 380 390 400 410 420 FKRSMYSLLN RKQEDQLSKT EQHLKQQIKL EENKEEFKEI LTKNPIDALL FAEQSNLGNS 430 440 450 460 470 480 FKQEAISNID LSKDISRILF TVDDKGNRTI LNTILTTTPE HKDELIKQAQ HHAIQTLPTS 490 500 510 520 530 540 ISDKDVSDKK KLTLATLAAT EDKKVLEEAL DNWLSTNGYK RKPEVESLIS ILLSDETTLK 550 560 570 580 590 600 AGIDKIFELP VENNVNNNSN KGQNGTPILP PTPPLNGSMP PSPPPPLLNG TPTSTAFNNS 610 620 630 640 650 660 NPNHKFDLKN FEATYPRLYK SYNEFIQNTT SASQSQATTT SNNIPDTKAK MGESLELLKQ 670 680 690 700 710 720 KVAKQNEVIG LIHNEVTKLY NFSPKTFVNL FNTENEEIIK KIEQIAKRED IQKILQDNDI 730 740 750 760 770 780 KITSTFVSKI FNESLEQTKQ RLRSSNIINA KQYKRIEQYA NKQECVTEFL RITNPLEQLK 790 800 810 820 830 840 FANKYINILG QSTFNGKLNE LIENPNKLTF SQKINFVLQG YQELTREIPT AKANLNKLKQ 850 860 870 880 890 900 NILEKIEIQQ LIANKDISRK DLLDILNNKN PELLKSLLEA KVILEENKLN NSANEVDLKE 910 920 930 940 950 960 IIPSLNYLTS EQLTSLINRI TIEGVKTALK AKWQQENKTV SNNTEKPLIY NNGTPMPPPI 970 980 990 1000 1010 1020 PNGNSNFGTN DYLISMGYTQ EFIDRMDKVK PNNNFGKNHN YTATDFKSNV GKNYYESTSK 1030 1040 1050 1060 1070 1080 LGGTDILLTD SQKLENAIKK EVLAKYIEEP NRDMQDDSLL KQAFEEKFYY AEDKNTKVIP 1090 1100 1110 1120 1130 1140 KPSEVNFDPN FIGPRTEVGQ EIYELYEQEL LKLARDPVFI EYVKNNNNTQ KDERELLISF 1150 1160 1170 1180 1190 1200 IEQIESKRPE LEQKYGSDVQ SEDNNQEKKV GHLNMKQFQS LFQQENESAN DESSTKDDPQ 1210 1220 1230 1240 1250 1260 PEDSNKKSEK SDSETALSPR LLSSNDSKND KSSDDKKSLL VLRSSEEESK KDIALESEDE 1270 1280 1290 1300 1310 1320 AIDMSFKTEA IAEQDEATQR QQVSDDTNRK VAILVKATST LHKPVHYNIL SDRLKVAAIG 1330 1340 1350 1360 1370 1380 AGDEEASINR GVWISGLYGI NKQGTWKNIP KYQGRTTGVT IGADAEFINS HDVIGIAYSR 1390 1400 1410 1420 1430 1440 LEFQIKYNKK LEKTAVNGHL LSIYGLKELI KGFSLQAITS YGHNYIKNKS KSINNIIGKY 1450 1460 1470 1480 1490 1500 QNNNLSFQTL LNYKYRTKYD LHFIPNIGFK YDYSRASNYK EYNVDIENLM NQKKSNQSFE 1510 1520 1530 1540 1550 1560 SSIGGKIVFK PIATVNNIIL TPSLYGNIER HFNNKNTKVN AKATFKGQTL QETIIIPKQP 1570 1580 1590 1600 KLGYNIGSNI LMSKKNINVL LEYNYYTHRK YQSHQGLIKL KVNL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Phylogenetic study of Rickettsia species using sequences of the autotransporter protein-encoding gene sca2." Ngwamidiba M., Blanc G., Ogata H., Raoult D., Fournier P.-E. Ann. N. Y. Acad. Sci. 1063:94-99(2005) [PubMed: 16481498] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY355374 Genomic DNA. Translation: AAT79539.1. CP000053 Genomic DNA. Translation: AAY60918.1.
RefSeq	YP_246083.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3400297.
GenomeReviews	Gene locus RF_0067 in contig CP000053_GR.
KEGG	rfe:RF_0067.
NMPDR	fig|315456.3.peg.549.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UNE0.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0067-MON.
Family and domain databases
InterPro	IPR005546. Auto_transptbeta. IPR006315. OM_autotransptr_brl. [Graphical view]
Pfam	PF03797. Autotransporter. 1 hit. [Graphical view]
TIGRFAMs	TIGR01414. autotrans_barl. 1 hit.
PROSITE	PS51208. AUTOTRANSPORTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCA2_RICFE

Accession

Primary (citable) accession number: Q4UNE0

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	July 5, 2005
Last modified:	November 4, 2008
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)