Reviewed, UniProtKB/Swiss-Prot Q4UNF3 (DCD_RICFE)

Names and origin

Protein names

Recommended name:
    Deoxycytidine triphosphate deaminase
      Short name=dCTP deaminase
    EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	RF_0054

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	dCTP + H(2)O = dUTP + NH(3). HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000274885

Sequences

	Sequence		Length	Mass (Da)
	Q4UNF3-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 8B276D27E6A0F6BD	FASTA	188	21,319
	10 20 30 40 50 60 MAIMSDKWIK EAVINQSMIR PFAEKQVRVH NKEKIISYGL SSYGYDARVS NEFKIFTNIN 70 80 90 100 110 120 STTVDPKNFS EYNLVDREVD VCIIPPNSFA LGRTIEYFKI PRDVLVICVG KSTYARCGII 130 140 150 160 170 180 VNVTPLEPEW EGHVTLEFSN TTPLPAKIYA NEGACQFLFL KSDQICDTSY ADRQGKYMKQ VGVTLPLT

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY60905.1.
RefSeq	YP_246070.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3401237.
GenomeReviews	Gene locus RF_0054 in contig CP000053_GR.
KEGG	rfe:RF_0054.
NMPDR	fig|315456.3.peg.536.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UNF3.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0054-MON.
Family and domain databases
HAMAP	MF_00146. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
ProDom	PD004900. dCTP_deaminase. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_RICFE

Accession

Primary (citable) accession number: Q4UNF3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	July 5, 2005
Last modified:	November 25, 2008
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)