Reviewed, UniProtKB/Swiss-Prot Q4UNH9 (ATPL_RICFE)

Names and origin

Protein names

Recommended name:
    ATP synthase C chain
    EC=3.6.3.14
Alternative name(s):
    Lipid-binding protein

Gene names

Name:	atpE
Ordered Locus Names:	RF_0029

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	74 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	This is one of the four chains of the nonenzymatic component (CF(0) subunit) of the ATPase complex.
Catalytic activity	ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
Subunit structure	F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
Subcellular location	Cell membrane; Multi-pass membrane proteinPotential.
Sequence similarities	Belongs to the ATPase C chain family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Cellular component	CF(0) Cell membrane Membrane
Domain	Transmembrane
Ligand	Lipid-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW proton-transporting ATP synthase complex, coupling factor F(o) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro hydrogen ion transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro lipid binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 74	74	ATP synthase C chain		PRO_0000288729
Regions
	Transmembrane	9 – 29	21	Potential
	Transmembrane	52 – 72	21	Potential
Sites
	Site	58	1	Reversibly protonated during proton transport By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q4UNH9-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 43844F903C4A0C65	FASTA	74	7,686
	10 20 30 40 50 60 MDMVSLKFIG IGLMAIGMYG AALGVSNIFS SLLSSIARNP SAAENLQRMA LIGAGLAEAM 70 GLFSFVIAML LIFS

References

[1]

"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY60880.1.
RefSeq	YP_246045.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3401255.
GenomeReviews	Gene locus RF_0029 in contig CP000053_GR.
KEGG	rfe:RF_0029.
NMPDR	fig|315456.3.peg.511.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UNH9.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0029-MON.
Family and domain databases
InterPro	IPR002379. ATPase_F0/V0_c. IPR000454. ATPase_F0_c. [Graphical view]
Gene3D	G3DSA:1.20.20.10. ATPase_F0/V0_c. 1 hit.
Pfam	PF00137. ATP-synt_C. 1 hit. [Graphical view]
PRINTS	PR00124. ATPASEC.
PROSITE	PS00605. ATPASE_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPL_RICFE

Accession

Primary (citable) accession number: Q4UNH9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	July 5, 2005
Last modified:	November 25, 2008
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)