Reviewed, UniProtKB/Swiss-Prot Q4UNI5 (SCA1_RICFE)

Names and origin

Protein names

Recommended name:
    Putative surface cell antigen sca1

Gene names

Name:	sca1
Ordered Locus Names:	RF_0022

Organism

Rickettsia felis (Rickettsia azadi) [Complete proteome] [HAMAP]

Taxonomic identifier

42862 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	1703 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell outer membraneBy similarity.
Sequence similarities	Contains 1 autotransporter (TC 1.B.12) domain. [View classification]

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 1703	1675	Putative surface cell antigen sca1		PRO_0000259743
Regions
	Domain	1419 – 1703	285	Autotransporter
	Compositional bias	304 – 388	85	Lys-rich

Sequences

	Sequence		Length	Mass (Da)
	Q4UNI5-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: DD34C843ED76C7AB	FASTA	1,703	188,879
	10 20 30 40 50 60 MNKLTEQNLL KKSRFLKYSL LASISVGAII AIPFEGMASS KQKALFQNAL EKKLSLRLSQ 70 80 90 100 110 120 SNGNRDTTNT PQQIGTVIVP EPERNTYTSS EIREMEISKQ SKASNPLKDI PIEDHYKKVA 130 140 150 160 170 180 RSKSDVGKAR KVRPPTRSKT FVDTEKVEQN QNNYTHEPTE QTPQKPEIII TASSPTVSPA 190 200 210 220 230 240 SNGFVTAPNT PNTTLTSPEH YTTAPGTPST PVTPYQPTPD SKPNDNLEAK TPPNTNSKAV 250 260 270 280 290 300 RRLSFSSEPQ QTVVQPSTQA KPPVPPKPLL LSSAGVVAKK VVSNILRVNE MLGIKLAEVE 310 320 330 340 350 360 STIKNTQGKE NKKPLQQLKK QIASSQKTTE KLKSEAAKIG IKIKELDEEN KSLKTGRVKN 370 380 390 400 410 420 KRELDKDNAK LKENNKKIDK LQQKLTNKNN EANRLSEEID ISVKKVVLIK PQVKAPVTEM 430 440 450 460 470 480 PPAGSFLNQQ QQLEVLTQQQ KVNAARQAVV DKKRAEANGV KRNSAEYKDL ISEREEIQLE 490 500 510 520 530 540 QNQRHIAVEK TKKQQQAEDK EQRQEAQKQL SKIKKQEKAI KAASDEAQKI LNDAKKEASR 550 560 570 580 590 600 TKLKKLQEQM DNHVAMVTND KIEENIKKLE GLALTPSTTS SAATISKQSL TAKSTMQLSH 610 620 630 640 650 660 ELQRTLPEDE DGYLEPIKVQ QQPYTVMLSN QEVADPKSMD SGLGSLPSGI ETDEDTEFNL 670 680 690 700 710 720 GWGNGHHKEL ILSVDSKLIE KAAQLISGLD VKRSEILQTT SPSQQKSLNL ALQGIENDYQ 730 740 750 760 770 780 EAIEVYQGLQ QALIHKSEDI KAYNAEAEKR LDAIKSRADK YFNNIETDAD VGFNQDWSNV 790 800 810 820 830 840 HTQTAQSDSV LKMQQALLEK RSKEGSNPNF TTYLDPQPGE EGLKSIDSGL GSLPIDASVI 850 860 870 880 890 900 PQYVEELNNL ASFSSLNQIQ QKKPLIITNM LLSETSALSD DEFRAVANEV HPKIRPILTY 910 920 930 940 950 960 NRQKEKEAKL VEAEAAHSQV VQNAIKTPNS TQAKEAVENA AKLFGQYNNS FKLTQALRDE 970 980 990 1000 1010 1020 HRKKYYETPK KVTDSINSLD LAVPAESQQL KEPRSKSLEA LDLAGSVSSQ LKQAEYKSVL 1030 1040 1050 1060 1070 1080 SPSSSVNSLL SNEDEQNHEF EIPKSLSFSF GSLNSDAESQ QLKEPRSKSL EALDLAGSVS 1090 1100 1110 1120 1130 1140 SQLKQAEYKS VLSPSSSVNS LFSNEDEQNH EFEILKSLSF SFGSLNSDAE SNLSWDNTGD 1150 1160 1170 1180 1190 1200 IGVGHRYGAE DSCPTPDQSS SKIANSSDKN SSETKLALLR TYQMAVIVKR QELEQLPSTS 1210 1220 1230 1240 1250 1260 SGADQNTQKI KELKEVEVTM HDAINACIAD SSKLNDVSFE EINEALKKLG SEIPESAISD 1270 1280 1290 1300 1310 1320 FESKAQKDPE AILDGSILQE MLSSKDSLPS GDEEQEDTEV TESGIQKAGD KGLLALPVSS 1330 1340 1350 1360 1370 1380 NECALALSDG REKECLALGD GSEEKEETIE QLSDSVEGNL KIEQEEKKEM QTQISKNAPT 1390 1400 1410 1420 1430 1440 LNQAKVVNTI VNNMIRNRLD ASMNMSNNMV AVGAGDEEES RIKRGLWMRG MYGTNNHGRV 1450 1460 1470 1480 1490 1500 ENMTGYRGTN KGATIGFDVE IDNNILGIAY SNVHSVFKFK NSKNNDKELI DSHVVSIYGQ 1510 1520 1530 1540 1550 1560 KELPRNFALQ ALVSASKNFI KDKTTYSYGD TKIRSNVKHS NHSYNAEALL NYNYLLQNKL 1570 1580 1590 1600 1610 1620 VITPNIGLRY GKSRDGVYNE TGINVQEIAL TMKENNILSG IVGTKVKVPL KDVLKFNNLG 1630 1640 1650 1660 1670 1680 LTFQGAVEHN FKEKTQRINR VVKIFDTEFK QNYAIPKQPK TSYNLGTGII GSIKNTTISL 1690 1700 DYNYYLNKHY RSHQGSVKLK VNL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite." Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E., Parinello H., Claverie J.-M., Raoult D. PLoS Biol. 3:1-12(2005) [PubMed: 15984913] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-1525 / URRWXCal2.
[2]	"Sca1, a previously undescribed paralog from autotransporter protein-encoding genes in Rickettsia species." Ngwamidiba M., Blanc G., Raoult D., Fournier P.-E. BMC Microbiol. 6:12-12(2006) [PubMed: 16504018] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1430-1591, TRANSCRIPTION. Strain: ATCC VR-1525 / URRWXCal2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000053 Genomic DNA. Translation: AAY60873.1. DQ306907 Genomic DNA. Translation: ABC41077.1.
RefSeq	YP_246038.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3400293.
GenomeReviews	Gene locus RF_0022 in contig CP000053_GR.
KEGG	rfe:RF_0022.
NMPDR	fig|315456.3.peg.504.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q4UNI5.
Enzyme and pathway databases
BioCyc	RFEL315456:RF_0022-MON.
Family and domain databases
InterPro	IPR005546. Auto_transptbeta. IPR006315. OM_autotransptr_brl. [Graphical view]
Pfam	PF03797. Autotransporter. 1 hit. [Graphical view]
TIGRFAMs	TIGR01414. autotrans_barl. 1 hit.
PROSITE	PS51208. AUTOTRANSPORTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCA1_RICFE

Accession

Primary (citable) accession number: Q4UNI5
Secondary accession number(s): Q20DN4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2006
Last sequence update:	July 5, 2005
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)