Unreviewed, UniProtKB/TrEMBL Q4W6B5 (Q4W6B5_DICDI)

Names and origin

Protein names

Submitted name:
    Beta subunit of mitochondrial processing peptidase (Mitochondrial processing peptidase beta subunit) EMBL BAD98567.1

Gene names

Name:	mppb EMBL BAD98567.1
Synonyms:	mppB EMBL EAS66835.1
ORF Names:	DDB_0231799 EMBL EAS66835.1

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome] EMBL BAD98567.1

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	469 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the peptidase M16 family. RuleBase RU004447V0

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4W6B5-1 [UniParc]. Last modified July 5, 2005. Version 1. Checksum: 404154C4C47DF92D	FASTA	469	52,626
	10 20 30 40 50 60 MSNITKLFVK STKNFSRSFS RKTVDPSYLK ISPETKITTL SNGIRVATEQ TYGEVASVGV 70 80 90 100 110 120 WVDSGSVYET DKNNGVAHFL EHMIFKGTAK RPTPQSIETE IENMGGSLNA FTSREHSAYY 130 140 150 160 170 180 MKVLKDNVPN AVDILSDILQ NSKFETSLIE QERDTILSEN DYIQSKEDEV VFDQLHAAAF 190 200 210 220 230 240 QGSALGRTIL GPVENIKSIT REQIQEFINE NYTGDRLVIS AAGAVNHEQL VEQVKEKFAN 250 260 270 280 290 300 VKMSQVSKDV KRAAITNDFI GSELRVRDDE QPLIHFAVAV RALPWTDPDY FVLELIQTMI 310 320 330 340 350 360 GNWNRGIAAG KNIASNLGEI VATEDLAESY STFFTCYQDT GLFGNYGVCQ PERVDDLVAE 370 380 390 400 410 420 MLKEWQRIAT SCNKNEVERN KQKLLATTLM QYDGTSKVCE GIGRQILTLG RRLSPFEVYT 430 440 450 460 RINEITVADV QRVASTLLRD VSPAVTAIGP IANYPDYNFV KGWTYWNRL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Antisense RNA inhibition of the beta subunit of the Dictyostelium discoideum mitochondrial processing peptidase induces the expression of mitochondrial proteins." Nagayama K., Itono S., Yoshida T., Ishiguro S., Ochiai H., Ohmachi T. Biosci. Biotechnol. Biochem. 72:1836-1846(2008) [PubMed: 18603769] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
[3]	"Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake." Gotthardt D., Blancheteau V., Bosserhoff A., Ruppert T., Delorenzi M., Soldati T. Mol. Cell. Proteomics 5:2228-2243(2006) [PubMed: 16926386] [Abstract] Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB213514 mRNA. Translation: BAD98567.1. AAFI02000125 Genomic DNA. Translation: EAS66835.1.
RefSeq	XP_001134518.1.
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	M16.003. M16.980.
Genome annotation databases
GeneID	4238181.
KEGG	ddi:DDB_0231799.
Organism-specific databases
dictyBase	DDB0231799. mppB.
Family and domain databases
InterPro	IPR011237. Pept_M16_core. IPR011765. Pept_M16_N. IPR001431. Pept_M16_Zn_BS. IPR007863. Peptidase_M16_C. [Graphical view]
Gene3D	G3DSA:3.30.830.10. Pept_M16_core. 2 hits.
Pfam	PF00675. Peptidase_M16. 1 hit. PF05193. Peptidase_M16_C. 1 hit. [Graphical view]
PROSITE	PS00143. INSULINASE. 1 hit. [Graphical view]

Entry information

Entry name

Q4W6B5_DICDI

Accession

Primary (citable) accession number: Q4W6B5
Secondary accession number(s): Q1ZXD0

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2005
Last sequence update:	July 5, 2005
Last modified:	September 23, 2008
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)